Forschungsthemen

• Intestinale Mikrobiota
• Physiologie und Ökologie von Darmbakterien
• Bioaktive Pflanzeninhaltsstoffe
• Umsetzung von Nahrungsbestandteilen durch bakterielle Enzyme
• Wirts-Mikrobiota-Interaktionen

Ausgewählte Publikationen

Goris, T., Cuadrat, R. R. C., Braune, A.: Flavonoid-Modifying Capabilities of the Human Gut Microbiome—An In Silico Study. Nutrients 13(8):2688 (2021). [Open Access]

Burkhardt, W., Rausch, T., Klopfleisch, R., Blaut, M., Braune, A.: Impact of dietary sulfolipid-derived sulfoquinovose on gut microbiota composition and inflammatory status of colitis-prone interleukin-10-deficient mice. Int. J. Med. Microbiol. 311(3):151494 (2021). [Open Access]

Braune, A., Gütschow, M., Blaut, M.: An NADH-Dependent Reductase from Eubacterium ramulus Catalyzes the Stereospecific Heteroring Cleavage of Flavanones and Flavanonols. Appl. Environ. Microbiol. 85(19):e01233-19 (2019).

Braune, A., Blaut, M.: Catenibacillus scindens gen. nov., sp. nov., a C-deglycosylating human intestinal representative of the Lachnospiraceae. Int. J. Syst. Evol. Microbiol. 68, 3356-3361 (2018).

Braune, A., Blaut, M.: Evaluation of inter-individual differences in gut bacterial isoflavone bioactivation in humans by PCR-based targeting of genes involved in equol formation. J. Appl. Microbiol. 124, 220-231 (2018).

Braune, A., Engst, W., Blaut, M.: Identification and functional expression of genes encoding flavonoid O- and C-glycosidases in intestinal bacteria. Environ. Microbiol. 18, 2117-2129 (2016). [Open Access]

Braune, A., Engst, W., Elsinghorst, P. W., Furtmann, N., Bajorath, J., Gütschow, M., Blaut, M.: Chalcone isomerase from Eubacterium ramulus catalyzes the ring contraction of flavanonols. J. Bacteriol. 198, 2965-2974 (2016). [Open Access]

Braune, A. Blaut, M.: Bacterial species involved in the conversion of dietary flavonoids in the human gut. Gut Microbes 7, 216-234 (2016). [Open Access]

Schröder, C., Matthies, A., Engst, W., Blaut, M., Braune, A.: Identification and expression of genes involved in the conversion of daidzein and genistein by the equol-forming bacterium Slackia isoflavoniconvertens. Appl. Environ. Microbiol. 79, 3494-3502 (2013).

Matthies, A., Loh, G., Blaut, M., Braune, A.: Daidzein and genistein are converted to equol and 5-hydroxy-equol by human intestinal Slackia isoflavoniconvertens in gnotobiotic rats. J. Nutr. 142, 40-46 (2012).