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Status: 22.05.2019 07:27:07

Heart Attack and Stroke Risk Also Elevated in Women with Obesity Who Are Metabolically Healthy

Research highlight 31.05.2018

Women with obesity are at increased risk of cardiovascular disease, even if they are considered to be metabolically healthy. Moreover, women of normal weight are at risk of heart attack or stroke if they suffer from a metabolic disease such as diabetes or high blood pressure. These are the results of an analysis conducted by scientists of the German Institute of Human Nutrition (DIfE), Harvard University and University Hospital Tübingen based on 90,257 data records of the Nurses‘ Health Study, a large U.S. cohort study. Obesity therefore represents a serious risk of disease, regardless of whether one has had no metabolic abnormalities for years. There is still no clear evidence that there is a subgroup of people with obesity who do not have an increased risk. It is important to maintain metabolic health through a healthy lifestyle and a healthy diet in the long term – regardless of whether you are normal-weight or overweight.

Reference: Eckel N, Li Y, Kuxhaus O, Stefan N, Hu FB, Schulze MB. Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease risk across BMI categories in 90 257 women (the Nurses’ Health Study): 30 year follow-up from a prospective cohort study. Lancet Diabetes Endocrinol 2018.

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