Die Abteilung Neurowissenschaft der Entscheidung und Ernährung (DNN) ist in der DFG-geförderten Forschungsgruppe 2698 „Kognitive Theorie des Tourette Syndroms - ein neuer Ansatz“ vertreten. Die Forschungsgruppe wird von der Universität zu Lübeck koordiniert und seit 2018 von der DFG gefördert.

Das Gilles de la Tourette Syndrom (GTS) ist eine häufige facettenreiche neuropsychiatrische Spektrumsstörung, die klinisch durch das Vorkommen motorischer und vokaler Tics charakterisiert ist und zu den neurologischen Entwicklungsstörungen gezählt wird. Obwohl es eine Vielzahl von Studien zum Tourette Syndrom sowohl bei Kindern als auch Erwachsenen gibt, existiert bislang kein übergeordnetes Konzept oder Model zum GTS.

Prof. Park arbeitet seit ihrem Wechsel von der Universität zu Lübeck an das DIfE im Jahr 2019 weiterhin in der Forschungsgruppe mit. In ihrem Teilprojekt „Modulation klinischer Phänomene und des Event File Codings durch repetitive transkranielle Magnetstimulation“ widmet sie sich der Untersuchung von supplementär motorischen und prä-supplementär motorischen Arealen (SMA und prä-SMA), die maßgeblich bei der Auswahl und Vorbereitung intern generierter Handlungen, dem Wechsel zwischen verschiedenen Handlungen und dem Überwinden habitueller Handlungen beteiligt sind. Die Hypothese ist, dass Tics und Dranggefühle beim GTS 'state marker' einer Überaktivität der SMA darstellen, die mit Veränderungen in der Integration von Wahrnehmung und Handlung einhergehen. Die zugrundeliegenden neurophysiologischen Prozesse sowie deren Modulierbarkeit durch repetitive transkranielle Magnetstimulation der SMA bzw. prä-SMA werden in diesem Projekt mittels EEG untersucht.

Zahedi, A., Artigas, S. O., Swaboda, N., Wiers, C. E., Görgen, K., Park, S. Q.: Neural correlates of changing food choices while bypassing values. Neuroimage 274:120134 (2023). [Open Access]

Zahedi, A., Öznur Akalin, R., Lawrence, J. E., Baumann, A., Sommer, W.: The nature and persistence of the effects of posthypnotic suggestions on food preferences: The final report of an online study. Front. Psychol. 14:1123907 (2023). [Open Access]

Bellucci, G., Münte, T. F., Park, S. Q.: Influences of social uncertainty and serotonin on gambling decisions. Sci. Rep. 12(1):10220 (2022). [Open Access]

Losecaat Vermeer, A. B., Muth, A., Terenzi, D., Park, S. Q.: Curiosity for information predicts wellbeing mediated by loneliness during COVID-19 pandemic. Sci. Rep. 12(1):7771 (2022). [Open Access]

Muth, A.-K., Losecaat Vermeer, A., Terenzi, D., Park, S. Q.: The impact of diet and lifestyle on wellbeing in adults during COVID-19 lockdown. Front. Nutr. 9:993180 (2022). [Open Access]

Rebollo, I., Tallon-Baudry, C.: The sensory and motor components of the cortical hierarchy are coupled to the rhythm of the stomach during rest. J. Neurosci. 42(11), 2205-2220 (2022). [Open Access]

Terenzi, D., Madipakkam, A. R., Molter, F., Mohr, P. N. C., Losecaat Vermeer, A. B., Liu, L., Park, S. Q.: Neural correlates underlying social-cue induced value change. J. Neurosci. 42(32), 6276-6284 (2022). [Open Access]

Terenzi, D., Muth, A.-K., Losecaat Vermeer, A., Park, S. Q.: Psychotic-like experiences in the lonely predict conspiratorial beliefs and are associated with the diet during COVID-19. Front. Nutr. 9:1006043 (2022). [Open Access]

Zahedi, A., Öznur Akalin, R., Lawrence, J. E., Baumann, A., Sommer, W.: The Nature and Persistence of Posthypnotic Suggestions’’ Effects on Food Preferences: An Online Study. Front. Nutr. 9:859656 (2022). [Open Access]

Fröhlich, E., Madipakkam, A. R., Craffonara, B., Bolte, C., Muth, A.-K., Park, S. Q: A short humorous intervention protects against subsequent psychological stress and attenuates cortisol levels without affecting attention. Sci. Rep. 11(1):7284 (2021). [Open Access]

Fröhlich, E., Samaan, L., Matsuzaki, R., Park, S. Q.: Humor and Hunger Affect the Response Toward Food Cues. Front. Psychol. 12:680508 (2021). [Open Access]

Liu, L., Artigas, S., Ulrich, A., Tardu, J., Wilms, B., Koletzko, B., Schmid, S. M., Park, S. Q.: Eating to dare - Nutrition impacts human risk decision and related brain function. Neuroimage 233:117951 (2021). [Open Access]

Rebollo, I., Schmidt, M., Longren, L., Park, S.: Influence of visual food cues on autonomic activity and craving. Biol. Psychol. 165:108197 (2021). [Open Access]

Bellucci, G., Park, S. Q.: Honesty biases trustworthiness impressions. J. Exp. Psy. Gen. 149(8), 1567-1586 (2020).

Melkonyan, A., Liu, L., Brown, E. C., Meyer, W., Madipakkam, A. R., Ringelmann, L., Lange, F., Schmid, S. M., Münte, T. F., Park, S. Q.: Unchanged food approach-avoidance behaviour of healthy men after oxytocin administration. J. Neuroendocr. 32(12):e12923 (2020). [Open Access]

Bellucci, G., Molter, F., Park, S. Q.: Neural representations of honesty predict future trust behavior. Nature Commun. 10:5184 (2019). [Open Access]

Bellucci, G., Münte, T. F., Park, S. Q.: Resting-state dynamics as a neuromarker of dopamine administration in healthy female adults. J. Psychopharmacol. 33, 955-964 (2019).

Madipakkam, A. R., Bellucci, G., Rothkirch, M., Park, S. Q.: The influence of gaze direction on food preferences. Sci. Rep. 9(1):5604 (2019). [Open Access]

Oroz Artigas, S., Liu, L., Strang, S., Burrasch, C., Hermsteiner, A., Munte, T. F., Park, S. Q.: Enhancement in dopamine reduces generous behaviour in women. PLoS One 14(12), 9 (2019). [Open Access]

Beyer, M., Liebig, J., Sylvester, T., Braun, M., Heekeren, H. R., Froehlich, E., Jacobs, A. M., Ziegler, J. C.: Structural gray matter features and behavioral preliterate skills predict future literacy - A machine learning approach. Front. Neurosci. 16:920150 (2022). [Open Access]

Chamorro, R., Kannenberg, S., Wilms, B., Kleinerüschkamp, C., Meyhöfer, S., Park, S. Q., Lehnert, H., Oster, H., Meyhöfer, S. M.: Meal Timing and Macronutrient Composition Modulate Human Metabolism and Reward-Related Drive to Eat. Nutrients 14(3), 562 (2022). [Open Access]

Janet, R., Ligneul, R., Losecaat-Vermeer, A. B., Philippe, R., Bellucci, G., Derrington, E., Park, S. Q., Dreher, J. C.: Regulation of social hierarchy learning by serotonin transporter availability. Neuropsychopharmacology 47, 2205–2212 (2022). [Open Access]

Müller, S. J., Teckentrup, V., Rebollo, I., Hallschmid, M., Kroemer, N. B.: Vagus nerve stimulation increases stomach-brain coupling via a vagal afferent pathway. Brain Stimul. 15(5), 1279-1289 (2022). [Open Access]

Sellitto, M., Terenzi, D., Starita, F., Di Pellegrino, G., Battaglia, S.: The Cost of Imagined Actions in a Reward-Valuation Task. Brain Sci. 12(5):582 (2022). [Open Access]

Terenzi, D., Catalan, M., Polverino, P., Bertolotti, C., Manganotti, P., Rumiati, R. I., Aiello, M.: Effects of tDCS on reward responsiveness and valuation in Parkinson’s patients with impulse control disorders. J. Neurol. 269, 1557–1565 (2022). [Open Access]

Wang, Z. L., Potenza, M. N., Song, K. R., Fang, X. Y., Liu, L., Ma, S. S., Xia, C. C., Lan, J., Yao, Y. W., Zhang, J. T.: Neural classification of internet gaming disorder and prediction of treatment response using a cue-reactivity fMRI task in young men. J. Psychiatr. Res. 145, 309-316 (2022).

Liu, L., Potenza, M. N., Lacadie, C. M., Zhang, J. T., Yip, S. W., Xia, C. C., Lan, J., Yao, Y. W., Deng, L. Y., Park, S. Q., Fang, X. Y.: Altered intrinsic connectivity distribution in internet gaming disorder and its associations with psychotherapy treatment outcomes. Addict. Biol. 26(2):e12917 (2021).

Ma, S. S., Li, C. S. R., Zhang, S., Worhunsky, P. D., Zhou, N., Zhang, J. T., Liu, L., Yao, Y. W., Fang, X. Y.: Altered functional network activities for behavioral adjustments and Bayesian learning in young men with Internet gaming disorder. J. Behav. Addict. 10(1), 112–122 (2021). [Open Access]

Song, K. R., Potenza, M. N., Fang, X. Y., Gong, G. L., Yao, Y. W., Wang, Z. L., Liu, L., Ma, S. S., Xia, C. C., Lan, J., Deng, L. Y., Wu, L. L., Zhang, J. T.: Resting-state connectome-based support-vector-machine predictive modeling of internet gaming disorder. Addict. Biol. 26(4):e12969 (2021).

Veselic, S., Jocham, G., Gausterer, C., Wagner, B., Ernhoefer-Reßler, M., Lanzenberger, R., Eisenegger, C., Lamm, C., Losecaat Vermeer, A.: A causal role of estradiol in human reinforcement learning. Horm. Behav. 134:105022 (2021).

Bellucci, G., Munte, T. F., Park, S. Q.: Effects of a dopamine agonist on trusting behaviors in females. Psychopharm. (Berl) 237(6), 1671–1680 (2020).

Hofmann-Shen, C., Vogel, B. O., Kaffes, M., Rudolph, A., Brown, E. C., Tas, C., Brune, M., Neuhaus, A. H.: Mapping adaptation, deviance detection, and prediction error in auditory processing. NeuroImage 207:116432 (2020).

Kumschick, I. R., Thiel, F., Goschin, C., Froehlich, E.: Decision-Making in Teaching Processes and the Role of Mood: A Study with Preservice Teachers in Germany. Intern. J. Emot. Educ. 12(2), 56-72 (2020). [Open Access]

Sadler, J. R., Shearrer, G. E., Acosta, N. T., Papantoni, A., Cohen, J. R., Small, D. M., Park, S. Q., Gordon-Larsen, P., Burger, K. S.: Network organization during probabilistic learning via taste outcomes. Physiol. Behav. 223:112962 (2020).

Wiesenfeller, J., Flasbeck, V., Brown, E. C., Brüne, M.: Approach and Avoidance Behavior in Female Patients With Borderline Personality Disorder. Front. Behav. Neurosci. 14:588874 (2020). [Open Access]

Yao, Y. W., Liu, L., Worhunsky, P. D., Lichenstein, S., Ma, S. S., Zhu, L., Shi, X. H., Yang, S., Zhang, J. T. and Yip, S. W.: Is monetary reward processing altered in drug-naïve youth with a behavioral addiction? Findings from internet gaming disorder. NeuroImage: Clin. 26:102202 (2020). [Open Access]

Kleimaker, M., Kleimaker, A., Beste, C., Park, S. Q., Munchau, A. M.: Gilles de la Tourette Syndrome A Model Disorder of Increased Perception-Action Binding?. Zeitschrift Fur Neuropsychologie 30(4), 215-221 (2019).

Waclawek, T., Park, S. Q.: Potential mechanisms and modulators of food intake during pregnancy. Front. Nutr. 10:1032430 (2023). [Open Access]

Terenzi, D., Muth, A.-K., Park, S. Q.: Nutrition and Gut-Brain Pathways Impacting the Onset of Parkinson’’s Disease. Nutrients 14(14):2781 (2022). [Open Access]

Yao, Y. W., Zhang, J. T., Fang, X. Y., Liu, L., Potenza, M. N.: Reward-related Decision-making Deficits in Internet Gaming Disorder: A Systematic Review and Meta-analysis. Addiction 117(1), 19-32 (2022). [Open Access]

Muth, A.-K., Park, S. Q.: The impact of dietary macronutrient intake on cognitive function and the brain. Clin. Nutr. 40(6), 3999-4010 (2021).

Rebollo, I., Wolpert, N., Tallon-Baudry, C.: Brain-stomach coupling: anatomy, functions, and future avenues of research. Curr. Opin. Biomed. Engin. 18:100270 (2021).

Terenzi, D., Liu, L., Bellucci, G., Park, S. Q.: Determinants and modulators of human social decisions. Neurosci. Biobehav. Rev. 128, 383-393 (2021). [Open Access]

Brown, E. C., Park, S. Q.: Obesity and addiction. Nat. Hum. Behav. 4, 10-11 (2020).