Research Topics

  • Biomarker
  • Oxidative Stress
  • Micronutrients
  • Methylhistidine
  • Nutrition and Muscle Function in Aging
  • Frailty
  • Sarcopenia

Key Publications

Weber, D., Kochlik, B., Stuetz, W., Dollé, M.E.T., Jansen, E.H.J.M., Grubeck-Loebenstein, B., Debacq-Chainiaux, F., Bernhardt, J., Gonos, E.S., Capri, M., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Bürkle, A. and Grune, T.: Medication intake is associated with lower plasma carotenoids and higher fat-soluble vitamins in the cross-sectional MARK-AGE Study in older individuals. J. Clin. Med. 9(7):2072 (2020).

Bartolomaeus, T. U. P., Birkner, T., Bartolomaeus, H., Lober, U., Avery, E. G., Mahler, A., Weber, D., Kochlik, B., Balogh, A., Wilck, N., Boschmann, M., Muller, D. N., Marko, L., Forslund, S. K.: Quantifying Technical Confounders in Microbiome Studies. Cardiovasc Res in press (E-pub ahead of print) (2020).

Weber, D*., Kochlik, B.*, Demuth, I., Steinhagen-Thiessen, E., Grune, T., Norman, K.: Plasma carotenoids, tocopherols and retinol - Association with age in the Berlin Aging Study II. Redox Biol 32, 101461 (2020). *contributed equally.

Kochlik, B., Stuetz, W., Pérès, K., Pilleron, S., Féart, C., García García, F. J., Bandinelli, S., Gomez-Cabrero, D., Rodriguez-Mañas, L., Grune, T., Weber, D.: Associations of fat-soluble micronutrients and redox biomarkers with frailty status in the FRAILOMIC initiative. J. Cachexia Sarcopenia Muscle 10(6), 1339-1346 (2019).

Castaño-Martinez, T., Schumacher, F., Schumacher, S., Kochlik, B., Weber, D., Grune, T., Biemann, R., McCann, A., Abraham, K., Weikert, C., Kleuser, B., Schürmann, A., Laeger, T.: Methionine restriction prevents onset of type 2 diabetes in NZO mice. FASEB J. 33, 7092–7102 (2019).

Kochlik, B., Stuetz, W., Pérès, K., Féart, C., Tegner, J., Rodriguez-Mañas, L., Grune, T., Weber, D.: Associations of plasma 3-methylhistidine with frailty status in French cohorts of the FRAILOMIC initiative. J. Clin. Med. 8(7):1010 (2019).

Pinchuk, I., Weber, D., Kochlik, B., Stuetz, W., Toussaint, O., Debacq-Chainiaux, F., Dollé, M. E. T., Jansen, E. H. J. M., Gonos, E. S., Sikora, E., Breusing, N., Gradinaru, D., Sindlinger, T., Moreno-Villanueva, M., Bürkle, A., Grune, T., Lichtenberg, D.: Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study. Redox Biol. 24:101204 (2019).

Kochlik, B., Gerbracht, C., Grune, T., Weber, D.: The influence of dietary habits and meat consumption on plasma 3-methylhistidine - A potential marker for muscle protein turnover. Mol. Nutr. Food Res. 62(9): 1701062 (2018).

Höhn, A., Weber, D., Jung, T., Ott, C., Hugo, M., Kochlik, B., Kehm, R., König, J.Grune, T., Castro, J. P.: Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence. Redox Biol. 11, 482-501 (2017).

Kochlik, B., Grune, T., Weber, D.: New findings of oxidative stress biomarkers in nutritional research. Curr. Opin. Clin. Nutr. Metab. Care 20, 349-359 (2017).