Ouni, M., Eichelmann, F., Jähnert, M., Krause, C., Saussenthaler, S., Ott, C., Gottmann, P., Speckmann, T., Huypens, P., Wolter, S., Mann, O., De Angelis, M. H., Beckers, J., Kirchner, H., Schulze, M. B., Schürmann, A.: Differences in DNA methylation of HAMP in blood cells predicts the development of type 2 diabetes. Mol. Metab. 75:101774 (2023). [Open Access]

Aga, H., Soultoukis, G., Stadion, M., Garcia-Carrizo, F., Jähnert, M., Gottmann, P., Vogel, H., Schulz, T. J., Schürmann, A.: Distinct Adipogenic and Fibrogenic Differentiation Capacities of Mesenchymal Stromal Cells from Pancreas and White Adipose Tissue. Int. J. Mol. Sci. 23(4):2108 (2022). [Open Access]

Bechmann, N., Calsina, B., Richter, S., Pietzsch, J.: Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma. J. Invest. Dermatol. 142(8), 2217-2227 (2022).

Gil, C. I., Coull, B. M., Jonas, W., Lippert, R., Ost, M., Klaus, S.: Mitochondrial stress-induced GDF15-GFRAL axis promotes anxiety-like behavior and CRH-dependent anorexia. Life Sci. Alliance 5(11):e202201495 (2022). [Open Access]

Gottmann, P., Speckmann, T., Stadion, M., Zuljan, E., Aga, H., Sterr, M., Büttner, M., Santos, P. M., Jähnert, M., Bornstein, S. R., Theis, F. J., Lickert, H., Schürmann, A.: Heterogeneous Development of β-Cell Populations In Diabetes-Resistant and -Susceptible Mice. Diabetes 71(9), 1962–1978 (2022).

Hauffe, R., Rath, M., Agyapong, W., Jonas, W., Vogel, H., Schulz, T. J., Schwarz, M., Kipp, A. P., Blüher, M., Kleinridders, A.: Obesity Hinders the Protective Effect of Selenite Supplementation on Insulin Signaling. Antioxidants 11(5):862 (2022). [Open Access]

Helm, J., Drukewitz, S., Poser, I., Richter, S., Friedemann, M., William, D., Mohr, H., Nölting, S., Robledo, M., Bornstein, S. R., Eisenhofer, G., Bechmann, N.: Treatment of Pheochromocytoma Cells with Recurrent Cycles of Hypoxia: A New Pseudohypoxic In Vitro Model. Cells 11(3):560 (2022). [Open Access]

Jonas, W., Kluth, O., Helms, A., Voß, S., Jähnert, M., Gottmann, P., Speckmann, T., Knebel, B., Chadt, A., Al-Hasani, H., Schürmann, A., Vogel, H.: Identification of Novel Genes Involved in Hyperglycemia in Mice. Int. J. Mol. Sci. 23(6):3205 (2022). [Open Access]

Jonas, W., Schwerbel, K., Zellner, L., Jähnert, M., Gottmann, P., Schürmann, A.: Alterations of Lipid Profile in Livers with Impaired Lipophagy. Int. J. Mol. Sci. 23(19):11863 (2022). [Open Access]

Bechmann, N., Watts, D., Steenblock, C., Wallace, P. W., Schürmann, A., Bornstein, S. R., Wielockx, B., Eisenhofer, G., Peitzsch, M.: Adrenal Hormone Interactions and Metabolism: A Single Sample Multi-Omics Approach. Horm. Metab. Res. 53(5), 326-334 (2021). [Open Access]

Hauffe, R., Rath, M., Schell, M., Ritter, K., Kappert, K., Deubel, S., Ott, C., Jähnert, M., Jonas, W., Schürmann, A., Kleinridders, A.: HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue. Mol. Metab. 53:101276 (2021). [Open Access]

Ouni, M., Gottmann, P., Westholm, E., Schwerbel, K., Jähnert, M., Stadion, M., Rittig, K., Vogel, H., Schürmann, A.: MiR-205 is upregulated in islets of diabetes-susceptible mice and targets the diabetes gene Tcf7l2. Acta Physiol. 232(4):e13693 (2021). [Open Access]

Stadion, M., Schürmann, A.: Intermittierendes Fasten. Psychotherapeut 66, 23-27 (2021). [Open Access]

Tuvia, N., Pivovarova-Ramich, O., Murahovschi, V., Lück, S., Grudziecki, A., Ost, A. C., Kruse, M., Nikiforova, V. J., Osterhoff, M., Gottmann, P., Gögebakan, Ö., Sticht, C., Gretz, N., Schupp, M., Schürmann, A., Rudovich, N., Pfeiffer, A. F. H., Kramer, A.: Insulin directly regulates the circadian clock in adipose tissue. Diabetes 70(9), 1985-1999 (2021).

Wardelmann, K., Rath, M., Castro, J. P., Blümel, S., Schell, M., Hauffe, R., Schumacher, F., Flore, T., Ritter, K., Wernitz, A., Hosoi, T., Ozawa, K., Kleuser, B., Weiß, J., Schürmann, A., Kleinridders, A.: Central Acting Hsp10 Regulates Mitochondrial Function, Fatty Acid Metabolism, and Insulin Sensitivity in the Hypothalamus. Antioxidants 10(5):711 (2021). [Open Access]

Wilhelmi, I., Grunwald, S., Gimber, N., Popp, O., Dittmar, G., Arumughan, A., Wanker, E. E., Laeger, T., Schmoranzer, J., Daumke, O., Schürmann, A.: The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells. Mol. Metab. 45:101151 (2021). [Open Access]

Wilhelmi, I., Neumann, A., Jähnert, M., Ouni, M., Schürmann, A.: Enriched Alternative Splicing in Islets of Diabetes-Susceptible Mice. Intern. J. Mol. Sci. 22(16):8597 (2021). [Open Access]

Aga, H., Hallahan, N., Gottmann, P., Jaehnert, M., Osburg, S., Schulze, G., Kamitz, A., Arends, D., Brockmann, G., Schallschmidt, T., Lebek, S., Chadt, A., Al-Hasani, H., Joost, H.-G., Schürmann, A., Vogel, H.: Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning. Front. Genet. 11:567191 (2020). [Open Access]

Bechmann, N., Moskopp, M. L., Ullrich, M., Calsina, B., Wallace, P. W., Richter, S., Friedemann, M., Langton, K., Fliedner, S. M. J., Timmers, H., Nölting, S., Beuschlein, F., Fassnacht, M., Prejbisz, A., Pacak, K., Ghayee, H. K., Bornstein, S. R., Dieterich, P., Pietzsch, J., Wielockx, B., Robledo, M., Qin, N., Eisenhofer, G.: HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas. Endocr. Relat. Cancer 27(11), 625-640 (2020).

Drechsel, A., Helm, J., Ehrlich, H., Pantovic, S., Bornstein, S. R., Bechmann, N.: Anti-Tumor Activity vs. Normal Cell Toxicity: Therapeutic Potential of the Bromotyrosines Aerothionin and Homoaerothionin In Vitro. Mar. Drugs 18(5):236 (2020). [Open Access]

Gottmann, P., Ouni, M., Zellner, L., Jähnert, M., Rittig, K., Walther, D., Schürmann, A.: Polymorphisms in miRNA binding sites involved in metabolic diseases in mice and humans. Sci. Rep. 10(1):7202 (2020). [Open Access]

Kehm, R., Jähnert, M., Deubel, S., Flore, T., König, J., Jung, T., Stadion, M., Jonas, W., Schürmann, A., Grune, T., Höhn, A.: Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: role of Thioredoxin-interacting protein (TXNIP). Red. Bio. 37:101748 (2020). [Open Access]

Ouni, M., Saussenthaler, S., Eichelmann, F., Jähnert, M., Stadion, M., Wittenbecher, C., Rönn, T., Zellner, L., Gottmann, P., Ling, C., Schulze, M. B., Schürmann, A.: Epigenetic Changes in Islets of Langerhans Preceding the Onset of Diabetes. Diabetes 69(11), 2503-2517 (2020). [Open Access]

Ouni, M., Schürmann, A.: Epigenetic contribution to obesity. Mamm. Gen. 31, 134–145 (2020). [Open Access]

Schwerbel, K., Kamitz, A., Krahmer, N., Hallahan, N., Jähnert, M., Gottmann, P., Lebek, S., Schallschmidt, T., Arends, D., Schumacher, F., Kleuser, B., Haltenhof, T., Heyd, F., Gancheva, S., Broman, K. W., Roden, M., Joost, H.-G., Chadt, A., Al-Hasani, H., Vogel, H., Jonas, W., Schürmann, A.: Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation. J. Hepatol. 73(4), 771-782 (2020). [Open Access]

Castaño-Martinez, T., Schumacher, F., Schumacher, S., Kochlik, B., Weber, D., Grune, T., Biemann, R., McCann, A., Abraham, K., Weikert, C., Kleuser, B., Schürmann, A., Laeger, T.: Methionine restriction prevents onset of type 2 diabetes in NZO mice. FASEB J. 33, 7092–7102 (2019). [Open Access]

Gancheva, S., Ouni, M., Jelenik, T., Koliaki, C., Szendroedi, J., Toledo, F. G. S., Markgraf, D. F., Pesta, D. H., Mastrototaro, L., De Filippo, E., Herder, C., Jähnert, M., Weiss, J., Strassburger, K., Schlensak, M., Schürmann, A., Roden, M.: Dynamic changes of muscle insulin sensitivity after metabolic surgery. Nat. Commun. 10(1):4179 (2019). [Open Access]

Gohlke, S., Zagoriy, V., Cuadros Inostroza, A., Méret, M., Mancini, C., Japtok, L., Schumacher, F., Kuhlow, D., Graja, A., Stephanowitz, H., Jähnert, M., Krause, E., Wernitz, A., Petzke, K.-J., Schürmann, A., Kleuser, B., Schulz, T. J.: Identification of functional lipid metabolism biomarkers of brown adipose tissue aging. Mol. Metab. 24, 1-17 (2019). [Open Access]

Hill, C. M., Laeger, T., Dehner, M., Albarado, D. C., Clarke, B., Wanders, D., Burke, S. J., Collier, J. J., Qualls-Creekmore, E., Solon-Biet, S. M., Simpson, S. J., Berthoud, H.-R., Münzberg, H., Morrison, C. D.: FGF21 signals protein status to the brain and adaptively regulates food choice and metabolism. Cell Rep. 27, 2934-2947.e3 (2019). [Open Access]

Kluth, O., Stadion, M., Gottmann, P., Aga, H., Jähnert, M., Scherneck, S., Vogel, H., Krus, U., Seelig, A., Ling, C., Gerdes, J., Schürmann, A.: Decreased Expression of cilia genes in pancreatic islets as a risk factor for type 2 diabetes in mice and humans. Cell Rep. 26, 3027-3036.e3 (2019). [Open Access]

Quiclet, C., Dittberner, N., Gässler, A., Stadion, M., Gerst, F., Helms, A., Baumeier, C., Schulz, T. J., Schürmann, A.: Pancreatic adipocytes mediate hypersecretion of insulin in diabetes-susceptible mice. Metabolism. 97, 9-17 (2019).

Saussenthaler, S., Ouni, M., Baumeier, C., Schwerbel, K., Gottmann, P., Christmann, S., Laeger, T., Schürmann, A.: Epigenetic regulation of hepatic Dpp4 expression in response to dietary protein. J. Nutr. Biochem. 63, 109-116 (2019).

Wittenbecher, C., Ouni, M., Kuxhaus, O., Jähnert, M., Gottmann, P., Teichmann, A., Meidtner, K., Kriebel, J., Grallert, H., Pischon, T., Boeing, H., Schulze, M. B., Schürmann, A.: Insulin-like growth factor binding protein 2 (IGFBP-2) and the risk of developing type 2 diabetes. Diabetes 68, 188-197 (2019).

Gottmann, P., Ouni, M., Sausenthaler, S., Roos, J., Stirm, L., Jähnert, M., Kamitz, A., Hallahan, N., Jonas, W., Fritsche, A., Häring, H.-U., Staiger, H., Blüher, M., Fischer-Posovszky, P., Vogel, H., Schürmann, A.: A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes. Mol. Metab. 11, 145-159 (2018). [Open Access]

Graja, A., Garcia-Carrizo, F., Jank, A.-M., Gohlke, S., Ambrosi, T. H., Jonas, W., Ussar, S., Kern, M., Schürmann, A., Aleksandrova, K., Blüher, M., Schulz, T. J.: Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism. Aging Cell 17: e12810 (2018). [Open Access]

Hörbelt, T., Tacke, C., Markova, M., Herzfeld de Wiza, D., Van de Velde, F., Bekaert, M., Van Nieuwenhove, Y., Hornemann, S., Rödiger, M., Seebeck, N., Friedl, E., Jonas, W., Thoresen, G. H., Kuss, O., Rosenthal, A., Lange, V., Pfeiffer, A. F. H., Schürmann, A., Lapauw, B., Rudovich, N., Pivovarova, O., Ouwens, D. M.: The novel adipokine WISP1 associates with insulin resistance and impairs insulin action in human myotubes and mouse hepatocytes. Diabetologia 61, 2054-2065 (2018).

Kasch, J., Kanzleiter, I., Saussenthaler, S., Schürmann, A., Keijer, J., van Schothorst, E., Klaus, S., Schumann, S.: Insulin sensitivity linked skeletal muscle Nr4a1 DNA methylation is programmed by the maternal diet and modulated by voluntary exercise in mice. J. Nutr. Biochem. 57, 86-92 (2018).

Laeger, T., Castaño-Martinez, T., Werno, M. W., Japtok, L., Baumeier, C., Jonas, W., Kleuser, B., Schürmann, A.: Dietary carbohydrates impair the protective effect of protein restriction against diabetes in NZO mice used as a model of type 2 diabetes. Diabetologia 61, 1459-1469 (2018). [Open Access]

Rödiger, M., Werno, M. W., Wilhelmi, I., Baumeier, C., Hesse, D., Wettschureck, N., Offermanns, S., Song, K., Krauß, M., Schürmann, A.: Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes. Mol. Metab. 8, 167-179 (2018). [Open Access]

Stadion, M., Schwerbel, K., Graja, A., Baumeier, C., Rödiger, M., Jonas, W., Wolfrum, C., Staiger, H., Fritsche, A., Häring, H.-U., Klöting, N., Blüher, M., Fischer-Posovszky, P., Schulz, T. J., Joost, H.-G., Vogel, H., Schürmann, A.: Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans. Diabetologia 61, 1167-1179 (2018). [Open Access]

Vogel, H., Kamitz, A., Hallahan, N., Lebek, S., Schallschmidt, T., Jonas, W., Jähnert, M., Gottmann, P., Zellner, L., Kanzleiter, T., Damen, M., Altenhofen, D., Burkhardt, R., Renner, S., Dahlhoff, M., Wolf, E., Müller, T. D., Blüher, M., Joost, H.-G., Chadt, A., Al-Hasani, H., Schürmann, A.: A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and type 2 diabetes. Hum. Mol. Genet. 27, 3099-3113 (2018). [Open Access]

Werno, M. W., Wilhelmi, I., Kuropka, B., Ebert, F., Freund, C., Schürmann, A.: The GTPase ARFRP1 affects lipid droplet protein composition and triglyceride release from intracellular storage of intestinal Caco-2 cells. Biochem. Biophys. Res. Commun. 506, 259-265 (2018). [Open Access]

Ambrosi, T. H., Scialdone, A., Graja, A., Gohlke, S., Jank, A.-M., Bocian, C., Woelk, L., Fan, H., Logan, D. W., Schürmann, A., Saraiva, L. R., Schulz, T. J.: Adipocyte accumulation in the bone marrow during obesity and aging impairs stem cell-based hematopoietic and bone regeneration. Cell Stem Cell 20, 771-784 (2017). [Open Access]

Baumeier, C., Saussenthaler, S., Kammel, A., Jähnert, M., Schlüter, L., Hesse, D., Canouil, M., Lobbens, S., Caiazzo, R., Raverdy, V., Pattou, F., Nilsson, E., Pihlajamäki, J., Ling, C., Froguel, P., Schürmann, A., Schwenk, R. W.: Hepatic DPP4 DNA-methylation associates with fatty liver. Diabetes 6, 25-35 (2017). [Open Access]

Baumeier, C., Schlüter, L., Saussenthaler, S., Laeger, T., Rödiger, M., Alaze, S. A., Fritsche, L., Häring, H.-U., Stefan, N., Fritsche, A., Schwenk, R. W., Schürmann, A.: Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease. Mol. Metab. 6, 1254–1263 (2017). [Open Access]

Laeger, T., Baumeier, C., Wilhelmi, I., Würfel, J., Kamitz, A., Schürmann, A.: FGF21 improves glucose homeostasis in an obese diabetes-prone mouse model independent of body fat changes. Diabetologia 60, 2274–2284 (2017). [Open Access]

Speckmann, B., Schulz, S., Hiller, F., Hesse, D., Schumacher, F., Kleuser, B., Geisel, J., Obeid, R., Grune, T., Kipp, A. P.: Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice. J. Nutr. Biochem. 48, 112-119 (2017). [Open Access]

Vogel, H., Jähnert, M., Stadion, M., Matzke, D., Scherneck, S., Schürmann, A.: A vast genomic deletion in the C56BL/6 genome affects different genes within the Ifi200 cluster on chromosome 1 and mediates obesity and insulin resistance. BMC Genomics 18:172 (2017). [Open Access]

Vogel, H., Kraemer, M., Rabasa, C., Askevik, K., Adan, R. A. H., Dickson, S. L.: Genetic predisposition to obesity affects behavioural traits including food reward and anxiety-like behaviour in rats. Behav. Brain Res. 328, 95-104 (2017). [Open Access]

Kammel, A., Saussenthaler, S., Jähnert, M., Jonas, W., Stirm, L., Hoeflich, A., Staiger, H., Fritsche, A., Häring, H. U., Joost, H.-G., Schürmann, A., Schwenk, R. W.: Early hypermethylation of hepatic Igfbp2 results in its reduced expression preceding fatty liver in mice. Hum. Mol. Genet. 25, 2588-2599 (2016). [Open Access]

Laeger, T., Albarado, D. C., Burke, S. J., Trosclair, L., Hedgepeth, J. W., Berthoud, H. R., Gettys, T. W., Collier, J. J., Münzberg, H., Morrison, C. D.: Metabolic responses to dietary protein restriction require an increase in FGF21 that is delayed by the absence of GCN2. Cell Rep. 16, 707-716 (2016). [Open Access]

Vogel, H., Wolf, S., Rabasa, C., Rodriguez-Pacheco, F., Babaei, C. S., Stöber, F., Goldschmidt, J., DiMarchi, R. D., Finan, B., Tschöp, M. H., Dickson, S. L., Schürmann, A., Skibicka, K. P.: GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight. Neuropharmacology 110, 396-406 (2016). [Open Access]

Wilhelmi, I., Kanski, R., Neumann, A., Herdt, O., Hoff, F., Jacob, R., Preußner, M., Heyd, F.: Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat. Commun. 7:12347 (2016). [Open Access]

Baumeier, C., Kaiser, D., Heeren, J., Scheja, L., John, C., Weise, C., Eravci, M., Lagerpusch, M., Schulze, G., Joost, H.-G., Schwenk, R. W., Schürmann, A.: Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice. Biochim. Biophys. Acta/Mol. Cell Biol. Lipids 1851, 566-576 (2015). [Open Access]

Chung, B., Stadion, M., Schulz, N., Jain, D., Scherneck, S., Joost, H.-G., Schürmann, A.: The diabetes gene Zfp69 modulates hepatic insulin sensitivity in mice. Diabetologia 58, 2403-2413 (2015). [Open Access]

Jonas, W., Lietzow, J., Wohlgemuth, F., Hoefig, C. S., Wiedmer, P., Schweizer, U., Köhrle, J., Schürmann, A.: 3,5-Diiodo-L-thyronine (3,5-T2) exerts thyromimetic effects on hypothalamus-pituitary-thyroid axis, body composition, and energy metabolism in male diet-induced obese mice. Endocrinology 156, 389-399 (2015). [Open Access]

Kanzleiter, T., Jähnert, M., Schulze, G., Selbig, J., Hallahan, N., Schwenk, R. W., Schürmann, A.: Exercise training alters DNA methylation patterns in genes related to muscle growth and differentiation in mice. Am. J. Physiol./Endocrinol. Metab. 308, E912-E920 (2015). [Open Access]

Kluth, O., Matzke, D., Kamitz, A., Jähnert, M., Vogel, H., Scherneck, S., Schulze, M., Staiger, H., Machicao, F., Häring, H. U., Joost, H.-G., Schürmann, A.: Identification of four mouse diabetes candidate genes altering β-cell proliferation. PLoS Genet. 11(9):e1005506 (2015). [Open Access]

Lubura ,M., Hesse, D., Kraemer, M., Hallahan, N., Schupp, M., von Loeffelholz, C., Kriebel, J., Rudovich, N. N., Pfeiffer, A., John, C., Scheja, L., Heeren, J., Koliaki, C., Roden, M., Schürmann, A.: Diabetes prevalence in NZO females depends on estrogen action on liver fat content. Am. J. Physiol./Endocrinol. Metab. 309, E968-E980 (2015). [Open Access]

Schwenk, R. W., Baumeier, C., Finan, B., Kluth, O., Brauer, C., Joost, H.-G., DiMarchi, R. D., Tschöp, M. H., Schürmann, A.: GLP-1-oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice. Diabetologia 58, 604-614 (2015). [Open Access]

Voigt, A., Katterle, Y., Kahle, M., Kluge, R., Schürmann, A., Joost, H. G., Klaus, S.: Skeletal muscle mitochondrial uncoupling prevents diabetes but not obesity in NZO mice, a model for polygenic diabesity. Genes Nutr. 10(6):57 (2015). [Open Access]

Wiedmer, P., Schwarz, F., Große, B., Schindler, N., Tuchscherer, A., Russo, V. C., Tschöp, M. H., Hoeflich, A.: Gender-specific effects on food intake but no inhibition of age-related fat accretion in transgenic mice overexpressing human IGFBP-2 lacking the Cardin-Weintraub sequence motif. J. Cell Commun. Signal. 9, 143-150 (2015). [Open Access]

Altenhofen, D., Khuong, J. M.-A., Kuhn, T., Lebek, S., Görigk, S., Kaiser, K., Binsch, C., Griess, K., Knebel, B., Belgardt, B.-F., Cames, S., Eickelschulte, S., Stermann, T., Rasche, A., Herwig, R., Weiss, J., Vogel, H., Schürmann, A., Chadt, A., Al-Hasani, H.: E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice. Int. J. Mol. Sci. 24(1):845 (2023). [Open Access]

van Egmond, L. T., Meth, E. M. S., Engström, J., Ilemosoglou, M., Keller, J. A., Vogel, H., Benedict, C.: Effects of acute sleep loss on leptin, ghrelin, and adiponectin in adults with healthy weight and obesity: A laboratory study. Obesity (Silver Spring) 31(3), 635-641 (2023). [Open Access]

Wagner, R., Heni, M., Kantartzis, K., Sandforth, A., Machann, J., Schick, F., Peter, A., Fritsche, L., Szendrödi, J., Pfeiffer, A. F., Schürmann, A., Blüher, M., Hauner, H., Seissler, J., Bornstein, S., Roden, M., Stefan, N., Birkenfeld, A. L., White, M. F., Häring, H. U., Fritsche, A.: Lower Hepatic Fat is Associated with Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention. Diabetes 72(3), 362–366 (2023). [Open Access]

Zhang, Z., Venditti, R., Ran, L., Liu, Z., Vivot, K., Schürmann, A., Bonifacino, J. S., De Matteis, M. A., Ricci, R.: Distinct changes in endosomal composition promote NLRP3 inflammasome activation. Nat. Immunol. 24, 30-41 (2023). [Open Access]

Delpero, M., Arends, D., Sprechert, M., Krause, F., Kluth, O., Schürmann, A., Brockmann, G. A., Hesse, D.: Identification of four novel QTL linked to the metabolic syndrome in the Berlin Fat Mouse. Int. J. Obesity 46, 307-315 (2022). [Open Access]

Fritsche, L., Heni, M., Eckstein, S. S., Hummel, J., Schürmann, A., Häring, H. U., Preißl, H., Birkenfeld, A. L., Peter, A., Fritsche, A., Wagner, R.: Incretin hypersecretion in gestational diabetes mellitus. J. Clin. Endocrinol. Metab. 107(6), e2425-e2430 (2022).

Fritsche, L., Hummel, J., Wagner, R., Löffler, D., Hartkopf, J., Machann, J., Hilberath, J., Kantartzis, K., Jakubowski, P., Pauluschke-Fröhlich, J., Brucker, S., Hörber, S., Häring, H. U., Roden, M., Schürmann, A., Solimena, M., de Angelis, M. H., Peter, A., Birkenfeld, A. L., Preissl, H., Fritsche, A., Heni, M.: The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: rationale, methodology and design. BMJ Open 12(2):e058268 (2022). [Open Access]

Gancheva, S., Ouni, M., Jelenik, T., Koliaki, C., Szendroedi, J., Toledo, F. G. S., Markgraf, D. F., Pesta, D. H., Mastrototaro, L., De Filippo, E., Herder, C., Jähnert, M., Weiss, J., Strassburger, K., Schlensak, M., Schürmann, A., Roden, M.: Author Correction: Dynamic changes of muscle insulin sensitivity after metabolic surgery. Nat. Commun. 13(1):3353 (2022). [Open Access]

Görigk, S., Ouwens, D. M., Kuhn, T., Altenhofen, D., Binsch, C., Damen, M., Khuong, J. M., Kaiser, K., Knebel, B., Vogel, H., Schürmann, A., Chadt, A., Al-Hasani, H.: Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1867(6):159153 (2022).

Hengstler, J. G., Baum, M., Cartus, A. T., Diel, P., Eisenbrand, G., Engel, K. H., Engeli, B., Epe, B., Grune, T., Guth, S., Haller, D., Heinz, V., Hellwig, M., Henle, T., Humpf, H. U., Jager, H., Joost, H. G., Kulling, S. E., Lachenmeier, D. W., Lampen, A., Leist, M., Mally, A., Marko, D., Nothlings, U., Rohrdanz, E., Roth, A., Spranger, J., Stadler, R., Steinberg, P., Vieths, S., Watjen, W.: Opinion on acetaldehyde as a flavouring substance: considerations for risk assessment. J. Consum. Prot. Food Saf. 17, 285-293 (2022). [Open Access]

Kuhn, T., Kaiser, K., Lebek, S., Altenhofen, D., Knebel, B., Herwig, R., Rasche, A., Pelligra, A., Görigk, S., Khuong, J. M., Vogel, H., Schürmann, A., Blüher, M., Chadt, A., Al-Hasani, H.: Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene. Hum. Mol. Genet. 31(23), 4019-4033 (2022). [Open Access]

Mateus Brandão, L. E., Espes, D., Westholm, J. O., Martikainen, T., Westerlund, N., Lampola, L., Popa, A., Vogel, H., Schürmann, A., Dickson, S. L., Benedict, C., Cedernaes, J.: Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans: A randomised crossover trial. J. Sleep Res. 31(2):e13472 (2022). [Open Access]

Qin, N., Paisana, E., Langini, M., Picard, D., Malzkorn, B., Custódia, C., Cascão, R., Meyer, F. D., Blümel, L., Göbbels, S., Taban, K., Bartl, J., Bechmann, N., Conrad, C., Gravemeyer, J., Becker, J. C., Stefanski, A., Puget, S., Barata, J. T., Stühler, K., Fischer, U., Felsberg, J., Ayrault, O., Reifenberger, G., Borkhardt, A., Eisenhofer, G., Faria, C. C., Remke, M.: Intratumoral heterogeneity of MYC drives medulloblastoma metastasis and angiogenesis. Neuro Oncol. 24(9), 1509–1523 (2022).

Shih, A. Z. L., Chen, Y. C., Speckmann, T., Søndergaard, E., Schürmann, A., Verchere, C. B., Willnow, T. E.: SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition. Mol. Metab. 65:101585 (2022). [Open Access]

Bechmann, N., Berger, I., Bornstein, S. R., Steenblock, C.: Adrenal medulla development and medullary-cortical interactions. Mol. Cell. Endocrinol. 528:111258 (2021).

Bühler, L., Maida, A., Vogl, E. S., Georgiadi, A., Takacs, A., Kluth, O., Schürmann, A., Feuchtinger, A., von Toerne, C., Tsokanos, F. F., Klepac, K., Wolff, G., Sakurai, M., Ekim Üstünel, B., Nawroth, P., Herzig, S.: Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control. Life Sci. Alli. 4(4):e202000898 (2021). [Open Access]

Chen, J., Spracklen, C. N., Marenne, G., Varshney, A., [...], Schürmann, A., [...], Parker, S. C. J., Mohlke, K. L., Langenberg, C., Wheeler, E., Morris, A. P., Barroso, I.: The trans-ancestral genomic architecture of glycemic traits. Nature Genet. 53(6), 840-860 (2021). [Open Access]

Eisenhofer, G., Deutschbein, T., Constantinescu, G., Langton, K., Pamporaki, C., Calsina, B., Monteagudo, M., Peitzsch, M., Fliedner, S., Timmers, H., Bechmann, N., Fankhauser, M., Nölting, S., Beuschlein, F., Stell, A., Fassnacht, M., Prejbisz, A., Lenders, J. W. M., Robledo, M.: Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma. Clin. Chem. Lab. Med. 59(2), 353-363 (2021).

Friedemann, M., Horn, F., Gutewort, K., Tautz, L., Jandeck, C., Bechmann, N., Sukocheva, O., Wirth, M. P., Fuessel, S., Menschikowski, M.: Increased Sensitivity of Detection of RASSF1A and GSTP1 DNA Fragments in Serum of Prostate Cancer Patients: Optimisation of Diagnostics Using OBBPA-ddPCR. Cancers 13(17), 4459 (2021). [Open Access]

Fritsche, A., Wagner, R., Heni, M., Kantartzis, K., Machann, J., Schick, F., Lehmann, R., Peter, A., Dannecker, C., Fritsche, L., Valenta, V., Schick, R., Nawroth, P. P., Kopf, S., Pfeiffer, A. F., Kabisch, S., Dambeck, U., Stumvoll, M., Blüher, M., Birkenfeld, A. L., Schwarz, P., Hauner, H., Clavel, J., Seißler, J., Lechner, A., Müssig, K., Weber, K., Laxy, M., Bornstein, S., Schürmann, A., Roden, M., de Angelis, M. H., Stefan, N., Häring, H. U.: Different effects of lifestyle intervention in high- and low-risk prediabetes. Diabetes 70(12), 2785-2795 (2021).

Murakami, M., Sun, N., Greunke, C., Feuchtinger, A., Kircher, S., Deutschbein, T., Papathomas, T., Bechmann, N., Wallace, P. W., Peitzsch, M., Korpershoek, E., Friemel, J., Gimenez-Roqueplo, A. P., Robledo, M., Timmers, H., Canu, L., Weber, A., De Krijger, R. R., Fassnacht, M., Knosel, T., Kirchner, T., Reincke, M., Walch, A. K., Kroiss, M., Beuschlein, F.: Mass spectrometry imaging identifies metabolic patterns associated with malignant potential in pheochromocytoma and paraganglioma. Eur. J. Endocrinol. 185(1), 179-191 (2021).

Rehman, S. u., Schallschmidt, T., Rasche, A., Knebel, B., Stermann, T., Altenhofen, D., Herwig, R., Schürmann, A., Chadt, A., Al-Hasani, H.: Alternative exon splicing and differential expression in pancreatic islets reveals candidate genes and pathways implicated in early diabetes development. Mamm. Genome 32, 153–172 (2021). [Open Access]

Seifert, V., Richter, S., Bechmann, N., Bachmann, M., Ziegler, C. G., Pietzsch, J., Ullrich, M.: HIF2alpha-Associated Pseudohypoxia Promotes Radioresistance in Pheochromocytoma: Insights from 3D Models. Cancers (Basel) 13(3):385 (2021). [Open Access]

Steenblock, C., Richter, S., Berger, I., Barovic, M., Schmid, J., Schubert, U., Jarzebska, N., von Mässenhausen, A., Linkermann, A., Schürmann, A., Pablik, J., Dienemann, T., Evert, K., Rodionov, R. N., Semenova, N. Y., Zinserling, V. A., Gainetdinov, R. R., Baretton, G., Lindemann, D., Solimena, M., Ludwig, B., Bornstein, S. R.: Viral infiltration of pancreatic islets in patients with COVID-19. Nat. Commun. 12(1):3534 (2021). [Open Access]

Trujillo-Viera, J., El-Merahbi, R., Schmidt, V., Karwen, T., Loza-Valdes, A., Strohmeyer, A., Reuter, S., Noh, M., Wit, M., Hawro, I., Mocek, S., Fey, C., Mayer, A. E., Löffler, M. C., Wilhelmi, I., Metzger, M., Ishikawa, E., Yamasaki, S., Rau, M., Geier, A., Hankir, M., Seyfried, F., Klingenspor, M., Sumara, G.: Protein Kinase D2 drives chylomicron-mediated lipid transport in the intestine and promotes obesity. EMBO Mol. Med. 13(5):e13548 (2021). [Open Access]

Voisin, S., Jacques, M., Landen, S., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Gancheva, S., Ouni, M., Jähnert, M., Ashton, K. J., Coffey, V. G., Thompson, J. M., Doering, T. M., Gabory, A., Junien, C., Caiazzo, R., Verkindt, H., Raverdy, V., Pattou, F., Froguel, P., Craig, J. M., Blocquiaux, S., Thomis, M., Sharples, A. P., Schürmann, A., Roden, M., Horvath, S., Eynon, N.: Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle. J. Cachexia Sarcopenia Muscle 12(4), 1064-1078 (2021). [Open Access]

Watts, D., Stein, J., Meneses, A., Bechmann, N., Neuwirth, A., Kaden, D., Krüger, A., Sinha, A., Alexaki, V. I., Luis Gustavo, P.-R., Kircher, S., Martinez, A., Theodoropoulou, M., Eisenhofer, G., Peitzsch, M., El-Armouche, A., Chavakis, T., Wielockx, B.: HIF1α is a direct regulator of steroidogenesis in the adrenal gland. Cell. Mol. Life Sci. 78, 3577–3590 (2021). [Open Access]

Bodis, K., Jelenik, T., Lundbom, J., Markgraf, D. F., Strom, A., Zaharia, O. P., Karusheva, Y., Burkart, V., Mussig, K., Kupriyanova, Y., Ouni, M., Wolkersdorfer, M., Hwang, J. H., Ziegler, D., Schürmann, A., Roden, M., Szendroedi, J.: Expansion and impaired mitochondrial efficiency of deep subcutaneous adipose tissue in recent-onset type 2 diabetes. J. Clin. Endocrinol. Metab. 105(4), e1331-e1343 (2020). [Open Access]

Grupe, K., Pfeifer, M. A., Dannehl, F., Liebmann, M., Rustenbeck, I., Schürmann, A., Scherneck, S.: Metabolic changes during pregnancy in glucose‐intolerant NZO mice: A polygenic model with prediabetic metabolism. Phys. Rep. 8(9):e14417 (2020). [Open Access]

Guth, S., Roth, A., Engeli, B., Lachenmeier, D. W., Cartus, A. T., Hüser, S., Baum, M., Diel, P., Eisenbrand, G., Hengstler, J. G., Humpf, H. U., Joost, H. G., Lampen, A., Leist, M., Marko, D., Steinberg, P., Mally, A., Zarn, J.: Comparison of points of departure between subchronic and chronic toxicity studies on food additives, food contaminants and natural food constituents. Food Chem. Toxicol. 146:111784 (2020). [Open Access]

Jiang, J., Zhang, J., Pang, Y., Bechmann, N., Li, M., Monteagudo, M., Calsina, B., Gimenez-Roqueplo, A. P., Nölting, S., Beuschlein, F., Fassnacht, M., Deutschbein, T., Timmers, H., Åkerström, T., Crona, J., Quinkler, M., Fliedner, S. M. J., Liu, Y., Guo, J., Li, X., Guo, W., Hou, Y., Wang, C., Zhang, L., Xiao, Q., Liu, L., Gao, X., Burnichon, N., Robledo, M., Eisenhofer, G.: Sino-European differences in the genetic landscape and clinical presentation of pheochromocytoma and paraganglioma. J. Clin. Endocrinol. Metab. 105(10):dgaa502 (2020).

Machalowski, T., Czajka, M., Petrenko, I., Meissner, H., Schimpf, C., Rafaja, D., Zietek, J., Dziegiel, B., Adaszek, L., Voronkina, A., Kovalchuk, V., Jaroszewicz, J., Fursov, A., Rahimi-Nasrabadi, M., Stawski, D., Bechmann, N., Jesionowski, T., Ehrlich, H.: Functionalization of 3D Chitinous Skeletal Scaffolds of Sponge Origin Using Silver Nanoparticles and Their Antibacterial Properties. Mar. Drugs 18(6):304 (2020). [Open Access]

Matthaeus, C., Lahmann, I., Kunz, S., Jonas, W., Melo, A. A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Bluher, M., Olschowski, H., Kompa, J., Brugger, B., Muller, D. N., Haucke, V., Schürmann, A., Birchmeier, C., Daumke, O.: EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake. PNAS 117(13), 7471-7481 (2020). [Open Access]

McNulty, M. A., Goupil, B. A., Albarado, D. C., Castano-Martinez, T., Ambrosi, T. H., Puh, S., Schulz, T. J., Schürmann, A., Morrison, C. D., Laeger, T.: FGF21, not GCN2, influences bone morphology due to dietary protein restrictions. Bone Rep. 12:100241 (2020). [Open Access]

Otto, C., Friedrich, A., Vrhovac Madunić, I., Baumeier, C., Schwenk, R. W., Karaica, D., Germer, C. T., Schürmann, A., Sabolić, I., Koepsell, H.: Antidiabetic Effects of a Tripeptide That Decreases Abundance of Na(+)-d-glucose Cotransporter SGLT1 in the Brush-Border Membrane of the Small Intestine. ACS Omega 5(45), 29127-29139 (2020). [Open Access]

Henkel, J., Buchheim-Dieckow, K., Castro, J. P., Laeger, T., Wardelmann, K., Kleinridders, A., Johrens, K., Puschel, G. P.: Reduced Oxidative Stress and Enhanced FGF21 Formation in Livers of Endurance-Exercised Rats with Diet-Induced NASH. Nutrients 11(11): 15 (2019). [Open Access]

Klein, C., Jonas, W., Wiedmer, P., Schreyer, S., Akjüz, L., Spranger, J., Hellweg, R., Steiner, B.: High-fat diet and physical exercise differentially modulate adult neurogenesis in the mouse hypothalamus. Neuroscience 400, 146-156 (2019).

Neumann, A., Schindler, M., Olofsson, D., Wilhelmi, I., Schürmann, A., Heyd, F.: Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway. J. Cell Sci. 132:jcs230201 (2019).

Rabasa, C., Askevik, K., Schéle, E., Hu, M., Vogel, H., Dickson, S. L.: Divergent metabolic effects of acute versus chronic repeated forced swim stress in the rat. Obesity 27, 427-433 (2019). [Open Access]

Song, K., Gras, C., Capin, G., Gimber, N., Lehmann, M., Mohd, S., Puchkov, D., Rödiger, M., Wilhelmi, I., Daumke, O., Schmoranzer, J., Schürmann, A., Krauss, M.: A SEPT1-based scaffold is required for Golgi integrity and function. J. Cell Sci. 132(3): jcs225557 (2019). [Open Access]

Sztul, E., Chen, P. W., Casanova, J. E., Cherfils, J., Dacks, J. B., Lambright, D. G., Lee, F. S., Randazzo, P. A., Santy, L. C., Schürmann, A., Wilhelmi, I., Yohe, M. E., Kahn, R. A.: ARF GTPases and their GEFs and GAPs: concepts and challenges. Mol. Biol. Cell 30, 1249-1271 (2019).

Abderrahmani, A., Yengo, L., Caiazzo, R., Canouil, M., Cauchi, S., Raverdy, V., Plaisance, V., Pawlowski, V., Lobbens, S., Maillet, J., Rolland, L., Boutry, R., Queniat, G., Kwapich, M., Tenenbaum, M., Bricambert, J., Saussenthaler, S., Anthony, E., Jha, P., Derop, J., Sand, O., Rabearivelo, I., Leloire, A., Pigeyre, M., Daujat-Chavanieu, M., Gerbal-Chaloin, S., Dayeh, T., Lassailly, G., Mathurin, P., Staels, B., Auwerx, J., Schürmann, A., Postic, C., Schafmayer, C., Hampe, J., Bonnefond, A., Pattou, F., Froguel, P.: Increased hepatic PDGF-AA signaling mediates liver insulin resistance in obesity associated type 2 diabetes. Diabetes 67, 1310-1321 (2018). [Open Access]

Arnan, X., Andersen, A. N., Gibb, H., Parr, C. L., Sanders, N. J., Dunn, R. R., Angulo, E., Baccaro, F. B., Bishop, T. R., Boulay, R., Castracani, C., Cerdá, X., Del Toro, I., Delsinne, T., Donoso, D. A., Elten, E. K., Fayle, T. M., Fitzpatrick, M. C., Gómez, C., Grasso, D. A., Grossman, B. F., Guénard, B., Gunawardene, N., Heterick, B., Hoffmann, B. D., Janda, M., Jenkins, C. N., Klimes, P., Lach, L., Laeger, T., Leponce, M., Lucky, A., Majer, J., Menke, S., Mezger, D., Mori, A., Moses, J., Munyai, T. C., Paknia, O., Pfeiffer, M., Philpott, S. M., Souza, J. L. P., Tista, M., Vasconcelos, H. L., Retana, J.: Dominance-diversity relationships in ant communities differ with invasion. Glob. Chang. Biol. 24, 4614-4625 (2018). [Open Access]

Bégay, V., Baumeier, C., Zimmermann, K., Heuser, A., Leutz, A.: The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse. Sci. Rep. 8(1):8417 (2018). [Open Access]

Cedernaes, J., Schönke, M., Westholm, J. O., Mi, J., Chibalin, A., Voisin, S., Osler, M., Vogel, H., Hörnaeus, K., Dickson, S. L., Lind, S. B., Bergquist, J., Schiöth, H. B., Zierath, J. R., Benedict, C.: Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans. Sci. Adv. 4(8):eaar8590 (2018). [Open Access]

Gerst, F., Jaghutriz, B. A., Staiger, H., Schulte, A. M., Lorza-Gil, E., Kaiser, G., Panse, M., Haug, S., Heni, M., Schütz, M., Stadion, M., Schürmann, A., Marzetta, F., Ibberson, M., Sipos, B., Fend, F., Fleming, T., Nawroth, P. P., Königsrainer, A., Nadalin, S., Wagner, S., Peter, A., Fritsche, A., Richter, D., Solimena, M., Häring, H.-U., Ullrich, S., Wagner, R.: The expression of aldolase B in islets is negatively associated with insulin secretion in humans. J. Clin. Endocrinol. Metab. 103, 4373-4383 (2018).

Henkel, J., Alfine, E., Saín, J., Jöhrens, K., Weber, D., Castro, J. P., König, J., Stuhlmann, C., Vahrenbrink, M., Jonas, W., Kleinridders, A., Püschel, G. P.: Soybean oil-derived poly-unsaturated fatty acids enhance liver damage in NAFLD induced by dietary cholesterol. Nutrients 10(9): 1326 (2018). [Open Access]

Henkel, J., Coleman, C. D., Schraplau, A., Jöhrens, K., Weiss, T. S., Jonas, W., Schürmann, A., Püschel, G. P.: Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model. Sci. Rep. 8(1):16127 (2018). [Open Access]

Hesse, D., Trost, J., Schäfer, N., Schwerbel, K., Hoeflich, A., Schürmann, A., Brockmann, G. A.: Effect of adipocyte-derived IGF-I on adipose tissue mass and glucose metabolism in the Berlin Fat Mouse. Growth Factors 36, 78-88 (2018).

Hüser, S., Guth, S., Joost, H. G., Soukup, S. T., Köhrle, J., Kreienbrock, L., Diel, P., Lachenmeier, D. W., Eisenbrand, G., Vollmer, G., Nöthlings, U., Marko, D., Mally, A., Grune, T., Lehmann, L., Steinberg, P., Kulling, S. E.: Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation. Arch. Toxicol. 92, 2703-2748 (2018). [Open Access]

Khajavi, N., Finan, B., Kluth, O., Müller, T. D., Mergler, S., Schulz, A., Kleinau, G., Scheerer, P., Schürmann, A., Gudermann, T., Tschöp, M. H., Krude, H., DiMarchi, R. D., Biebermann, H.: An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation. Cell. Signal. 51, 13-22 (2018).

Panse, M., Kluth, O., Lorza-Gil, E., Kaiser, G., Mühlbauer, E., Schürmann, A., Häring, H. U., Ullrich, S., Gerst, F.: Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms. PLoS One 13(5):e0198016 (2018). [Open Access]

Schallschmidt, T., Lebek, S., Altenhofen, D., Damen, M., Schulte, Y., Knebel, B., Herwig, R., Rasche, A., Stermann, T., Kamitz, A., Hallahan, N., Jähnert, M., Vogel, H., Schürmann, A., Chadt, A., Al-Hasani, H.: Two novel candidate genes for insulin secretion identified by comparative genomics of multiple backcross mouse populations. Genetics 210, 1527-1542 (2018).

Werner, J.-U., Tödter, K., Xu, P., Lockhart, L., Jähnert, M., Gottmann, P., Schürmann, A., Scheja, L., Wabitsch, M., Knippschild, U.: Comparison of fatty acid and gene profiles in skeletal muscle in normal and obese C57BL/6J mice before and after blunt muscle injury. Front. Physiol. 9:19 (2018). [Open Access]

Xu, P., Werner, J.-U., Milerski, S., Hamp, C. M., Kuzenko, T., Jähnert, M., Gottmann, P., de Roy, L., Warnecke, D., Abaei, A., Palmer, A., Huber-Lang, M., Dürselen, L., Rasche, V., Schürmann, A., Wabitsch, M., Knippschild, U.: Diet-induced obesity affects muscle regeneration after murine blunt muscle trauma-A broad spectrum snalysis. Front. Physiol. 9:674 (2018). [Open Access]

Henkel, J., Coleman, C. D., Schraplau, A., Jӧhrens, K., Weber, D., Castro, J. P., Hugo, M., Schulz, T. J., Krämer, S., Schürmann, A., Püschel, G. P.: Induction of steatohepatitis (NASH) with insulin resistance in wildtype B6 mice by a western-type diet containing soybean oil and cholesterol. Mol. Med. 23, 70-82 (2017). [Open Access]

Hill, C. M., Laeger, T., Albarado, D. C., McDougal, D. H., Berthoud, H. R., Münzberg, H., Morrison, C. D.: Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints. Sci. Rep. 7:8209 (2017). [Open Access]

Wiemerslage, L., Islam, R., van der Kamp, C., Cao, H., Olivo, G., Ence-Eriksson, F., Castillo, S., Larsen, A. L., Bandstein, M., Dahlberg, L. S., Perland, E., Gustavsson, V., Nilsson, J., Vogel, H., Schürmann, A., Larsson, E. M., Rask-Andersen, M., Benedict, C., Schiöth, H. B.: A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels. Int. J. Obes. 41, 990-994 (2017).

Benedict, C., Vogel, H., Jonas, W., Woting, A., Blaut, M., Schürmann, A., Cedernaes, J.: Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals. Mol. Metab. 5, 1175-1186 (2016). [Open Access]

Cedernaes, J., Fanelli, F., Fazzini, A., Pagotto, U., Broman, J.-E., Vogel, H., Dickson, S. L., Schiöth, H. B., Benedict, C.: Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans. Psychoneuroendocrinology 74, 258-268 (2016). [Open Access]

Chubanov, V., Ferioli, S., Wisnowsky, A., Simmons, D. G., Leitzinger, C., Einer, C., Jonas, W., Shymkiv, Y., Bartsch, H., Braun, A., Akdogan, B., Mittermeier, L., Sytik, L., Torben, F., Jurinovic, V., van der Vorst, E. P., Weber, C., Yildirim, Ö. A., Sotlar, K., Schürmann, A., Zierler, S., Zischka, H., Ryazanov, A. G., Gudermann, T.: Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. eLife 5:e20914 (2016). [Open Access]

Heise, S., Trost, J., Arends, D., Wirth, E. K., Schäfer, N., Köhrle, J., Schürmann, A., Brockmann, G. A.: High variability of insulin sensitivity in closely related obese mouse inbred strains. Exp. Clin. Endocrinol. Diabetes 124, 519-528 (2016).

Klein, C., Jonas, W., Iggena, D., Empl, L., Rivalan, M., Wiedmer, P., Spranger, J., Hellweg, R., Winter, Y., Steiner, B.: Exercise prevents high-fat diet-induced impairment of flexible memory expression in the water maze and modulates adult hippocampal neurogenesis in mice. Neurobiol. Learn Mem. 131, 26-35 (2016).

Lietzow, J., Golchert, J., Homuth, G., Völker, U., Jonas, W., Köhrle, J.: 3,5-T2 alters murine genes relevant for xenobiotic, steroid and thyroid hormone metabolism. J. Mol. Endocrinol. 56, 311-323 (2016). [Open Access]

Müller, A., Niederstadt, L., Jonas, W., Yi, C. X., Meyer, F., Wiedmer, P., Fischer, J., Grötzinger, C., Schürmann, A., Tschöp, M., Kleinau, G., Grüters, A., Krude, H., Biebermann, H.: Ring finger protein 11 inhibits melanocortin 3 and 4 receptor signaling. Front. Endocrinol. (Lausanne) 7:109 (2016). [Open Access]

Rabasa, C., Winsa-Jörnulf, J., Vogel, H., Babaei, C. S., Askevik, K., Dickson, S. L.: Behavioral consequences of exposure to a high fat diet during the post-weaning period in rats. Horm. Behav. 85, 56-66 (2016). [Open Access]

Rask-Andersen, M., Bringeland, N., Nilsson, E. K., Bandstein, M., Olaya Búcaro, M., Vogel, H., Schürmann, A., Hogenkamp, P. S., Benedict, C., Schiöth, H. B.: Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition. Am. J. Clin. Nutr. 104, 518-525 (2016). [Open Access]

Schmidt, V., Schulz, N., Yan, X., Schürmann, A., Kempa, S., Kern, M., Blüher, M., Poy, M. N., Olivecrona, G., Willnow, T. E.: SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity. J. Clin. Invest. 126, 2706-2720 (2016). [Open Access]

Volckmar, A. L., Han, C. T., Pütter, C., Haas, S., Vogel, C. I., Knoll, N., Struve, C., Göbel, M., Haas, K., Herrfurth, N., Jarick, I., Grallert, H., Schürmann, A., Al-Hasani, H., Hebebrand, J., Sauer, S., Hinney, A.: Analysis of genes involved in body wWeight regulation by targeted re-sequencing. PLoS ONE 11(2):e0147904 (2016). [Open Access]

Wallbach, M., Duque Escobar, J., Babaeikelishomi, R., Stahnke, M.-J., Blume, R., Schröder, S., Kruegel, J., Maedler, K., Kluth, O., Kehlenbach, R. H., Miosge, N., Oetjen, E.: Distinct functions of the dual leucine zipper kinase depending on its subcellular localization. Cell. Signal. 28, 272-283 (2016).

Cedernaes, J., Osler, M. E., Voisin, S., Broman, J.-E., Vogel, H., Dickson, S. L., Zierath, J. R., Schiöth, H. B., Benedict, C.: Acute sleep loss induces tissue-specific epigenetic and transcriptional alterations to circadian clock genes in men. J. Clin. Endocrinol. Metab. 100, E1255-E1261 (2015).

Schering, L., Hoene, M., Kanzleiter, T., Jähnert, M., Wimmers, K., Klaus, S., Eckel, J., Weigert, C., Schürmann, A., Maak, S., Jonas, W., Sell, H.: Identification of novel putative adipomyokines by a cross-species annotation of secretomes and expression profiles. Arch. Physiol. Biochem. 121, 194-205 (2015).

Guth, S., Baum, M., Cartus, A. T., Diel, P., Engel, K. H., Engeli, B., Epe, B., Grune, T., Haller, D., Heinz, V., Hellwig, M., Hengstler, J. G., Henle, T., Humpf, H. U., Jäger, H., Joost, H. G., Kulling, S. E., Lachenmeier, D. W., Lampen, A., Leist, M., Mally, A., Marko, D., Nöthlings, U., Röhrdanz, E., Roth, A., Spranger, J., Stadler, R., Steinberg, P., Vieths, S., Wätjen, W., Eisenbrand, G.: Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value). Food Chem. Toxicol. 173:113632 (2023). [Open Access]

Bechmann, N., Eisenhofer, G.: Hypoxia-inducible Factor 2α: A Key Player in Tumorigenesis and Metastasis of Pheochromocytoma and Paraganglioma?. Exp. Clin. Endocrinol. Diabet. 130(05), 282-289 (2022). [Open Access]

Bornstein, S. R., Voit-Bak, K., Donate, T., Rodionov, R. N., Gainetdinov, R. R., Tselmin, S., Kanczkowski, W., Müller, G. M., Achleitner, M., Wang, J., Licinio, J., Bauer, M., Young, A. H., Thuret, S., Bechmann, N., Straube, R.: Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis?. Mol. Psych. 27, 34–37 (2022). [Open Access]

Wagner, R., Eckstein, S. S., Yamazaki, H., Gerst, F., Machann, J., Jaghutriz, B. A., Schürmann, A., Solimena, M., Singer, S., Königsrainer, A., Birkenfeld, A. L., Häring, H. U., Fritsche, A., Ullrich, S., Heni, M.: Metabolic implications of pancreatic fat accumulation. Nat. Rev. Endocrinol. 18(1), 43-54 (2022). [Open Access]

Jonas, W., Schürmann, A.: Genetic and epigenetic factors determining NAFLD risk. Mol. Metab. 50:101111 (2021). [Open Access]

Schell, M., Wardelmann, K., Kleinridders, A.: Untangling the effect of insulin action on brain mitochondria and metabolism. J. Neuroendocrinology 33(4):e12932 (2021). [Open Access]

Guth, S., Hüser, S., Roth, A., Degen, G., Diel, P., Edlund, K., Eisenbrand, G., Engel, K.-H., Epe, B., Grune, T., Heinz, V., Henle, T., Humpf, H.-U., Jäger, H., Joost, H.-G., Kulling, S. E., Lampen, A., Mally, A., Marchan, R., Marko, D., Mühle, E., Nitsche, M. A., Röhrdanz, E., Stadler, R., van Thriel, C., Vieths, S., Vogel, R. F., Wascher, E., Watzl, C., Nöthlings, U., Hengstler, J. G.: Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses. Arch. Tox. 94, 1375–1415 (2020). [Open Access]

Straube, R., Muller, G., Voit-Bak, K., Tselmin, S., Julius, U., Schatz, U., Rietzsch, H., Reichmann, H., Chrousos, G. P., Schürmann, A., Jarc, L., Ziemssen, T., Siepmann, T., Bornstein, S. R.: Metabolic and Non-Metabolic Peripheral Neuropathy: Is there a Place for Therapeutic Apheresis?. Horm Metab Res 51, 779-784 (2019).

Fruhwürth, S., Vogel, H., Schürmann, A., Williams, K. J.: Novel insights into how overnutrition disrupts the hypothalamic actions of leptin. Front. Endocrinol. 9:89 (2018). [Open Access]

Klaus, S., Pfeiffer, A. F. H., Boeing, H., Laeger, T., Grune, T.: The protein paradox: how much dietary protein is good for health?. Ernaehr. Umsch. 65, 42-47 (2018). [Open Access]

Kleinert, M., Clemmensen, C., Hofmann, S. M., Moore, M. C., Renner, S., Woods, S. C., Huypens, P., Beckers, J., Hrabe de Angelis, M., Schürmann, A., Bakhti, M., Klingenspor, M., Heiman, M., Cherrington, A. D., Ristow, M., Lickert, H., Wolf, E., Havel, P. J., Müller, T. D., Tschöp, M. H.: Animal models of obesity and diabetes mellitus. Nat. Rev. Endocrinol. 14, 140-162 (2018).

Schürmann, A.: Diabetes Mellitus. In: Offermanns, S., Rosenthal, W. (eds.) Encyclopedia of Molecular Pharmacology (Chapter 48-1) (2021).

Eisenbrand, G., Baum, M., Cartus, A. T., Diel, P., Engel, K.-H., Engeli, B., Epe, B., Grune, T., Guth, S., Haller, D., Heinz, V., Hellwig, M., Hengstler, J. G., Henle, T., Humpf, H.-U., Jäger, H., Joost, H.-G., Kulling, S., Lachenmeier, D. W., Lampen, A., Leist, M., Mally, A., Marko, D., Nöthlings, U., Röhrdanz, E., Roth, A., Spranger, J., Stadler, R., Vieths, S., Wätjen, W., Steinberg, P.: Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypothesis. Arch. Toxicol. 96(6), 1905-1914 (Editorial) (2022).

Fritsche, A., Szendrödi, J., Schürmann, A.: Intermittent Fasting - Mechanisms and Clinical Usefulness. Front. Endocrinol. 12:757539 (Editorial) (2021). [Open Access]

Guth, S., Hüser, S., Roth, A., Degen, G., Diel, P., Edlund, K., Eisenbrand, G., Engel, K. H., Epe, B., Grune, T., Heinz, V., Henle, T., Humpf, H. U., Jäger, H., Joost, H. G., Kulling, S. E., Lampen, A., Mally, A., Marchan, R., Marko, D., Mühle, E., Nitsche, M. A., Röhrdanz, E., Stadler, R., van Thriel, C., Vieths, S., Vogel, R. F., Wascher, E., Watzl, C., Nöthlings, U., Hengstler, J. G.: Contribution to the ongoing discussion on fluoride toxicity. Arch. Toxicol. 95(7), 2571–2587 (Editorial) (2021). [Open Access]

Joost, H.-G.: Metformin – nichtglykämische Wirkungen. Diabetologe 17, 105–112 (2021). [Open Access]

Gässler, A., Quiclet, C., Kluth, O., Gottmann, P., Schwerbel, K., Helms, A., Stadion, M., Wilhelmi, I., Jonas, W., Ouni, M., Mayer, F., Spranger, J., Schürmann, A., Vogel, H.: Overexpression of Gjb4 impairs cell proliferation and insulin secretion in primary islet cells. Mol. Met. 41:101042, (Brief Communication) (2020). [Open Access]

Stadion, M., Schürmann, A.: Intermittierendes Fasten – Was gibt es Neues aus der Wissenschaft?. Diabetologe (2020). [Open Access]

Rångtell, F. H., Schmidt, F., Würfel, J., Karamchedu, S., Andersson, P., Vogel, H., Benedict, C.: Morning ezymatic activity of DPP-4 is differentially altered by sleep loss in women and men. Diabetes Care 41, e10–e11 (Letter) (2018).

Joost, H. G.: The role of dual leucine zipper kinase (DLK) in β-cell apoptosis: a potential target for the prevention and treatment of type 2 diabetes?: Commentary to: Börchers et al., TNF-α induced DLK activation contributes to apoptosis in the β-cell line HIT. Naunyn Schmiedebergs Arch. Pharmacol. 390, 767-768 (Editorial) (2017).

Schürmann, A.: Verleihung des Werner-Creutzfeldt-Preises 2016: Neue Befunde zur Pathophysiologie des Typ-2-Diabetes [Werner-Creutzfeldt Award 2016: Novel findings on the pathophysiology of type 2 diabetes]. Diabetol. Stoffw. 11, 294-297 (2016).