Forschungsthemen

  • Mediatoren des Energiestoffwechsels bei Adipositas und im Alter
  • Rolle von Makronährstoffen und Ballaststoffen im Energiestoffwechsel
  • Entwicklung des metabolischen Syndroms
  • Rolle von Fettgewebe und Muskulatur im Energiestoffwechsel
  • Mitochondrien und Mitokine

Ausgewählte Publikationen

Johann, K., Kleinert, M., Klaus, S.: The Role of GDF15 as a Myomitokine. Cells 10(11):2990 (2021). [Open Access]

Igual Gil, C., Coull, B. M., Jonas, W., Lippert, R., Ost, M., Klaus, S.: Mitochondrial stress-induced GDF15-GFRAL axis promotes anxiety-like behavior and CRH-dependent anorexia. bioRxiv preprint (2021). [Open Access]

Weindl, I., Ost, M., Wiedmer, P., Schreiner, M., Neugart, S., Klopsch, R., Kühnhold, H., Kloas, W., Henkel, I. M., Schlüter, O., Bußler, S., Bellingrath-Kimura, S. D., Ma, H., Grune, T., Rolinski, S., Klaus, S.: Sustainable food protein supply reconciling human and ecosystem health: A Leibniz Position. Global Food Security 25: 100367 (2020).

Ost, M., Igual Gil, C., Coleman, V., Keipert, S., Efstathiou, S., Vidic, V., Weyers, M., Klaus, S.: Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep. 21(3): e48804 (2020). [Open Access]

Bishop, C. A., Schulze, M. B., Klaus, S., Weitkunat, K.: The branched-chain amino acids valine and leucine have differential effects on hepatic lipid metabolism. Faseb J. 34(7), 9727-9739 (2020). [Open Access]

Norman, K., Klaus, S.: Veganism, aging and longevity: new insight into old concepts. Curr. Opin. Clin. Nutr. Metab. Care 23(2), 145-150 (2020).

Klaus, S., Ost, M.: Mitochondrial uncoupling and longevity - A role for mitokines? Exp. Gerontol. 130: 110796 (2020).

Gil, C. I., Ost, M., Kasch, J., Schumann, S., Heider, S., Klaus, S.: Role of GDF15 in active lifestyle induced metabolic adaptations and acute exercise response in mice. Sci. Rep. 9: 20120 (2019). [Open Access]