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Abteilung Klinische Ernährung (KLE)

Publikationen

Anzahl: 341

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Abteilung Klinische Ernährung

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Honsek, C., Kabisch, S., Kemper, M., Gerbracht, C., Arafat, A. M., Birkenfeld, A. L., Dambeck, U., Osterhoff, M. A., Weickert, M. O., Pfeiffer, A. F. H.: Fibre supplementation for the prevention of type 2 diabetes and improvement of glucose metabolism: the randomised controlled Optimal Fibre Trial (OptiFiT). Diabetologia 61, 1295-1305 (Open Access) (2018).

Kabisch, S., Bäther, S., Dambeck, U., Kemper, M., Gerbracht, C., Honsek, C., Sachno, A., Pfeiffer, A. F. H.: Liver fat scores moderately reflect interventional changes in liver fat content by a low-fat diet but not by a low-carb diet. Nutrients 10(2): 157 (Open Access) (2018).

Kochlik, B., Gerbracht, C., Grune, T., Weber, D.: The influence of dietary habits and meat consumption on plasma 3-methylhistidine - A potential marker for muscle protein turnover. Mol. Nutr. Food Res. 62(9): 1701062 (Open Access) (2018).

Markova, M., Hornemann, S., Sucher, S., Wegner, K., Pivovarova, O., Rudovich, N., Thomann, R., Schneeweiss, R., Rohn, S., Pfeiffer, A. F. H.: Rate of appearance of amino acids after a meal regulates insulin and glucagon secretion in patients with type 2 diabetes: a randomized clinical trial. Am. J. Clin. Nutr. 108, 279-291 (2018).

Schüler, R., Seebeck, N., Osterhoff, M. A., Witte, V., Flöel, A., Busjahn, A., Jais, A., Brüning, J. C., Frahnow, T., Kabisch, S., Pivovarova, O., Hornemann, S., Kruse, M., Pfeiffer, A. F. H.: VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: consequences for cognitive function in humans. Mol. Metab. 11, 129-136 (Open Access) (2018).

Tacke, C., Aleksandrova, K., Rehfeldt, M., Murahovschi, V., Markova, M., Kemper, M., Hornemann, S., Kaiser, U., Honig, C., Gerbracht, C., Kabisch, S., Hörbelt, T., Ouwens, D. M., Weickert, M. O., Boeing, H., Pfeiffer, A. F. H., Pivovarova, O., Rudovich, N.: Assessment of circulating Wnt1 inducible signalling pathway protein 1 (WISP-1)/CCN4 as a novel biomarker of obesity. J. Cell Commun. Signal. 12, 539-548 (2018).

Weickert, M. O., Hattersley, J. G., Kyrou, I., Arafat, A. M., Rudovich, N., Roden, M., Nowotny, P., von Loeffelholz, C., Matysik, S., Schmitz, G., Pfeiffer, A. F. H.: Effects of supplemented isoenergetic diets varying in cereal fiber and protein content on the bile acid metabolic signature and relation to insulin resistance. Nutr. Diabetes 8:11 (Open Access) (2018).

Assefa, B., Mahmoud, A. M., Pfeiffer, A. F. H., Birkenfeld, A. L., Spranger, J., Arafat, A. M.: Insulin-like growth factor (IGF) binding protein-2, independently of IGF-1, induces GLUT-4 translocation and glucose uptake in 3T3-L1 adipocytes. Oxid. Med. Cell. Longev. 2017: 3035184 (Open Access) (2017).

Eichelmann, F., Rudovich, N., Pfeiffer, A. F., Schulze, M. B., Giuseppe, R. D., Boeing, H., Aleksandrova, K.: Novel adipokines: methodological utility in human obesity research. Int. J. Obes. 41, 976-981 (2017).

Frahnow, T., Osterhoff, M. A., Hornemann, S., Kruse, M., Surma, M. A., Klose, C., Simons, K., Pfeiffer, A. F. H.: Heritability and responses to high fat diet of plasma lipidomics in a twin study. Sci. Rep. 7(1):3750 (Open Access) (2017).

Kessler, K., Hornemann, S., Petzke, K. J., Kemper, M., Kramer, A., Pfeiffer, A. F. H., Pivovarova, O., Rudovich, N.: The effect of diurnal distribution of carbohydrates and fat on glycaemic control in humans: a randomized controlled trial. Sci. Rep. 7: 44170 (Open Access) (2017).

Markova, M., Pivovarova, O., Hornemann, S., Sucher, S., Frahnow, T., Wegner, K., Machann, J., Petzke, K. J., Hierholzer, J., Lichtinghagen, R., Herder, C., Carstensen-Kirberg, M., Roden, M., Rudovich, N., Klaus, S., Thomann, R., Schneeweiss, R., Rohn, S., Pfeiffer, A. F. H.: Isocaloric diets high in animal or plant protein reduce liver fat and inflammation in individuals with type 2 diabetes. Gastroenterology 152, 571–585 (2017).

Sarem, Z., Bumke-Vogt, C., Mahmoud, A. M., Assefa, B., Weickert, M. O., Adamidou, A., Bähr, V., Frystyk, J., Möhlig, M., Spranger, J., Lieske, S., Birkenfeld, A. L., Pfeiffer, A. F. H., Arafat, A. M.: Glucagon decreases IGF-1 bioactivity in humans, independently of insulin, by modulating its binding proteins. J. Clin. Endocrinol. Metab. 102, 3480-3490 (2017).

Schiess, S., Platz, S., Kemper, M., Schreiner, M., Mewis, I., Rohn, S., Bumke-Vogt, C., Pivovarova, O., Pfeiffer, A. F. H.: Oral administration of nasturtium affects peptide YY secretion in male subjects. Mol. Nutr. Food Res. 61(8), 1600886 (2017).

Schüler, R., Osterhoff, M. A., Frahnow, T., Möhlig, M., Spranger, J., Stefanovski, D., Bergman, R. N., Xu, L., Seltmann, A. C., Kabisch, S., Hornemann, S., Kruse, M., Pfeiffer, A. F. H.: Dietary fat intake modulates effects of a frequent ACE gene variant on glucose tolerance with association to type 2 diabetes. Sci. Rep. 7(1):9234 (Open Access) (2017).

Schüler. R., Osterhoff, M. A., Frahnow, T., Seltmann, A.-C., Busjahn, A., Kabisch, S., Xu, L., Mosig, A. S., Spranger, J., Möhlig, M., Hornemann, S., Kruse, M., Pfeiffer, A. F. H.: High-saturated-fat diet increases circulating angiotensin-converting enzyme, which is enhanced by the rs4343 polymorphism defining persons at risk of nutrient-dependent increases of blood pressure. J. Am. Heart. Assoc. 6:e004465 (Open Access) (2017).

Sucher, S., Markova, M., Hornemann, S., Pivovarova, O., Rudovich, N., Thomann, R., Schneeweiss, R., Rohn, S., Pfeiffer, A. F. H.: Comparison of the effects of diets high in animal or plant protein on metabolic and cardiovascular markers in type 2 diabetes - a randomized clinical trial. Diabetes Obes. Metab. 19, 944-952 (2017).

von Loeffelholz, C., Döcke, S., Lock, J. F., Lieske, S., Horn, P., Kriebel, J., Wahl, S., Singmann, P., de Las Heras Gala, T., Grallert, H., Raschzok, N., Sauer, I. M., Heller, R., Jahreis, G., Claus, R. A., Bauer, M., Stockmann, M., Birkenfeld, A. L., Pfeiffer, A. F. H.: Increased lipogenesis in spite of upregulated hepatic AMPK in human nonalcoholic fatty liver. Hepatol. Res. 47, 890-901 (2017).

von Loeffelholz, C., Pfeiffer, A. F. H., Lock, J. F., Lieske, S., Döcke, S., Murahovschi, V., Kriebel, J., de Las Heras Gala, T., Grallert, H., Rudovich, N., Stockmann, M., Spranger, J., Jahreis, G., Bornstein, S. R., Lau, G., Xu, A., Schulz-Menger, J., Exner, L., Haufe, S., Jordan, J., Engeli, S., Birkenfeld, A. L.: ANGPTL8 (betatrophin) is expressed in visceral adipose tissue and relates to human hepatic steatosis in two independent clinical collectives. Horm. Metab. Res. 49, 343-349 (2017).

Weitkunat, K., Schumann, S., Nickel, D., Hornemann, S., Petzke, K. J., Schulze, M. B., Pfeiffer, A. F. H., Klaus, S.: Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate. Am. J. Clin. Nutr. 105, 1544-1551 (2017).

Guzmán-Pérez, V., Bumke-Vogt, C., Schreiner, M., Mewis, I., Borchert, A., Pfeiffer, A. F. H.: Benzylglucosinolate derived isothiocyanate from Tropaeolum majus reduces gluconeogenic gene and protein expression in human cells. PLoS ONE 11(9):e0162397 (Open Access) (2016).

Kruse, M., Keyhani-Nejad, F., Isken, F., Nitz, B., Kretschmer, A., Reischl, E., de Las Heras Gala, T., Osterhoff, M. A., Grallert, H., Pfeiffer, A. F. H.: High-fat diet during mouse pregnancy and lactation targets GIP-regulated metabolic pathways in adult male offspring. Diabetes 65, 574-584 (Open Access) (2016).

Pivovarova, O., Gögebakan, Ö., Sucher, S., Groth, J., Murahovschi, V., Kessler, K., Osterhoff, M., Rudovich, N., Kramer, A., Pfeiffer, A. F. H.: Regulation of the clock gene expression in human adipose tissue by weight loss. Int. J. Obes. 40, 899-906 (2016).

Rudovich, N., Pivovarova, O., Bernigau, W., Sparwasser, A., Tacke, C., Murahovshi, V., Mertes, G., Birkenfeld, A. L., Bergmann, A., Weickert, M. O., Pfeiffer, A. F. H.: Modulation of circulating vasoactive peptides and extracellular matrix proteins are two novel mechanisms in the cardioprotective action of acarbose. Minerva Endocrinol. 41, 456-468 (Open Access) (2016).

von Loeffelholz, C., Horn, P., Birkenfeld, A. L., Claus, R. A., Metzing, B. U., Döcke, S., Jahreis, G., Heller, R., Hoppe, S., Stockmann, M., Lock, J. F., Rieger, A., Weickert, M. O., Settmacher, U., Rauchfuß, F., Pfeiffer, A. F. H., Bauer, M., Sponholz, C.: Fetuin A is a predictor of liver fat in preoperative patients with nonalcoholic fatty liver disease. J. Invest. Surg. 29, 266-274 (2016).

Gögebakan, Ö., Osterhoff, M. A., Schüler, R., Pivovarova, O., Kruse, M., Seltmann, A.-C., Mosig, A. S., Rudovich, N., Nauck, M., Pfeiffer, A. F. H.: GIP increases adipose tissue expression and blood levels of MCP-1 in humans and links high energy diets to inflammation: a randomised trial. Diabetologia 58, 1759-1768 (2015).

Keyhani-Nejad, F., Irmler, M., Isken, F., Wirth, E. K., Beckers, J., Birkenfeld, A. L., Pfeiffer, A. F. H.: Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice. Diabetologia 58, 374-383 (2015).

Kruse, M., von Loeffelholz, C., Hoffmann, D., Pohlmann, A., Seltmann, A.-C., Osterhoff, M., Hornemann, S., Pivovarova, O., Rohn, S., Jahreis, G., Pfeiffer, A. F. H.: Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men. Mol. Nutr. Food Res. 59, 507-519 (2015).

Lubura ,M., Hesse, D., Kraemer, M., Hallahan, N., Schupp, M., von Loeffelholz, C., Kriebel, J., Rudovich, N. N., Pfeiffer, A., John, C., Scheja, L., Heeren, J., Koliaki, C., Roden, M., Schürmann, A.: Diabetes prevalence in NZO females depends on estrogen action on liver fat content. Am. J. Physiol./Endocrinol. Metab. 309, E968-E980 (Open Access) (2015).

Murahovschi, V., Pivovarova, O., Ilkavets, I., Dmitrieva, R. M., Döcke, S., Keyhani-Nejad, F., Gögebakan, Ö., Osterhoff, M., Kemper, M., Hornemann, S., Markova, M., Klöting, N., Stockmann, M., Weickert, M. O., Lamounier-Zepter, V., Neuhaus, P., Konradi, A., Dooley, S., von Loeffelholz, C., Blüher, M., Pfeiffer, A. F. H., Rudovich, N.: WISP1 is a novel adipokine linked to inflammation in obesity. Diabetes 64, 856-866 (Open Access) (2015).

Pivovarova, O., Hornemann, S., Weimer, S., Lu, Y., Murahovschi, V., Zhuk, S., Seltmann, A.-C., Malashicheva, A., Kostareva, A., Kruse, M., Busjahn, A., Rudovich, N., Pfeiffer, A. F. H.: Regulation of nutrition-associated receptors in blood monocytes of normal weight and obese humans. Peptides 65, 12-19 (2015).

Pivovarova, O., Jürchott, K., Rudovich, N., Hornemann, S., Ye, L., Möckel, S., Murahovschi, V., Kessler, K., Seltmann, A.-C., Maser-Gluth, C., Mazuch, J., Kruse, M., Busjahn, A., Kramer, A., Pfeiffer, A. F. H.: Changes of dietary fat and carbohydrate content alter central and peripheral clock in humans. J. Clin. Endocrinol. Metab. 100, 2291-2302 (2015).

Pivovarova, O., von Loeffelholz, C., Ilkavets, I., Sticht, C., Zhuk, S., Murahovschi, V., Lukowski, S., Döcke, S., Kriebel, J., de Las Heras Gala, T., Malashicheva, A., Kostareva, A., Lock, J. F., Stockmann, M., Grallert, H., Gretz, N., Dooley, S., Pfeiffer, A. F. H., Rudovich, N.: Modulation of insulin degrading enzyme activity and liver cell proliferation. Cell Cycle 14, 2293-2300 (Open Access) (2015).

Rudovich, N., Pivovarova, O., Gögebakan, Ö., Sparwasser, A., Doehner, W., Anker, S. D., Arafat, A. M., Bergmann, A., Nauck, M. A., Pfeiffer, A. F. H.: Effect of exogenous intravenous administrations of GLP-1 and/or GIP on circulating pro-atrial natriuretic peptide in subjects with different stages of glucose tolerance. Diabetes Care 38(1):e7-8 (2015).

Arafat, A. M., Kaczmarek, P., Skrzypski, M., Pruszyńska-Oszmałek, E., Kołodziejski, P., Adamidou, A., Ruhla, S., Szczepankiewicz, D., Sassek, M., Billert, M., Wiedenmann, B., Pfeiffer, A. F. H., Nowak, K. W., Strowski, M. Z.: Glucagon regulates orexin A secretion in humans and rodents. Diabetologia 57, 2108–2116 (2014).

Bumke-Vogt, C., Osterhoff, M. A., Borchert, A., Guzman-Perez, V., Sarem, Z., Birkenfeld, A. L., Bähr, V., Pfeiffer, A. F. H.: The flavones apigenin and luteolin induce FOXO1 translocation but inhibit gluconeogenic and lipogenic gene expression in human cells. PLoS ONE 9(8): e104321 (Open Access) (2014).

Geillinger, K. E., Rathmann, D., Köhrle, J., Fiamoncini, J., Daniel, H., Kipp, A. P.: Hepatic metabolite profiles in mice with a suboptimal selenium status. J. Nutr. Biochem. 25, 914-922 (2014).

Hattersley, J. G., Pfeiffer, A. F. H., Roden, M., Petzke, K.-J., Hoffmann, D., Rudovich, N. N., Randeva, H. S., Vatish, M., Osterhoff, M., Goegebakan, Ö., Hornemann, S., Nowotny, P., Machann, J., Hierholzer, J., von Loeffelholz, C., Möhlig, M., Arafat, A. M., Weickert, M. O.: Modulation of amino acid metabolic signatures by supplemented isoenergetic diets differing in protein and ceral fiber content. J. Clin. Endocrinol. Metab. 99, E2599-E2609 (2014).

Kessler, K., Pivovarova, O., Pfeiffer, A. F. H.: Zirkadiane Uhren und Energiestoffwechsel: Implikationen für die Gesundheit [Circadian clocks and energy metabolism: implications for health]. Dtsch. Med. Wochenschr. 139, 684-686 (2014).

Weimer, S., Priebs, J., Kuhlow, D., Groth, M., Priebe, S., Mansfeld, J., Merry, T. L., Dubuis, S., Laube, B., Pfeiffer, A. F., Schulz, T. J., Guthke, R., Platzer, M., Zamboni, N., Zarse, K., Ristow, M.: D-Glucosamine supplementation extends life span of nematodes and of ageing mice. Nat. Commun. 5:3563 (Open Access) (2014).

Arafat, A. M., Weickert, M. O., Adamidou, A., Otto, B., Perschel, F. H., Spranger, J., Möhlig, M., Pfeiffer, A. F. H.: The impact of insulin-independent, glucagon-induced suppression of total ghrelin on satiety in obesity and type 1 diabetes mellitus. J. Clin. Endocrinol. Metab. 98, 4133-4142 (2013).

Brandstädt, S., Schmeisser, K., Zarse, K., Ristow, M.: Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner. Aging 5, 270-275 (2013).

Döcke, S., Lock, J. F., Birkenfeld, A. L., Hoppe, S., Lieske, S., Rieger, A., Raschzok, N., Sauer, I. M., Florian, S., Osterhoff, M. A., Heller, R., Herrmann, K., Lindenmüller, S., Horn, P., Bauer, M., Weickert, M. O., Neuhaus, P., Stockmann, M., Möhlig, M., Pfeiffer, A. F. H., von Loeffelholz, C.: Elevated hepatic chemerin mRNA expression in human non-alcoholic fatty liver disease. Eur. J. Endocrinol. 169, 547-557 (2013).

Müller, M. F., Florian, S., Pommer, S., Osterhoff, M., Esworthy, R. S., Chu, F.-F., Brigelius-Flohé, R., Kipp, A. P.: Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development. PLoS ONE 8(8): e72055 (2013).

Pivovarova, O., Bernigau, W., Bobbert, T., Isken, F., Möhlig, M., Spranger, J., Weickert, M. O., Osterhoff, M., Pfeiffer, A. F. H., Rudovich, N.: Hepatic insulin clearance is closely related to metabolic syndrome components. Diabetes Care 36, 3779-3785 (2013).

Schmeisser, K., Mansfeld, J., Kuhlow, D., Weimer, S., Priebe, S., Heiland, I., Birringer, M., Groth, M., Segref, A., Kanfi, Y., Price, N. L., Schmeisser, S., Schuster, S., Pfeiffer, A. F. H., Guthke, R., Platzer, M., Hoppe, T., Cohen, H. Y., Zarse, K., Sinclair, D. A., Ristow, M.: Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide. Nat. Chem. Biol. 9, 693-700 (2013).

Schmeisser, S., Schmeisser, K., Weimer, S., Groth, M., Priebe, S., Fazius, E., Kuhlow, D., Pick, D., Einax, J. W., Guthke, R., Platzer, M., Zarse, K., Ristow, M.: Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension. Aging Cell 12, 508-517 (2013).

Stevanovic, D., Trajkovic, V., Müller-Lühlhoff, S., Brandt, E., Abplanalp, W., Bumke-Vogt, C., Liehl, B., Wiedmer, P., Janjetovic, K., Starcevic, V., Pfeiffer, A. F. H., Al-Hasani, H., Tschöp, M. H., Castañeda, T. R.: Ghrelin-induced food intake and adiposity depend on central mTORC1/S6K1 signaling. Mol. Cell. Endocrinol. 381, 280-290 (2013).

Gögebakan, Ö., Andres, J., Biedasek, K., Mai, K., Kühnen, P., Krude, H., Isken, F., Rudovich, N. , Osterhoff, M., Kintscher, U., Nauck, M., Pfeiffer, A. F. H., Spranger, J.: Glucose-dependent insulinotropic polypeptide reduces fat-specific expression and activity of 11β-hydroxysteroid dehydrogenase type 1 and inhibits release of free fatty acids. Diabetes 61, 292-300 (2012).

Hattersley, J. G., Möhlig, M., Roden, M., Arafat, A. M., v. Loeffelholz, C., Nowotny, P., Machann, J., Hierholzer, J., Osterhoff, M., Khan, M., Pfeiffer, A. F. H., Weickert, M. O.: Quantifying the improvement of surrogate indices of hepatic insulin resistance using complex measurement techniques. PLoS ONE 7(6):e39029 Open Access (2012).

Pivovarova, O., Gögebakan, Ö., Klöting, N., Sparwasser, A., Weickert, M. O., Haddad, I., Nikiforova, V. J., Bergmann, A., Kruse, M., Seltmann, A. C., Blüher, M., Pfeiffer, A. F. H., Rudovich, N.: Insulin up-regulates natriuretic peptide clearance receptor expression in the subcutaneous fat depot in obese subjects: a missing link between CVD risk and obesity?. J. Clin. Endocrinol. Metab. 97, E731-E739 (2012).

Pivovarova, O., Gögebakan, Ö., Osterhoff, M. A., Nauck, M., Pfeiffer, A. F. H., Rudovich, N.: In vivo effect of glucose-dependent insulinotropic peptide (GIP) on the gene expression of calcitonin peptides in human subcutaneous adipose tissue. Regul. Pept. 179, 29-32 (2012).

Rudovich, N., Pivovarova, O., Traberth, A., Sparwasser, A., Weickert, M. O., Bernigau, W., Birkenfeld, A. L., Arafat, A. M., Bergmann, A., Pfeiffer, A. F. H.: Acarbose treatment enhances mid-regional pro-atrial natriuretic peptide concentrations in non-diabetic individuals: further evidence for a common cardiometabolic pathway?. Diabetologia 55, 3392-3395 (2012).

Ruhla, S., Arafat, A. M., Osterhoff, M., Weickert, M. O., Mai, K., Spranger, J., Schöfl, C., Pfeiffer, A. F. H., Möhlig, M.: Levothyroxine medication is associated with adiposity independent of TSH. Exp. Clin. Endocrinol. Diabetes 120, 351-354 (2012).

Schiess, S., Cressy, P. J., Thomson, B. M.: Predictive modelling of interventions to improve iodine intake in New Zealand. Public Health Nutr. 15, 1932-1940 (2012).

Birkenfeld, A. L., Lee, H.-Y., Guebre-Egziabher, F., Alves, T. C., Jurczak, M. J., Jornayvaz, F. R., Zhang, D., Hsiao, J. J., Martin-Montalvo, A., Fischer-Rosinsky, A., Spranger, J., Pfeiffer, A. F., Jordan, J., Fromm, M. F., König, J., Lieske, S., Carmean, C. M., Frederick, D. W., Weismann, D., Knauf, F., Irusta, M. P., De Cabo, R., Helfand, S. L., Samuel, V. T., Shulman, G. I.: Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Cell Metab. 14, 184-195 (2011).

Birkenfeld, A. L., Lee, H.-Y., Majumdar, S., Jurzcak, M. J., Camporez, J. P., Jornayvaz, F. R., Frederick, D. W., Guigni, B., Kahn, M., Zhang, D., Weismann, D., Arafat, A. M., Pfeiffer, A. F., Lieske, S., Oyadomari, S., Ron, D., Samuel, V. T., Shulman, G. I.: Influence of the hepatic eukaryotic initiation factor 2α (eIF2α) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism. J. Biol. Chem. 286, 36163-36170 (2011).

Goehring, I., Sauter, N. S., Catchpole, G., Assmann, A., Shu, L., Zien, K. S., Moehlig, M., Pfeiffer, A. F. H., Oberholzer, J., Willmitzer, L., Spranger, J., Maedler, K.: Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets. Diabetologia 54, 2584-2594 (2011).

Gögebakan, Ö., Kohl, A., Osterhoff, M. A., van Baak, M. A., Jebb, S. A., Papadaki, A., Martinez, J. A., Handjieva-Darlenska, T., Hlavaty, P., Weickert, M. O., Holst, C., Saris, W. H. M., Astrup, A., Pfeiffer, A. F. H. on behalf of DiOGenes: Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors. The Diet, Obesity, and Genes (DiOGenes) Study: A Randomized, Controlled Trial. Circulation 124, 2829-2838 (2011).

Mai, K., Reinecke, F., Andres, J., Bobbert, T., Kraatz, J., Wudy, S. A., Hartmann, M. F., Maser-Gluth, C., Pfeiffer, A. F. H., Spranger, J.: Effects of hyperlipidaemia on glucocorticoid metabolism: results of a randomized controlled trial in healthy young women. Clin. Endocrinol. 74, 551-557 (2011).

Möhlig, M., Arafat, A. M., Osterhoff, M. A., Isken, F., Weickert, M. O., Spranger, J., Pfeiffer, A. F. H., Schöfl, C.: Androgen receptor CAG repeat length polymorphism modifies the impact of testosterone on insulin sensitivity in men. Eur. J. Endocrinol. 164, 1013-1018 (2011).

Pivovarova, O., Fisher, E., Dudziak, K., Ilkavets, I., Dooley, S., Slominsky, P., Limborska, S., Weickert, M. O., Spranger, J., Fritsche, A., Boeing, H., Pfeiffer, A. F. H., Rudovich, N.: A polymorphism within the connective tissue growth factor (CTGF) gene has no effect on non-invasive markers of beta-cell area and risk of type 2 diabetes. Dis. Markers 31, 241-246 (2011).

Rudovich, N. N., Nikiforova, V. J., Otto, B., Pivovarova, O., Gögebakan, Ö., Erban, A., Möhlig, M., Weickert, M. O., Spranger, J., Tschöp, M. H., Willmitzer, L., Nauck, M., Pfeiffer, A. F. H.: Metabolomic linkage reveals function interaction between glucose-dependent insulinotropic polypeptide and ghrelin in humans. Am. J. Physiol./Endocrinol. Metab. 301, E608-E617 (2011).

Rudovich, N. N., Weickert, M. O., Pivovarova, O., Bernigau, W., Pfeiffer, A. F. H.: Effects of acarbose treatment on markers of insulin sensitivity and systemic inflammation. Diabetes Technol. Ther. 13, 615-623 (2011).

Ruhla, S., Arafat, A. M., Weickert, M. O., Osterhoff, M., Isken, F., Spranger, J., Schöfl, C., Pfeiffer, A. F. H., Möhlig, M.: T3/rT3-ratio is associated with insulin resistance independent of TSH. Horm. Metab. Res. 43, 130-134 (2011).

Weickert, M. O., Arafat, A. M., Blaut, M., Alpert, C., Becker, N., Leupelt, V., Rudovich, N., Moehlig, M., Pfeiffer, A. F. H.: Changes in dominant groups of the gut microbiota do not explain cereal‑fiber induced improvement of whole‑body insulin sensitivity. Nutr. Metab. 8:90 (Open Access) (2011).

Weickert, M. O., Roden, M., Isken, F., Hoffmann, D., Nowotny, P., Osterhoff, M., Blaut, M., Alpert, C., Gögebakan, Ö., Bumke-Vogt, C., Mueller, F., Machann, J., Barber, T. M., Petzke, K. J., Hierholzer, J., Hornemann, S., Kruse, M., Illner, A.-K., Kohl, A., Loeffelholz, C. V., Arafat, A. M., Möhlig, M., Pfeiffer, A. F. H.: Effects of supplemented isoenergetic diets differing in cereal fiber and protein content on insulin sensitivity in overweight humans. Am. J. Clin. Nutr. 94, 459-471 (2011).

Zarse, K., Bossecker, A., Müller-Kuhrt, L., Siems, K., Hernandez, M. A., Berendsohn, W. G., Birringer, M., Ristow, M.: The phytochemical glaucarubinone promotes mitochondrial metabolism, reduces body fat, and extends lifespan of Caenorhabditis elegans. Horm. Metab. Res. 43, 241-243 (2011).

Arafat, A. M., Möhlig, M., Weickert, M. O., Schöfl, C., Spranger, J., Pfeiffer, A. F. H.: Improved insulin sensitivity, preserved beta cell function and improved whole-body glucose metabolism after low-dose growth hormone replacement therapy in adults with severe growth hormone deficiency: a pilot study. Diabetologia 53, 1304-1313 (2010).

Bobbert, T., Mai, K., Fischer-Rosinský, A., Osterhoff, M., Pfeiffer, A. F. H., Spranger, J.: Relation between physiological variation of renal function and carotid intima media thickness in non-diabetic individuals. J. Atheroscler. Thromb. 17, 242-248 (2010).

Bobbert, T., Mai, K., Fischer-Rosinský, A., Pfeiffer, A. F. H., Spranger, J.: A1C is associated with intima-media thickness in individuals with normal glucose tolerance. Diabetes Care 33, 203-204 (2010).

Bobbert, T., Raila, J., Schwarz, F., Mai, K., Henze, A., Pfeiffer, A. F. H., Schweigert, F. J., Spranger, J.: Relation between retinol, retinol-binding protein 4, transthyretin and carotid intima media thickness . Atherosclerosis 213, 549-551 (2010).

Drogan, D., Weikert, C., Dierkes, J., Klipstein-Grobusch, K., Buijsse, B., Möhlig, M., Pfeiffer, A. F. H., Pischon, T., Spranger, J., Boeing, H.: Plasma γ-glutamyltransferase, cysteinyl-glycine, and oxidized low-densitiy lipoprotein. A pathway associated with myocardial infarction risk?. Arterioscler. Thromb. Vasc. Biol. 30, 2053-2058 (2010).

Isken, F., Klaus, S., Osterhoff, M., Pfeiffer, A. F. H., Weickert, M. O.: Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice. J. Nutr. Biochem. 21, 278-284 (2010).

Isken, F., Klaus, S., Petzke, K.-J., Loddenkemper, C., Pfeiffer, A. F. H., Weickert, M. O.: Impairment of fat oxidation under high- vs. low-glycemic index diet occurs before the development of an obese phenotype. Am. J. Physiol./Endocrinol. Metab. 298, E287-E295 (2010).

Kuhlow, D., Florian, S., von Figura, G., Weimer, S., Schulz, N., Petzke, K. J., Zarse, K., Pfeiffer, A. F. H., Rudolph, K. L., Ristow, M.: Telomerase deficiency impairs glucose metabolism and insulin secretion. Aging 2, 650-658 (Open Access) (2010).

Kuhlow, D., Zarse, K., Voigt, A., Schulz, T. J., Petzke, K. J., Schomburg, L., Pfeiffer, A. F. H., Ristow, M.: Opposing effects of dietary sugar and saturated fat on cardiovascular risk factors and glucose metabolism in mitochondrially impaired mice. Eur. J. Nutr. 49, 417-427 (2010).

Rudovich, N., Möhlig, M., Otto, B., Pivovarova, O., Spranger, J., Weickert, M. O., Pfeiffer, A. F. H.: Effect of meglitinides on postprandial ghrelin secretion pattern in type 2 diabetes mellitus. Diabetes Technol. Ther. 12, 57-64 (2010).

Ruhla, S., Weickert, M. O., Arafat, A. M., Osterhoff, M., Isken, F., Spranger, J., Schöfl, C., Pfeiffer, A. F. H., Möhlig, M.: A high normal TSH is associated with the metabolic syndrome. Clin. Endocrinol. 72, 696-701 (2010).

Schulz, T. J., Westermann, D., Isken, F., Voigt, A., Laube, B., Thierbach, R., Kuhlow, D., Zarse, K., Schomburg, L., Pfeiffer, A. F. H., Tschöpe, C., Ristow, M.: Activation of mitochondrial energy metabolism protects against cardiac failure. Aging 2, 843-853 (2010).

Thierbach, R., Drewes, G., Fusser, M., Voigt, A., Kuhlow, D., Blume, U., Schulz, T. J., Reiche, C., Glatt, H., Epe, B., Steinberg, P., Ristow, M.: The Friedreich´s ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals. Biochem. J. 432, 165-172 (2010).

von Loeffelholz, C., Möhlig, M., Arafat, A. M., Isken, F., Spranger, J., Mai, K., Randeva, H. S., Pfeiffer, A. F. H., Weickert, M. O.: Circulating vaspin is unrelated to insulin sensitivity in a cohort of nondiabetic humans. Eur. J. Endocrinol. 162, 507-513 (2010).

Arafat, A. M., Weickert, M. O., Frystyk, J., Spranger, J., Schöfl, C., Möhlig, M., Pfeiffer, A. F. H.: The role of insulin-like growth factor (IGF) binding protein-2 in the insulin-mediated decrease in IGF-I bioactivity. J. Clin. Endocrinol. Metab. 94, 5093-5101 (2009).

Bobbert, T., Weicht, J., Mai, K., Möhlig, M., Pfeiffer, A. F. H., Spranger, J.: Acute hyperinsulinaemia and hyperlipidaemia modify circulating adiponectin and its oligomers. Clin. Endocrinol. 71, 507-511 (2009).

Isken, F., Weickert, M. O., Tschöp, M. H., Nogueiras, R., Möhlig, M., Abdelrahman, A., Klaus, S., Thorens, B., Pfeiffer, A. F. H. : Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice. Diabetologia 52, 2159-2168 (2009).

Kohl, A., Gögebakan, Ö., Möhlig, M., Osterhoff, M., Isken, F., Pfeiffer, A. F. H., Weickert, M. O.: Increased interleukin-10 but unchanged insulin sensitivity after 4 weeks of (1,3)(1,6)-β-glycan consumption in overweight humans. Nutr. Res. 29, 248-254 (2009).

Mai, K., Andres, J., Biedasek, K., Weicht, J., Bobbert, T., Sabath, M., Meinus, S., Reinecke, F., Möhlig, M., Weickert, M. O., Clemenz, M., Pfeiffer, A. F. H., Kintscher, U., Spuler, S., Spranger, J.: Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21. Diabetes 58, 1532-1538 (2009).

Pivovarova, O., Gögebakan, Ö., Pfeiffer, A. F. H., Rudovich, N.: Glucose inhibits the insulin-induced activation of the insulin-degrading enzyme in HepG2 cells. Diabetologia 52, 1656-1664 (2009).

Pivovarova, O., Nikiforova, V. J., Pfeiffer, A. F. H., Rudovich, N.: The influence of genetic variants in HHEX gene on insulin metabolism in the German MESYBEPO cohort. Diabetes Metab. Res. Rev. 25, 156-162 (2009).

Ristow, M., Zarse, K., Oberbach, A., Klöting, N., Birringer, M., Kiehntopf, M., Stumvoll, M., Kahn, C. R., Blüher, M.: Antioxidants prevent health-promoting effects of physical exercise in humans. Proc. Natl. Acad. Sci. 106, 8665-8670 (2009).

Rudovich, N., Pivovarova, O., Fisher, E., Fischer-Rosinksy, A., Spranger, J., Möhlig, M., Schulze, M. B., Boeing, H., Pfeiffer, A. F. H.: Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes. J. Mol. Med. 87, 1145-1151 (2009).

Weickert, M. O., Schöfl-Siegert, B., Arafat, A. M., Pfeiffer, A. F. H., Möhlig, M., Schöfl, C.: A reverse postural test as a screening tool for aldosterone-producing adenoma: a pilot study. Endocrine 36, 75-82 (2009).

Arafat, A. M., Möhlig, M., Weickert, M. O., Perschel, F. H., Purschwitz, J., Spranger, J., Strasburger, C. J., Schöfl, C., Pfeiffer, A. F. H.: Growth hormone response during oral glucose tolerance test: the impact of assay method on the estimation of reference values in patients with acromegaly and in healthy controls and the role of gender, age and body mass index. J. Clin. Endocrinol. Metab. 93, 1254-1262 (2008).

Assmann, A., Möhlig, M., Osterhoff, M., Pfeiffer, A. F. H., Spranger, J.: Fatty acids differentially modify the expression of urokinase type plasminogen activator receptor in monocytes. Biochem. Biophys. Res. Commun. 376, 196-199 (2008).

Fischer-Rosinsky, A., Fisher, E., Kovacs, P., Blüher, M., Möhlig, M., Pfeiffer, A. F. H., Boeing, H., Spranger, J.: Lack of association between the tagging SNP A+930->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations. PLoS ONE 3(12) (Open Access) (2008).

Fischer, A., Fisher, E., Möhlig, M., Schulze, M., Hoffmann, K., Weickert, M. O., Schueler, R., Osterhoff, M., Pfeiffer, A. F. H., Boeing, H., Spranger, J.: KCNJ11 E23K affects diabetes risk and is associated with the disposition index: Results of two independent German cohorts. Diabetes Care 31, 87-89 (2008).

Isken, F., Pfeiffer, A. F. H., Nogueiras, R., Osterhoff, M. A., Ristow, M., Thorens, B., Tschöp, M. H., Weickert, M. O.: Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice. Am. J. Physiol./Endocrinol. Metab. 295, E350-E355 (2008).

Mai, K., Bobbert, T., Reinecke, F., Andres, J., Maser-Gluth, C., Wudy, S. A., Möhlig, M., Weickert, M. O. , Hartmann, M. F., Schulte, H. M., Diederich, S., Pfeiffer, A. F. H., Spranger, J.: Intravenous lipid and heparin infusion-induced elevation in free fatty acids and triglycerides modifies circulating androgen levels in women: a randomized, controlled trial. J. Clin. Endocrinol. Metab. 93, 3900-3906 (2008).

Möhlig, M., Weickert, M. O., Ghadamgahi, E., Arafat, M. A., Spranger, J., Pfeifer, A. F. H., Schöfl, C.: Retinol-binding protein 4 is associated with insulin resistance, but appears unsuited for metabolic screening in women with polycystic ovary syndrome. Eur. J. Endocrinol. 158, 517-523 (2008).

Osterhoff, M. A., Heuer, S., Pfeiffer, M., Tasic, J., Kaiser, S., Isken, F., Spranger, J., Weickert, M. O. , Möhlig, M., Pfeiffer, A. F. H.: Identification of a functional protein kinase Cβ promoter polymorphism in humans related to insulin-resistance. Mol. Genet. Metab. 93, 210-215 (2008).

Weickert, M. O., Löffelholz, C. V., Arafat, M. A., Schöfl, C., Otto, B., Spranger, J., Möhlig, M., Pfeiffer, A. F. H.: Euglycemic hyperinsulinemia differentially modulates circulating total and acylated-ghrelin in humans. J. Endocrinol. Invest. 31, 119-124 (2008).

Weickert, M. O., Möhlig, M., Spranger, J., Schöfl, C., Loeffelholz, C. V., Riepl, R. L., Otto, B., Pfeiffer, A. F. H.: Effects of euglycemic hyperinsulinemia and lipid infusion on circulating cholecystokinin. J. Clin. Endocrinol. Metab. 93, 2328-2333 (2008).

Weikert, C., Westphal, S., Berger, K., Dierkes, J., Möhlig, M., Spranger, J., Rimm, E. B., Willich, S. N., Boeing, H., Pischon, T.: Plasma resistin levels and risk of myocardial infarction and ischemic stroke. J. Clin. Endocrinol. Metab. 93, 2647-2653 (2008).

Andres, J., Mai, K., Möhlig, M., Weickert, M. O., Bumke-Vogt, C., Diederich, S., Pfeiffer, A. F. H., Bähr, V., Spranger, J.: Cell-type specific regulation of the human 11beta-hydroxysteroid dehydrogenase type 1 promoter. Arch. Physiol. Biochem. 113, 110-115 (2007).

Bobbert, T., Wegewitz, U., Brechtel, L., Freudenberg, M., Mai, K., Möhlig, M., Diederich, S., Ristow, M., Rochlitz, H., Pfeiffer, A. F. H., Spranger, J.: Adiponectin oligomers in human serum during acute and chronic exercise: relation to lipid metabolism and insulin sensitivity. In. J. Sports Med. 28, 1-8 (2007).

Dierkes, J., Weikert, C., Klipstein-Grobusch, K., Westphal, S., Luley, C., Möhlig, M., Spranger, J., Boeing, H.: Plasma pyridoxal-5-phosphate and future risk of myocardial infarction in the European Prospective Investigation into Cancer and Nutrition Potsdam cohort. Am. J. Clin. Nutr. 86, 214-220 (2007).

Fisher, E., Nitz, I., Lindner, I., Rubin, D., Boeing, H., Möhlig, M., Hampe, J., Schreiber, S., Schrezenmeir, J., Döring, F.: Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort - Role of fat assimilation. Mol. Nutr. Food Res. 51, 185-191 (2007).

Fisher, E., Weikert, C., Klapper, M., Lindner, I., Möhlig, M., Spranger, J., Boeing, H., Schrezenmeir, J., Döring, F.: L-FABP T94A is associated with fasting triglycerides and LDL-cholesterol in women. Mol. Genet. Metab. 91, 278-284 (2007).

Garcia, A. L., Otto, B., Reich, S.-C., Weickert, M. O., Steiniger, J., Machowetz, A., Rudovich, N. N. , Möhlig, M., Katz, N., Speth, M., Meuser, F., Doerfer, J., Zunft, H.-J. F., Pfeiffer, A. F. H., Koebnick, C.: Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance. Eur. J. Clin. Nutr. 61, 334-341 (2007).

Gruendel, S., Garcia, A. L. , Otto, B., Wagner, K., Bidlingmaier, M., Burget, L., Weickert, M. O., Dongowski, G., Speth, M., Katz, N., Koebnick, C.: Increased acylated plasma ghrelin, but improved lipid profiles 24-h after consumption of carob pulp preparation rich in dietary fibre and polyphenols. Br. J. Nutr. 98, 1170-1177 (2007).

Gruendel, S., Otto, B., Garcia, A. L., Wagner, K., Mueller, C., Weickert, M. O., Heldwein, W., Koebnick, C.: Carob pulp preparation rich in insoluble dietary fibre and polyphenols increases plasma glucose and serum insulin responses in combination with a glucose load in humans. Br. J. Nutr. 98, 101-15 (2007).

Möhlig, M., Weickert, M. O., Ghadamgadai, E., Machlitt, A., Pfüller, B., Arafat, A. M., Pfeiffer, A. F. H., Schöfl, C.: Adipocyte fatty acid-binding protein is associated with markers of obesity, but is an unlikely link between obesity, insulin resistance, and hyperandrogenism in polycystic ovary syndrome women. Eur. J. Endocrinol. 157, 195-200 (2007).

Pischon, T., Möhlig, M., Hoffmann, K., Spranger, J., Weikert, C., Willich, S. N., Pfeiffer, A. F. H., Boeing, H.: Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels. Eur. J. Epidemiol. 22, 429-438 (2007).

Pomplun, D., Florian, S., Schulz, T., Pfeiffer, A. F. H., Ristow, M.,: Alterations of pancreatic beta-cell mass and islet number due to Ins2-controlled expression of Cre recombinase: RIP-Cre revisited; Part 2. Horm. Metab. Res. 39, 336-340 (2007).

Pomplun, D., Voigt, A., Schulz, T. J., Thierbach, R., Pfeiffer, A. F. H., Ristow, M.: Reduced expression of mitochondrial frataxin in mice exacerbates diet-induced obesity. Proc. Natl. Acad. Sci. 104, 6377-6381 (2007).

Rudovich, N., Kaiser, S., Engeli, S., Osterhoff, M., Gögebakan, Ö., Bluher, M., Pfeiffer, A. F. H.: GIP receptor mRNA expression in different fat tissue depots in postmenopausal non-diabetic women. Regul. Pept. 142, 138-145 (2007).

Schulz, T. J., Zarse, K., Voigt, A., Urban, N., Birringer, M., Ristow, M.: Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidating stress. Cell Metab. 6, 280-293 (2007).

Schulze, M. B., Hoffmann, K., Boeing, H., Linseisen, J., Rohrmann, S., Möhlig, M., Pfeiffer, A. F. H., Spranger, J., Thamer, C., Häring, H.-U., Fritsche, A., Joost, H.-G.: An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes. Diabetes Care 30, 510-515 (2007).

Weickert, M. O., von Loeffelholz, C., Roden, M., Chandramouli, V., Brehm, A., Nowotny, P., Osterhoff, M. A., Isken, F., Spranger, J., Landau, B. R., Pfeiffer, A. F. H., Möhlig, M.: A Thr94Ala mutation in human liver fatty acid-binding protein contributes to reduced hepatic glycogenolysis and blunted elevation of plasma glucose levels in lipid-exposed subjects. Am. J. Physiol./Endocrinol. Metab. 293, E1078-E1084 (2007).

Weikert, C., Dierkes, J., Hoffmann, K., Berger, K., Drogan, D., Klipstein-Grobusch, K., Spranger, J., Möhlig, M., Luley, C., Boeing, H.: B vitamin plasma levels and the risk of ischemic stroke and transient ischemic attack in a German cohort. Stroke 38, 2912-2918 (2007).

Arafat, A. M., Perschel, F. H., Otto, B., Weickert, M. O., Rochlitz, H., Schöfl, C., Spranger, J., Möhlig, M., Pfeiffer, A. F. H.: Glucagon suppression of ghrelin secretion is exerted at hypothalamus-pituitary level. J. Clin. Endocrinol. Metab. 91, 3528-3533 (2006).

Fisher, E., Li, Y., Burwinkel, B., Kühr, V., Hoffmann, K., Möhlig, M., Spranger, J., Pfeiffer, A., Boeing, H., Schrezenmeir, J., Döring, F.: Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort. Horm. Metab. Res. 38, 341-345 (2006).

Garcia, A. L., Steiniger, J., Reich, S, C., Weickert, M. O., Harsch, I., Machowetz, A., Mohlig, M., Spranger, J., Rudovich, N. N., Meuser, F., Doerfer, J., Katz, N., Speth, M., Zunft, H. J. F., Pfeiffer, A. H. F. , Koebnick, C.: Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance. Horm. Metab. Res. 38, 761-766 (2006).

Gruendel, S., Garcia, A. L., Otto, B., Mueller, C., Steiniger, J., Weickert, M. O., Speth, M., Katz, N., Koebnick, C.: Carob pulp preparation rich in insoluble dietary fiber and polyphenols enhances lipid oxidation and lowers postprandial acylated ghrelin in humans. J. Nutr. 136, 1533-1538 (2006).

Gruendel, S., Weickert, M. O., Garcia, A. L., Wagner, K., Pfeiffer, A. F. H., Harsch, I., Koebnick, C.: Serum resistin increases in a postprandial state during liquid meal challenge test in healthy human subjects. J. Endocrinol. Invest. 29, RC27-RC30 (2006).

Isken, F., Schulz, T. J., Weickert, M. O., Pfeiffer, A. F. H., Ristow, M.: Chemical inhibition of citrate metabolism alters body fat content in mice. Horm. Metab. Res. 38, 134-136 (2006).

Klipstein-Grobusch, K., Möhlig, M., Spranger, J., Hoffmann, K., Rodrigues, F. U. S., Sharma, A. M., Klaus, S., Pfeiffer, A. F. H., Boeing, H.: Interleukin-6 g.-174G>C promoter polymorphism is associated with obesity in the EPIC-Potsdam Study. Obesity 14, 14-18 (2006).

Koebnick, C., Wagner, K., Garcia, A. L., Gruendel, S., Lahmann, P. H., Weickert, M. O., Möhlig, M., Harsch, I. A., Einig, C., Speth, M., Katz, N., Trippo, U., Zunft, H. J. F.: Increase in serum resistin during weight loss in overweight subjects is related to lipid metabolism. Int. J. Obes. 30, 1097-1103 (2006).

Mai, K., Bobbert, T., Kullmann, V., Andres, J., Rochlitz, M., Osterhoff, M., Weickert, M. O., Bähr, V., Möhlig, M., Pfeiffer, A. F. H., Diederich, S., Spranger, J.: Free fatty acids increase androgen precursors in vivo. J. Clin. Endocrinol. Metab. 91, 1501-1507 (2006).

Mohan, R., Namsolleck, P., Lawson, P. A., Osterhoff, M., Collins, M. D., Alpert, C.-A., Blaut, M.: Clostridium asparagiforme sp. nov., isolated from a human faecal sample. Syst. Appl. Microbiol. 29, 292-299 (2006).

Möhlig, M., Flöter, A., Spranger, J., Weickert, M. O., Schill, T., Schlösser, H. W., Brabant, G., Pfeiffer, A. F. H., Selbig, J., Schöfl, C.: Predicting impaired glucose metabolism in women with polycystic ovary syndrome by decision tree modelling. Diabetologia 49, 2572-2579 (2006).

Möhlig, M., Freudenberg, M., Bobbert, T., Ristow, M., Rochlitz, H., Weickert, M. O., Pfeiffer, A. F. H., Spranger, J: Acetylsalicylic acid improves lipid-induced insulin resistance in healthy men. J. Clin. Endocrinol. Metab. 91, 964-967 (2006).

Möhlig, M., Jürgens, A., Spranger, J., Hoffmann, K., Weickert, M. O., Schlösser, H. W., Schill, T., Brabant, G., Schüring, A., Pfeiffer, A. F. H., Gromoll, J., Schöfl, C.: The androgen receptor CAG repeat modifies the impact of testosterone on insulin resistance in women with polycystic ovary syndrome. Eur. J. Endocrinol. 155, 127-130 (2006).

Möhlig, M., Spranger, J., Ristow, M., Pfeiffer, A. F. H., Schill, T., Schlösser, H. W., Moltz, L., Brabant, G., Schöfl, C.: Predictors of abnormal glucose metabolism in women with polycystic ovary syndrome. Eur. J. Endocrinol. 154, 295-301 (2006).

Schulz, T. J., Thierbach, R., Voigt, A., Drewes, G., Mietzner, B., Steinberg, P., Pfeiffer, A. F. H., Ristow, M.: Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth. J. Biol. Chem. 281, 977-981 (2006).

Spranger, J., Verma, S., Göhring, I., Bobbert, T., Seifert, J., Sindler, A. L., Pfeiffer, A., Hileman, S., Tschöp, M., Banks, W. A.: Adiponectin does not cross the blood-brain barrier but modifies cytokine expression of brain endothelial cells. Diabetes 55, 141-147 (2006).

Weickert, M. O., Möhlig, M., Schöfl, C., Arafat, A. M., Otto, B., Viehoff, H., Koebnick, C., Kohl, A., Spranger, J., Pfeiffer, A. F. H.: Cereal fiber improves whole-body insulin sensitivity in overweight and obese women. Diabetes Care 29, 775-780 (2006).

Weickert, M. O., Reimann, M., Otto, B., Hall, W. L., Vafeiadou, K., Hallund, J., Ferrari, M., Talbot, D., Branca, F., Bugel, S., Williams, S. M., Zunft, H.-J., Koebnick, C.: Soy isoflavones increase preprandial peptide YY (PYY), but have no effect on ghrelin and body weight in healthy postmenopausal women. J. Negat. Results Biomed. 5, Article 11 (Open Access) (2006).

Weickert, M. O., Spranger, J., Holst, J. J., Otto, B., Koebnick, C., Möhlig, M., Pfeiffer, A. F. H.: Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety. Br. J. Nutr. 96, 795-798 (2006).

Arafat, M. A., Otto, B., Rochlitz, H., Tschöp, M., Bähr, V., Möhlig, M., Diederich, S., Spranger, J., Pfeiffer, A. F. H.: Glucagon inhibits ghrelin secretion in humans. Eur. J. Endocrinol. 153, 397-402 (2005).

Bobbert, T., Brechtel, L., Mai, K., Otto, B., Maser-Gluth, C., Pfeiffer, A. F. H., Spranger, J., Diederich, S.: Adaption of the hypothalamic-pituitary hormones during intensive endurance training. Clin. Endocrinol. 63, 530-536 (2005).

Bobbert, T., Rochlitz, H., Wegewitz, U., Akpulat, S., Mai, K., Weickert, M. O., Möhlig, M., Pfeiffer, A. F. H., Spranger, J.: Changes of adiponectin oligomer composition by moderate weight reduction. Diabetes 54, 2712-2719 (2005).

Heidemann, C., Hoffmann, K., Spranger, J., Klipstein-Grobusch, K., Möhlig, M., Pfeiffer, A. F. H., Boeing, H.: A dietary pattern protective against type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study cohort. Diabetologia 48, 1126-1134 (2005).

Jürgens, H., Haass, W., Castaneda, T. R., Schürmann, A., Koebnick, C., Dombrowski, F., Otto, B., Nawrocki, A. R., Scherer, P. E., Spranger, J., Ristow, M., Joost, H.-G., Havel, P. J., Tschöp, M. : Consuming fructose-sweetened beverages increases body adiposity in mice. Obes. Res. 13, 1146-1156 (2005).

Kluth, D., Landes, N., Pfluger, P., Müller-Schmehl, K., Weiss, K., Bumke-Vogt, C., Ristow, M., Brigelius-Flohé, R.: Modulation of Cyp3a11 mRNA expression by α-tocopherol but not γ-tocotrienol in mice. Free Radic. Biol. Med. 38, 507-514 (2005).

Möhlig, M., Koebnick, C., Weickert, M. O., Lueder, W., Otto, B., Steiniger, J., Twilfert, M., Meuser, F., Pfeiffer, A. F. H., Zunft, H. J.: Arabinoxylan-enriched meal increases serum ghrelin levels in healthy humans. Horm. Metab. Res. 37, 303-308 (2005).

Rochlitz, H., Akpulat, S., Bobbert, T., Mai, K., Möhlig, M., Osterhoff, M., Weickert, M. O., Pfeiffer, A. F., Spranger, J. : Bedeutung von Biomarkern des metabolischen Syndroms bei Gewichtsreduktion. Dtsch. Med. Wochenschr. 130, 1061-1066 (2005).

Rudovich, N. N., Dick, D., Moehlig, M., Otto, B., Spranger, J., Rochlitz, H. J., Ristow, M., Tschoep, M., Pfeiffer, A. F. H.: Ghrelin is not suppressed in hyperglycemic clamps by gastric inhibitory polypeptide and arginine. Regul. Pept. 127, 95-99 (2005).

Thierbach, R., Schulz, T. J., Isken, F., Voigt, A., Mietzner, B., Drewes, G., von Kleist-Retzow, J.-C., Wiesner, R. J., Magnuson, M. A., Puccio, H., Pfeiffer, A. F. H., Steinberg, P., Ristow, M.: Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span, and tumor growth in mice. Hum. Mol. Genet. 14, 3857-3864 (2005).

Weickert, M. O., Mohlig, M., Koebnick, C., Holst, J. J., Namsolleck, P., Ristow, M., Osterhoff, M., Rochlitz, H., Rudovich, N., Spranger, J., Pfeiffer, A. F. H. : Impact of cereal fibre on glucose-regulating factors. Diabetologia 48, 2343-2353 (2005).

Diederich, S., Scholz, T., Eigendorff, E., Bumke-Vogt, Ch., Quinkler, M., Exner, P., Pfeiffer, A. F., Oelkers, W., Bahr, V.: Pharmacodynamics and pharmacokinetics of synthetic mineralocorticoids and glucocorticoids: receptor transactivation and prereceptor metabolism by 11β-hydroxysteroid-dehydrogenases. Horm. Metab. Res. 36, 423-429 (2004).

Grossmann, C., Scholz, T., Rochel, M., Bumke-Vogt, C., Oelkers, W., Pfeiffer, A. F., Diederich, S., Bähr, V.: Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties. Eur. J. Endocrinol. 151, 397-406 (2004).

Möhlig, M., Boeing, H., Spranger, J., Osterhoff, M., Kroke, A., Fisher, E., Bergmann, M. M., Ristow, M., Hoffmann, K., Pfeiffer, A. F. H.: Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes. J. Clin. Endocrinol. Metab. 89, 1885-1890 (2004).

Möhlig, M., Spranger, J., Osterhoff, M., Ristow, M., Pfeiffer, A. F. H., Schill, T., Schlösser, H. W., Brabant, G., Schöfl, C.: The polycystic ovary syndrome per se is not associated with increased chronic inflammation. Eur. J. Endocrinol. 150, 525-532 (2004).

Otto, B., Tschöp, M., Heldwein, W., Pfeiffer, A. F., Diederich, S.: Endogenous and exogenous glucocorticoids decrease plasma ghrelin in humans. Eur. J. Endocrinol. 151, 113-117 (2004).

Pomplun, D., Möhlig, M., Spranger, J., Pfeiffer, A. F. H., Ristow, M.: Elevation of blood glucose following anaesthetic treatment in C57BL/6 mice. Horm. Metab. Res. 36, 67-69 (2004).

Rudovich, N. N., Leyck Dieken, M. G., Rochlitz, H., Pfeiffer, A. F.: Enhancement of early- and late-phase insulin secretion and insulin sensitivity by the combination of repaglinide and metformin in type 2 diabetes mellitus. Exp. Clin. Endocrinol. Diabetes 112, 395-400 (2004).

Rudovich, N. N., Rochlitz, H. J., Pfeiffer, A. F. H.: Reduced hepatic insulin extraction in response to gastric inhibitory polypeptide compensates for reduced insulin secretion in normal-weight and normal glucose tolerant first-degree relatives of type 2 diabetic patients. Diabetes 53, 2359-2365 (2004).

Spranger, J., Möhlig, M., Wegewitz, U., Ristow, M., Pfeiffer, A. F. H., Schill, T., Schlösser, H. W., Brabant, G., Schöfl, C.: Adiponectin is independently associated with insulin sensitivity in women with polycystic ovary syndrome. Clin. Endocrinol. 61, 738-746 (2004).

Engeli, S., Feldpausch, M., Gorzelniak, K., Hartwig, F., Heintze, U., Janke, J., Möhlig, M., Pfeiffer, A. F., Luft, F. C., Sharma, A. M.: Association between adiponectin and mediators of inflammation in obese women. Diabetes 52, 942-947 (2003).

Fahrmann, M., Kaufhold, M., Pfeiffer, A. F., Seidler, U.: Protein kinase C-α attenuates cholinergically stimulated gastric acid secretion of rabbit parietal cells. Br. J. Pharmacol. 139, 545-554 (2003).

Kopp, R., Rothbauer, E., Mueller, E., Schildberg, F. W., Jauch, K. W., Pfeiffer, A.: Reduced survival of rectal cancer patients with increased tumor epidermal growth factor receptor levels. Dis. Colon Rectum 46(10), 1391-1399 (2003).

Kopp, R., Rothbauer, E., Ruge, M., Arnholdt, H., Spranger, J., Muders, M., Pfeiffer, D. G., Schildberg, F. W., Pfeiffer, A.: Clinical implications of the EGF receptor/ligand system for tumor progression and survival in gastrointestinal carcinomas: evidence for new therapeutic options. Recent Results Cancer Res. 162, 115-132 (2003).

Norris, A. W., Chen, L., Fisher, S. J., Szanto, I., Ristow, M., Jozsi, A. C., Hirshman, M. F., Rosen, E. D., Goodyear, L. J., Gonzalez, F. J., Spiegelman, B. M., Kahn, C. R.: Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J. Clin. Invest. 112, 608-618 (2003).

Osterhoff, M., Möhlig, M., Schwanstecher, M., Seufert, J., Ortmann, J., Schatz, H., Pfeiffer, A. F.: Ca2+/calmodulin-dependent protein kinase II δ2 regulates gene expression of insulin in INS-1 rat insulinoma cells. Cell Calcium 33, 175-184 (2003).

Ristow, M., Mulder, H., Pomplun, D., Schulz, T. J., Müller-Schmehl, K., Krause, A., Fex, M., Puccio, H., Müller, J., Isken, F., Spranger, J., Müller-Wieland, D., Magnuson, M. A., Möhlig, M., Koenig, M., Pfeiffer, A. F. H.: Frataxin deficiency in pancreatic islets causes diabetes due to loss of β cell mass. J. Clin. Invest. 112, 527-534 (2003).

Spranger, J., Kroke, A., Möhlig, M., Bergmann, M. M., Ristow, M., Boeing, H., Pfeiffer, A. F. H.: Adiponectin and protection against type 2 diabetes mellitus. Lancet 361, 226-228 (Erratum: Lancet 361, 1060) (2003).

Spranger, J., Kroke, A., Möhlig, M., Hoffmann, K., Bergmann, M. M., Ristow, M., Boeing, H., Pfeiffer, A. F. H.: Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study. Diabetes 52, 812-817 (2003).

Spranger, J., Ristow, M., Otto, B., Heldwein, W., Tschöp, M., Pfeiffer, A. F. H., Möhlig, M.: Post-prandial decrease of human plasma ghrelin in the absence of insulin. J. Endocrinol. Invest. 26, RC19-RC22 (2003).

Assert, R., Kötter, R., Schiemann, U., Goretzki, P., Pfeiffer, A. F.: Effects of the putatively oncogenic protein kinase Cα D294G mutation on enzymatic activity and cell growth and its occurrence in human thyroid neoplasias. Horm. Metab. Res. 34, 311-317 (2002).

Kopp, R., Ruge, M., Rothbauer, E., Cramer, C., Kraemling, H. J., Wiebeck, B., Schildberg, F. W., Pfeiffer, A.: Impact of epidermal growth factor (EGF) radioreceptor analysis on long-term survival of gastric cancer patients. Anticancer Res. 22, 1161-1167 (2002).

Möhlig, M., Spranger, J., Otto, B., Ristow, M., Tschöp, M., Pfeiffer, A. F.: Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans. J. Endocrinol. Invest. 25, RC36-38 (2002).

Möhlig, M., Wegewitz, U., Osterhoff, M., Isken, F., Ristow, M., Pfeiffer, A. F. H., Spranger, J.: Insulin decreases human adiponectin plasma levels. Horm. Metab. Res. 34, 655-658 (2002).

Mühlenhoff, U., Richhardt, N., Ristow, M., Kispal, G., Lill, R.: The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins. Hum. Mol. Genet. 11, 2025-236 (2002).

Schiemann, U., Konturek, J., Assert, R., Rembiasz, K., Domschke, W., Konturek, S., Pfeiffer, A.: mRNA expression of EGF receptor ligands in atrophic gastritis before and after Helicobacter pylori eradication. Med. Sci. Monit. 8, CR53-58 (2002).

Shoichet, S. A., Baumer, A. T., Stamenkovic, D., Sauer, H., Pfeiffer, A. F., Kahn, C. R., Müller-Wieland, D., Richter, C., Ristow, M.: Frataxin promotes antioxidant defense in a thiol-dependent manner resulting in diminished malignant transformation in vitro. Hum. Mol. Genet. 11, 815-821 (2002).

Assert, R., Scherk, G., Bumbure, A., Pirags, V., Schatz, H., Pfeiffer, A. F.: Regulation of protein kinase C by short term hyperglycaemia in human platelets in vivo and in vitro. Diabetologia 44, 188-195 (2001).

Hering, S., Isken, F., Janott, J., Jost, C., Pommer, A., Muhr, G., Schatz, H., Pfeiffer, A. F.: Analysis of TGFbeta3 gene expression and protein levels in human bone and serum. Exp. Clin. Endocrinol. Diabetes 109, 107-115 (2001).

Hering, S., Isken, F., Knabbe, C., Janott, J., Jost, C., Pommer, A., Muhr, G., Schatz, H., Pfeiffer, A. F.: TGFbeta1 and TGFbeta2 mRNA and protein expression in human bone samples. Exp. Clin. Endocrinol. Diabetes 109, 217-226 (2001).

Roudovitch, N., Nauck, M. A., Schatz, H., Pfeiffer, A. F.: Modified hyperinsulinaemic, eu- and hypoglycaemic clamp technique using lispro-insulin for insulinoma diagnostic. Exp. Clin. Endocrinol. Diabetes 109, 397-401 (2001).

Schiemann, U., Konturek, J. W., Osterhoff, M., Assert, R., Rembiasz, K., Pfeiffer, D., Schatz, H., Domschke, W., Pfeiffer, A.: Decreased expression of epidermal growth factor receptor and mRNA of its ligands in Helicobacter pylori-infected gastric mucosa. Scand. J. Gastroenterol. 36, 23-31 (2001).

Spranger, J., Möhlig, M., Osterhoff, M., Buhnen, J., Blum, W. F., Pfeiffer, A. F.: Retinal photocoagulation does not influence intraocular levels of IGF-I, IGF-II and IGF-BP3 in proliferative diabetic retinopathy-evidence for combined treatment of PDR with somatostatin analogues and retinal photocoagulation?. Horm. Metab. Res. 33, 312-316 (2001).

Spranger, J., Osterhoff, M., Reimann, M., Möhlig, M., Ristow, M., Francis, M. K., Cristofalo, V., Hammes, H. P., Smith, G., Boulton, M., Pfeiffer, A. F.: Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease. Diabetes 50, 2641-2645 (2001).

Originalarbeiten (korrespondierender Autor nicht vom DIfE)

Laksir, H., Lansink, M., Regueme, S. C., de Vogel-van den Bosch, J., Pfeiffer, A. F. H., Bourdel-Marchasson, I.: Glycaemic response after intake of a high energy, high protein, diabetes-specific formula in older malnourished or at risk of malnutrition type 2 diabetes patients. Clin. Nutr. in press (E-pub ahead of print) (Open Access) (2018).

Hörbelt, T., Tacke, C., Markova, M., Herzfeld de Wiza, D., Van de Velde, F., Bekaert, M., Van Nieuwenhove, Y., Hornemann, S., Rödiger, M., Seebeck, N., Friedl, E., Jonas, W., Thoresen, G. H., Kuss, O., Rosenthal, A., Lange, V., Pfeiffer, A. F. H., Schürmann, A., Lapauw, B., Rudovich, N., Pivovarova, O., Ouwens, D. M.: The novel adipokine WISP1 associates with insulin resistance and impairs insulin action in human myotubes and mouse hepatocytes. Diabetologia 61, 2054-2065 (2018).

Kühn, C., Kupke, F., Baldermann, S., Klopsch, R., Lamy, E., Hornemann, S., Pfeiffer, A. F. H., Schreiner, M., Hanschen, F. S., Rohn, S.: Diverse excretion pathways of benzyl glucosinolate in humans after consumption of nasturtium (Tropaeolum majus L.)- A pilot study. Mol. Nutr. Food Res. in press (E-pub ahead of print) (2018).

Meyer, S., Markova, M., Pohl, G., Marschall, T. A., Pivovarova, O., Pfeiffer, A. F. H., Schwerdtle, T.: Development, validation and application of an ICP-MS/MS method to quantify minerals and (ultra-)trace elements in human serum. J. Trace Elem. Med. Biol. 49, 157-163 (2018).

Tönjes, A., Scholz, M., Krüger, J., Krause, K., Schleinitz, D., Kirsten, H., Gebhardt, C., Marzi, C., Grallert, H., Ladenvall, C., Heyne, H., Laurila, E., Kriebel, J., Meisinger, C., Rathmann, W., Gieger, C., Groop, L., Prokopenko, I., Isomaa, B., Beutner, F., Kratzsch, J., Fischer-Rosinsky, A., Pfeiffer, A., Krohn, K., Spranger, J., Thiery, J., Blüher, M., Stumvoll, M., Kovacs, P.: Genome wide meta-analysis identifies novel determinants of circulating serum progranulin. Hum. Mol. Genet. 27, 546-558 (2018).

Engstler, A. J., Frahnow, T., Kruse, M., Pfeiffer, A. F. H., Bergheim, I.: Plasminogen activator inhibitor-1 is regulated through dietary fat intake and heritability: studies in twins. Twin Res. Hum. Genet. 20, 338-348 (2017).

Heidenreich, S., Witte, N., Weber, P., Goehring, I., Tolkachov, A., von Loeffelholz, C., Döcke, S., Bauer, M., Stockmann, M., Pfeiffer, A. F. H., Birkenfeld, A. L., Pietzke, M., Kempa, S., Muenzner, M., Schupp, M.: Retinol saturase coordinates liver metabolism by regulating ChREBP activity. Nat. Commun. 8:384 (Open Access) (2017).

Maurer, L., Schwarz, F., Fischer-Rosinsky, A., Schlueter, N., Brachs, S., Möhlig, M., Pfeiffer, A., Mai, K., Spranger, J., Bobbert, T.: Renal function is independently associated with circulating betatrophin. PLoS ONE 12(3):e0173197 (Open Access) (2017).

Merry, T. L., Kuhlow, D., Laube, B., Pöhlmann, D., Pfeiffer, A. F. H., Kahn, C. R., Ristow, M., Zarse, K.: Impairment of insulin signalling in peripheral tissue fails to extend murine lifespan. Aging Cell 16, 761-772 (Open Access) (2017).

van Baak, M. A., Larsen, T. M., Jebb, S. A., Martinez, A., Saris, W. H. M., Handjieva-Darlenska, T., Kafatos, A., Pfeiffer, A. F. H., Kunešová, M., Astrup, A.: Dietary intake of protein from different sources and weight regain, changes in body composition and cardiometabolic risk factors after weight loss: The DIOGenes Study. Nutrients 9(12): 1326 (Open Access) (2017).

Al-Massadi, O., Porteiro, B., Kuhlow, D., Köhler, M., Gonzalez-Rellan, M. J., Garcia-Lavandeira, M., Díaz-Rodríguez, E., Quiñones, M., Senra, A., Alvarez, C. V., López, M., Diéguez, C., Schulz, T., Nogueiras, R.: Pharmacological and genetic manipulation of p53 in brown fat at adult but not embryonic stages regulates thermogenesis and body weight in male mice. Endocrinology 157, 2735-2749 (2016).

Navas-Carretero, S., Holst, C., Saris, W. H., van Baak, M. A., Jebb, S. A., Kafatos, A., Papadaki, A., Pfeiffer, A. F. H., Handjieva-Darlenska, T., Hlavaty, P., Stender, S., Larsen, T. M., Astrup, A., Martinez, J. A.: The impact of gender and protein intake on the success of weight maintenance and associated cardiovascular risk benefits, independent of the mode of food provision: The DiOGenes randomized trial. J. Am. Coll. Nutr. 35, 20-30 (2016).

Platz, S., Kühn, C., Schiess, S., Schreiner, M., Kemper, M., Pivovarova, O., Pfeiffer, A. F. H., Rohn, S.: Bioavailability and metabolism of benzyl glucosinolate in humans consuming Indian cress (Tropaeolum majus L.). Mol. Nutr. Food Res. 60, 652-660 (2016).

Bobbert, T., Schwarz, F., Fischer-Rosinsky, A., Maurer, L., Möhlig, M, Pfeiffer, A. F. H., Mai, K., Spranger, J.: Chemerin and prediction of Diabetes mellitus type 2. Clin. Endocrinol. 82, 838-843 (2015).

Engberink, M. F., Geleijnse, J. M., Bakker, S. J. L., Larsen, T. M., Handjieva-Darlesnka, T., Kafatos, A., Martinez, J. A., Pfeiffer, A. F. H., Kunešová, M., Jebb, S. A., Holst, C., Astrup, A., Saris, W. H. M., Brink, E. J., van Baak, M. A.: Effect of a high-protein diet on maintenance of blood pressure levels achieved after initial weight loss: the DiOGenes randomized study. J. Hum. Hypertens. 29, 58-63 (Open Access) (2015).

Hoppe, S., von Loeffelholz, C., Lock, J. F., Doecke, S., Sinn, B. V., Rieger, A., Malinowski, M., Pfeiffer, A. F. H., Neuhaus, P., Stockmann, M.: Nonalcoholic Steatohepatits and Liver Steatosis Modify Partial Hepatectomy Recovery. J. Invest. Surg. 28, 24-31 (2015).

Mansfeld, J., Urban, N., Priebe, S., Groth, M., Frahm, C., Hartmann, N., Gebauer, J., Ravichandran, M., Dommaschk, A., Schmeisser, S., Kuhlow, D., Monajembashi, S., Bremer-Streck, S., Hemmerich, P., Kiehntopf, M., Zamboni, N., Englert, C., Guthke, R., Kaleta, C., Platzer, M., Sühnel, J., Witte, O. W., Zarse, K., Ristow, M.: Branched-chain amino acid catabolism is a conserved regulator of physiological ageing. Nat. Commun. 6:10043 (Open Access) (2015).

Nowotny, B., Zahiragic, L., Bierwagen, A., Kabisch, S., Groener, J. B., Nowotny, P. J., Fleitmann, A. K., Herder, C., Pacini, G., Erlund, I., Landberg, R., Haering, H.-U., Pfeiffer, A. F. H., Nawroth, P. P., Roden, M.: Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: a randomised feasibility trial. Diabetologia 58, 255-264, [Eratum 59(2016),1329] (2015).

Zhao, C., Du, H., Xu, L., Wang, J., Tang, L., Cao, Y., Li, C., Wang, Q., Liu, Y., Shan, F., Feng, J., Xu, F., Gao, P.: Metabolomic analysis revealed glycylglycine accumulation in astrocytes after methionine enkephalin administration exhibiting neuron protective effects. J. Pharm. Biomed. Anal. 115, 48-54 (2015).

Aller, E. E. J. G., Larsen, T. M., Holst, C., Lindroos, A. K., Kafatos, A., Pfeiffer, A., Martinez, J. A., Handjieva-Darlenska, T., Kunesova, M., Stender, S., Saris, W. H. M., Astrup, A., van Baak, M. A.: Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12 months results. Int. J. Obes. 38, 1511-1517 (2014).

Belavý, D. L., Möhlig, M., Pfeiffer, A. F. H., Felsenberg, D., Armbrecht, G.: Preferential deposition of visceral adipose tissue occurs due to physical inactivity. Int. J. Obes. 38, 1478-1480 (2014).

Bendtsen, L. Q., Lorenzen, J. K., Larsen, T. M., van Baak, M., Papadaki, A., Martinez, J. A., Handjieva-Darlenska, T., Jebb, S. A., Kunešová, M., Pfeiffer, A. F. H., Saris, W. H. M., Astrup, A., Raben, A.: Associations between dairy protein intake and body weight and risk markers of diabetes and CVD during weight maintenance. Br. J. Nutr. 111, 944-953 (2014).

Bidlingmaier, M., Friedrich, N., Emeny, R. T., Spranger, J., Wolthers, O. D., Roswall, J., Koerner, A., Obermayer-Pietsch, B., Hübener, C., Dahlgren, J., Frystyk, J., Pfeiffer, A. F. H., Doering, A., Bielohuby, M., Wallaschofski, H., Arafat, A. M.: Reference intervals for insulin-like growth factor-1 (IGF-1) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-1 immunoassay conforming to recent international recommendations. J. Clin. Endocrinol. Metab. 99, 1712-1721 (2014).

Cuthbertson, D. J., Weickert, M. O., Lythgoe, D., Sprung, V. S., Dobson, R., Shoajee-Moradie, F., Umpleby, M., Pfeiffer, A. F. H., Thomas, E. L., Bell, J. D., Jones, H., Kemp, G. J.: External validation of the fatty liver index and lipid accumulation product indices, using 1H-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals. Eur. J. Endocrinol. 171, 561-569 (2014).

Dimas, A. S., Lagou, V., Barker, A., Knowles, J. W., Mägi, R., Hivert, M.-F., Benazzo, A., Rybin, D., Jackson, A. U., Stringham, H. M., Song, C., Fischer-Rosinsky, A., Boesgaard, T. W., Grarup, N., Abbasi, F. A., Assimes, T. L., Hao, K. , Yang, X., Lecoeur, C., Barroso, I., Bonnycastle, L. L., Böttcher, Y., Bumpstead, S., Chines, P. S., Erdos, M. R., Graessler, J., Kovacs, P., Morken, M. A., Narisu, N., Payne, F., Stancakova, A., Swift, A. J., Tönjes, A., Bornstein, S. R., Cauchi, S., Froguel, P., Meyre, D., Schwarz, P. E. H., Häring, H.-U., Smith, U., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Quertemous, T., Lind, L., Hansen, T., Pedersen, O., Walker, M., Pfeiffer, A. F. H., Spranger, J., Stumvoll, M., Meigs, J. B., Wareham, N. J., Kuusisto, J., Laakso, M., Langenberg, C., Dupuis, J., Watanabe, R. M., Florez, J. C., Ingelsson, E., McCarthy, M. I., Prokopenko, I. on behalf of the MAGIC investigators: Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes 63, 2158-2171 (2014).

Friedrich, N., Wolthers, O. D., Arafat, A. M., Emeny, R. T., Spranger, J., Roswall, J., Kratzsch, J., Grabe, H. J., Hübener, C., Pfeiffer, A. F., Döring, A., Bielohuby, M., Dahlgren, J., Frystyk, J., Wallaschofski, H., Bidlingmaier, M.: Age- and sex-specific reference intervals across life span for insulin-like growth factor binding protein 3 (IGFBP-3) and the IGF-I to IGFBP-3 ratio measured by new automated chemiluminescence assays. J. Clin. Endocrinol. Metab. 99, 1675-1686 (2014).

Neuschäfer-Rube, F., Lieske, S., Kuna, M., Henkel, J., Perry, R. J., Erion, D. M., Pesta, D., Willmes, D. M., Brachs, S., von Loeffelholz, C., Tolkachov, A., Schupp, M., Pathe-Neuschäfer-Rube, A., Pfeiffer, A. F. H., Shulman, G. I., Püschel, G. P., Birkenfeld, A. L.: The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes. Diabetes 63, 1048-1057 (2014).

Papadaki, A., Linardakis, M., Plada, M., Larsen, T. M., Damsgaard, C. T., van Baak, M. A., Jebb, S., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunešová, M., Holst, C., Saris, W. H. M., Astrup, A., Kafatos, A.: Impact of weight loss and maintenance with ad libitum diets varying in protein and glycemic index content on metabolic syndrome. Nutrition 30, 410-417 (2014).

Scheufele, F., Wolf, B., Kruse, M., Hartmann, T., Lempart, J., Muehlich, S., Pfeiffer, A. F. H., Field, L. J., Charron, M. J., Pan, Z.-Q., Engelhardt, S., Sarikas, A.: Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling. Cell. Signal. 26, 233-239 (2014).

Stefan, N., Ramsauer, M., Jordan, P., Nowotny, B., Kantartzis, K., Machann, J., Hwang, J.-H., Nowotny, P., Kahl, S., Harreiter, J., Hornemann, S., Sanyal, A. J., Stewart, P. M., Pfeiffer, A. F., Kautzky-Willer, A., Roden, M., Häring, H.-U., Fürst-Recktenwald, S.: Inhibition of 11β-HSD1 with RO5093151 for non-alcoholic fatty liver disease: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol. 2, 406-416 (2014).

Szabó, T., Scherbakov, N., Sandek, A., Kung, T., von Haehling, S., Lainscak, M., Jankowska, E. A., Rudovich, N., Anker, S. D., Frystyk, J., Flyvbjerg, A., Pfeiffer, A. F. H., Doehner, W.: Plasma adiponectin in heart failure with and without cachexia: Catabolic signal linking catabolism, symptomatic status, and prognosis. Nutr. Metab. Cardiovasc. Dis. 24, 50-56 (2014).

Arafat, A. M., Kaczmarek, P., Skrzypski, M., Pruszyńska-Oszmalek, E., Kołodziejski, P., Szczepankiewicz, D., Sassek, M., Wojciechowicz, T., Wiedenmann, B., Pfeiffer, A. F., Nowak, K. W., Strowski, M. Z.: Glucagon increases circulating fibroblast growth factor 21 independently of endogenous insulin levels: a novel mechanism of glucagon-stimulated lipolysis?. Diabetologia 56, 588-597 (2013).

Bobbert, T., Schwarz, F., Fischer-Rosinsky, A., Pfeiffer, A. F. H., Möhlig, M., Mai, K., Spranger, J.: Fibroblast growth factor 21 predicts the metabolic syndrome and type 2 diabetes in Caucasians. Diabetes Care 36, 145-149 (2013).

Brahe, L. K., Ängquist, L., Larsen, L. H., Vimaleswaran, K. S., Hager, J., Viguerie, N., Loos, R. J. F., Handjieva-Darlenska, T., Jebb, S. A., Hlavaty, P., Larsen, T. M., Martinez, J. A., Papadaki, A., Pfeiffer, A. F. H., van Baak, M. A., Sørensen, T. I. A., Holst, C., Langin, D., Astrup, A., Saris, W. H. M.: Influence of SNPs in nutrient-sensitive candidate genes and gene-diet interactions on blood lipids: the DiOGenes study. Br. J. Nutr. 110, 790-796 (2013).

Keller, M., Schleinitz, D., Förster, J., Tönjes, A., Böttcher, Y., Fischer-Rosinsky, A., Breitfeld, J., Weidle, K., Rayner, N. W., Burkhardt, R., Enigk, B., Müller, I., Halbritter, J., Koriath, M., Pfeiffer, A., Krohn, K., Groop, L., Spranger, J., Stumvoll, M., Kovacs, P. : THOC5: a novel gene involved in HDL-cholesterol metabolism. J.Lipid Res. 54, 3170-3176 (2013).

McConnon, A., Horgan, G. W., Lawton, C., Stubbs, J., Shepherd, R., Astrup, A., Handjieva-Darlenska, T., Kunešová, M., Larsen, T. M., Lindroos, A. K., Martinez, J. A., Papadaki, A., Pfeiffer, A. F. H., van Baak, M. A., Raats, M. M.: Experience and acceptability of diets of varying protein content and glycemic index in an obese cohort: results from the Diogenes trial. Eur. J. Clin. Nutr. 67, 990-995 (2013).

Papadaki, A., Linardakis, M., Plada, M., Larsen, T. M., van Baak, M. A., Lindroos, A. K., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunešová, M., Holst, C., Saris, W. H. M., Astrup, A., Kafatos, A. on behalf of DiOGenes: A multicentre weight loss study using a low-calorie diet over 8 weeks: regional differences in efficacy across eight European cities. Swiss Med. Wkly. 143:w13721 (2013).

Platz, S., Kühn, C., Schiess, S., Schreiner, M., Mewis, I., Kemper, M., Pfeiffer, A., Rohn, S.: Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.). Anal. Bioanal. Chem. 405, 7427-7436 (2013).

Ufer, F., Diederich, S., Pedersen, E. B., Spranger, J., Pfeiffer, A. F., Bähr, V., Mai, K.: Arginine vasopressin-dependent and AVP-independent mechanisms of renal fluid absorption during thirsting despite glucocorticoid-mediated vasopressin suppression. Clin. Endocrinol. 78, 431-437 (2013).

Wagner, R., Thorand, B., Osterhoff, M. A., Müller, G., Böhm, A., Meisinger, C., Kowall, B., Rathmann, W., Kronenberg, F., Staiger, H., Stefan, N., Roden, M., Schwarz, P. E., Pfeiffer, A. F., Häring, H.-U., Fritsche, A.: Family history of diabetes is associated with higher risk for prediabetes: a multicentre analysis from the German Center for Diabetes Research.. Diabetologia 56, 2176-2180 (2013).

Wang, P., Menheere, P. P. C. A., Astrup, A., Andersen, M. R., van Baak, M. A., Larsen, T. M., Jebb, S., Kafatos, A., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Hlavaty, P., Viguerie, N., Langin, D., Saris, W. H. M., Mariman, E. C. M.; Diogenes consortium: Metabolic syndrome, circulating RBP4, testosterone, and SHBG predict weight regain at 6 months after weight loss in men. Obesity 21, 1997-2006 (2013).

Dastani, Z., Hivert, M.-F., Timpson, N., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L.-P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S., Pankow, J. S., Uh, H.-W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M. T., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C.-T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Frants, R., Willems-vanDijk, K., Oostra, B. A., Willems, S. M., Lamina, C., Winkler, T. W., Psaty, B. M., Tracy, R. P., Brody, J., Chen, I., Viikari, J., Kähönen, M., Pramstaller, P. P., Evans, D. M., St. Pourcain, B., Sattar, N., Wood, A. R., Bandinelli, S., Carlson, O. D., Egan, J. M., Böhringer, S., van Heemst, D., Kedenko, L., Kristiansson, K., Nuotio, M.-L., Loo, B.-M., Harris, T., Garcia, M., Kanaya, A., Haun, M., Klopp, N., Wichmann, H.-E., Deloukas, P., Katsareli, E., Couper, D. J., Duncan, B. B., Kloppenburg, M., Adair, L. S., Borja, J. B., DIAGRAM+ Consortium, MAGIC Consortium (Fischer-Rosinsky, A., Pfeiffer, A. F. H., Spranger, J., amongst others), GLGC Investigators, MuTHER Consortium, Wilson, J. G., Musani, S., Guo, X., Johnson, T., Semple, R., Teslovich, T. M., Allison, M. A., Redline, S., Buxbaum, S. G., Mohlke, K. L., Meulenbelt, I., Ballantyne, C. M., Dedoussis, G. V., Hu, F. B., Liu, Y., Paulweber, B., Spector, T. D., Slagboom, P. E., Ferrucci, L., Jula, A., Perola, M., Raitakari, O., Florez, J. C., Salomaa, V., Eriksson, J. G., Frayling, T. M., Hicks, A. A., Lehtimäki, T., Smith, G. D., Siscovick, D. S., Kronenberg, F., van Duijn, C., Loos, R. J. F., Waterworth, D. M., Meigs, J. B., Dupuis, J., Richards, J. B.: Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 8(3):e1002607 Open Access (2012).

Hische, M., Larhlimi, A., Schwarz, F., Fischer-Rosinský, A., Bobbert, T., Assmann, A., Catchpole, G. S., Pfeiffer, A. F. H., Willmitzer, L., Selbig, J., Spranger, J.: A distinct metabolic signature predicts development of fasting plasma glucose. J. Clin. Bioinformatics 2:3 Open Access (2012).

Larsen, L. H., Ängquist, L., Vimaleswaran, K. S., Hager, J., Viguerie, N., Loos, R. J., Handjieva-Darlenska, T., Jebb, S. A., Kunesova, M., Larsen, T. M., Martinez, J. A., Papadaki, A., Pfeiffer, A. F. H., van Baak, M. A., Sørensen, T. I. A., Holst, C., Langin, D., Astrup, A., Saris, W. H. M.: Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: the DIOGENES study. Am. J. Clin. Nutr. 95, 1254-1260 (2012).

Mai, K., Andres, J., Bobbert, T., Assmann, A., Biedasek, K., Diederich, S., Graham, I., Larson, T. R., Pfeiffer, A. F. H., Spranger, J.: Rosiglitazone increases fatty acid δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo. Metabolism 61, 108-116 (2012).

McConnon, A., Raats, M., Astrup, A., Bajzová, M., Handjieva-Darlenska, T., Lindroos, A. K., Martinez, J. A., Larson, T. M., Papadaki, A., Pfeiffer, A., van Baak, M. A., Shepherd, R.: Application of the theory of planned behaviour to weight control in an overweight cohort. Results from a pan-European dietary intervention trial (DiOGenes). Appetite 58, 313-318 (2012).

Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., DIAGRAM Consortium, MAGIC Investigators (Fischer-Rosinsky, A., Pfeiffer, A. F. H., Spranger, J. amongst others), Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N., Ng, M. C. Y., Langefeld, C. D., Freedman, B. I., Bowden, D. W.: A genome-wide association search for type 2 diabetes genes in African Americans. PLoS ONE 7(1):e29202 Open Access (2012).

Stocks, T., Ängquist, L., Banasik, K., Harder, M. N., Taylor, M. A., Hager, J., Arner, P., Oppert, J.-M., Martinez, J. A., Polak, J., Rousseau, F., Langin, D., Rössner, S., Holst, C., MacDonald, I. A., Kamatani, Y., Pfeiffer, A. F. H., Kunesova, M., Saris, W. H. M., Hansen, T., Pedersen, O., Astrup, A., Sørensen, T. I. A.: TFAP2B influences the effect of dietary fat on weight loss under energy restriction. PLoS ONE 7(8): e43212 (2012).

Wang, P., Holst, C., Astrup, A., Bouwman, F. G., van Otterdijk, S., Wodzig,W. K. W. H., Andersen, M. R., van Baak, M. A., Rasmussen, L. G., Martinez, J. A., Jebb, S. A., Pfeiffer, A. F. H., Kafatos, A., Handjieva-Darlenksa, T., Hlavaty, P., Saris and W. H. M., Mariman, E. C. M. on behalf of DIOGENES Consortium: Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index. Br. J. Nutr. 107, 106-119 (2012).

Wang, P., Holst, C., Wodzig, W. K. W. H., Andersen, M. R., Astrup, A., van Baak, M. A., Larsen, T. M., Jebb, S. A., Kafatos, A., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunesova, M., Viguerie, N., Langin, D., Saris, W. H. M. and Mariman, E. C. M. on behalf of Diogenes consortium: Circulating ACE is a predictor of weight loss maintenance not only in overweight and obese women, but also in men. Int. J. Obes. 36, 1545-1551 (2012).

Weidner, C., de Groot, J. C., Prasad, A., Freiwald, A., Quedenau, C., Kliem, M., Witzke, A., Kodelja, V., Han, C.-T., Giegold, S., Baumann, M., Klebl, B., Siems, K., Müller-Kuhrt, L., Schürmann, A., Schüler, R., Pfeiffer, A. F. H., Schroeder, F. C., Büssow, K., Sauer, S.: Amorfrutins are potent antidiabetic dietary natural products. Proc. Natl. Acad. Sci. 109, 7257-7262 (2012).

Kulozik, P. Jones, A., Mattijssen, F., Rose, A. J., Reimann, A., Strzoda, D., Kleinsorg, S., Raupp, C., Kleinschmidt, J., Müller-Decker, K., Wahli, W., Sticht, C., Gretz, N., von Loeffelholz, C., Stockmann, M., Pfeiffer, A., Stöhr, S., Dallinga-Thie, G. M., Nawroth, P. P., Diaz, M. B., Herzig, S.: Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia. Cell Metab. 13, 389-400 (2011).

Mai, K., Schwarz, F., Bobbert, T., Andres, J., Assmann, A., Pfeiffer, A. F. H., Spranger, J.: Relation between fibroblast growth factor-21, adiposity, metabolism, and weight reduction. Metabolism 60, 306-311 (2011).

Wang, P., Holst, C., Andersen, M. R., Astrup, A., Bouwman, F. G., van Otterdijk, S., Wodzig, W. K. W. H., van Baak, M. A., Larsen, T. M., Jebb, S. A., Kafatos, A., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunesova, M., Saris, W. H. M., Mariman, E. C. M.: Blood profile of proteins and steroid hormones predicts weight change after weight loss with interactions of dietary protein level and glycemic index. PLoS ONE 6(2): e16773 (Open Access) (2011).

Dupuis, J., ..., Fischer-Rosinsky, A., Pfeifer, A. F., Spranger, J. amongst others, ..., Barroso, I.: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat. Genet. 42, 105-116, Erratum 464 (2010).

Handjieva-Darlenska, T., Handjiev, S., Larsen, T. M., van Baak, M. A., Jebb, S., Papadaki, A., Pfeiffer, A. F. H., Martinez, J. A., Kunesova, M., Holst, C., Saris, W. H. M., Astrup, A.: Initial weight loss on an 800-kcal diet as a predictor of weight loss success after 8 weeks: the Diogenes study. Eur. J. Clin. Nutr. 64, 994-999 (2010).

Henze, A., Frey, S. K., Raila, J., Scholze, A., Spranger, J., Weickert, M. O., Tepel, M., Zidek, W., Schweigert, F. J.: Alterations of retinol-binding protein 4 species in patients with different stages of chronic kidney disease and their relation to lipid parameters. Biochem. Biophys. Res. Commun. 393, 79-83 (2010).

Hische, M., Luis-Dominguez, O., Pfeiffer, A. F. H., Schwarz, P. E., Selbig, J., Spranger, J.: Decision trees as a simple-to-use and reliable tool to identify individuals with impaired glucose metabolism or type 2 diabetes mellitus. Eur. J. Endocrinol. 163, 565-571 (2010).

James, W. P. T., Caterson, I. D., Coutinho, W., Finer, N., Van Gaal, L. F., Maggioni, A. P., Torp-Pedersen, C., Sharma, A. M., Shepherd, G. M., Rode, R. A., Remz, C. L., for the Scout Investigators (amongst others Pfeiffer, A. F. H.): Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N. Engl. J. Med. 363, 905-917 (2010).

Larsen, T. M., Dalskov, S.-M., van Baak, M., Jebb, S. A., Papadaki, A., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunešová, M., Pihlsgård, M., Stender, S., Holst, C., Saris, W. H. M. and Astrup, A. for the Diet, Obesity, and Genes (Diogenes) Project: Diets with high or low protein content and glycemic index for weight-loss maintenance. N. Engl. J. Med. 363, 2102-2113 (2010).

Lindström, J., Neumann, A., Sheppard, K. E., Gilis-Januszewska, A., Greaves, C. J., Handke, U., Pajunen, P., Puhl, S., Pölönen, A., Rissanen, A., Roden, M., Stemper, T., Telle-Hjellset, V., Tuomilehto, J., Velickiene, D., Schwarz, P. E. on behalf of the IMAGE Study Group on behalf of the IMAGE Study Group (Pfeiffer, A. amongst others): Take action to prevent diabetes – The IMAGE toolkit for the prevention of type 2 diabetes in Europe. Horm. Metab. Res. 42 (Suppl. 1), S37-S55 (2010).

Mai, K., Bobbert, T., Groth, C., Assmann, A., Meinus, S., Kraatz, J., Andres, J., Arafat, A. M., Pfeiffer, A. F. H., Möhlig, M., Spranger, J.: Physiological modulation of circulating FGF21: relevance of free fatty acids and insulin. Am. J. Physiol./Endocrinol. Metab. 299, E126-E130 (2010).

Márquez-Quiñones, A., Mutch, D. M., Debard, C., Wang, P., Combes, M., Roussel, B., Holst, C., Martinez, J. A., Handjieva-Darlenska, T., Kalouska, P., Jebb, S., Babalis, D., Pfeiffer, A. F. H., Larsen, T. M., Astrup, A., Saris, W. H. M., Mariman, E., Clément, K., Vidal, H., Langin, D. and Viguerie, N. on behalf of the DiOGenes Project: Adipose tissue transcriptome reflects variations between subjects with continued weight loss and subjects regaining weight 6 mo after caloric restriction independent of energy intake. Am. J. Clin. Nutr. 92, 975-984 (2010).

Pajunen, P., Landgraf, R., Muylle, F., Neumann, A., Lindström, J., Schwarz, P. E., Peltonen, M. for the IMAGE Study Group (Pfeiffer, A. amongst others): Quality indicators for the prevention of type 2 diabetes in Europe – IMAGE. Horm. Metab. Res. 42 (Suppl. 1), S56-S63 (2010).

Papadaki, A., Linardakis, M., Larsen, T. M., van Baak, M. A., Lindroos, A. K., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunesová, M., Holst, C., Astrup, A., Saris, W. H. M., Kafatos, A. on behalf of the DiOGenes Study Group : The effect of protein and glycemic index on children's body composition: The DiOGenes randomized study. Pediatrics 126, e1143-e1152 (2010).

Paulweber, B., Valensi, P., Lindström, J., Lalic, N. M., Greaves, C. J., McKee, M., Kissimova-Skarbek, K., Liatis, S., Cosson, E., Szendroedi, J., Sheppard, K. E., Charlesworth, K., Felton, A.-M., Hall, M., Rissanen, A., Tuomilehto, J., Schwarz, P. E., Roden, M. for the Writing Group, on behalf of the IMAGE Study Group (Pfeiffer, A. amongst others): A European evidence-based guideline for the prevention of type 2 diabetes. Horm. Metab. Res. 42 (Suppl. 1), S3-S36 (2010).

Swinnen, S. G., Dain, M.-P., Aronson, R., Davies, M., Gerstein, H. C., Pfeiffer, A. F. H., Snoek, F. J., DeVries, J. H., Hoekstra, J. B., Holleman, F.: A 24-week, randomized, treat-to-target trial comparing initiation of insulin glargine once-daily with insulin detemir twice-daily in patients with type 2 diabetes inadequately controlled on oral glucose-lowering drugs. Diabetes Care 33, 1176-1178 (2010).

Frey, S. K., Spranger, J., Henze, A., Pfeiffer, A. F. H., Schweigert, F. J., Raila, J.: Factors that influence retinol-binding protein 4-transthyretin interaction are not altered in overweight subjects and overweight subjects with type 2 diabetes mellitus. Metabolism 58, 1386-1392 (2009).

Huth, C., Illig, T., Herder, C., Gieger, C., Grallert, H., Vollmert, C., Rathmann, W., Hamid, Y. H., Pedersen, O., Hansen, T., Thorand, B., Meisinger, C., Döring, A., Klopp, N., Gohlke, H., Lieb, W., Hengstenberg, C., Lyssenko, V., Groop, L., Ireland, H., Stephens, J. W., Wernstedt Asterholm, I., Jansson, J.-O., Boeing, H., Möhlig, M., Stringham, H. M., Boehnke, M., Tuomilehto, J., Fernandez-Real, J.-M., Lopez-Bermejo, A., Gallart, L., Vendrell, J., Humphries, S. E., Kronenberg, F., Wichmann, H.-E., Heid, I. M.: Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index. Ann. Med. 41, 128-138 (2009).

Kopp, R., Fichter, M., Assert, R., Pfeiffer, A. F., Classen, S.: Butyrate-induced alterations of phosphoinositide metabolism, protein kinase C activity and reduced CD44 variant expression in HT-29 colon cancer cells. Int. J. Mol. Med. 23, 639-649 (2009).

Tönjes, A., Koriath, M., Schleinitz, D., Dietrich, K., Böttcher, Y., Rayner, N. W., Almgren, P., Enigk, B., Richter, O., Rohm, S., Fischer-Rosinsky, A., Pfeiffer, A., Hoffmann, K., Krohn, K., Aust, G., Spranger, J., Groop, L., Blüher, M., Kovacs, P., Stumvoll, M. : Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs. Hum. Mol. Genet. 18, 4662-4668 (2009).

Frey, S. K., Nagl, B., Henze, A., Raila, J., Schlosser, B., Berg, T., Tepel, M., Zidek, W., Weickert, M. O., Pfeiffer, A. F. H., Schweigert, F. J.: Isoforms of retinol binding protein 4 (RBP4) are increased in chronic disease of the kidney but not of the liver. Lipids Health Dis. 7:29 (Open Access) (2008).

Henze, A., Frey, S. K., Raila, J., Tepel, M., Scholze, A., Pfeiffer, A. F. H., Weickert, M. O. , Spranger, J., Schweigert, F. J.: Evidence that kidney function but not type 2 diabetes determines retinol-binding protein 4 serum levels. Diabetes 57, 3323-3326 (2008).

Wolever, T. M. S., Brand-Miller, J. C., Abernethy, J., Astrup, A., Atkinson, F., Axelsen, M., Björck, I., Brighenti, F., Brown, R., Brynes, A., Casiraghi, M. C., Cazaubiel, M., Dahlqvist, L., Delport, E., Denyer, G. S., Erba, D., Frost, G., Granfeldt, Y., Hampton, S., Hart, V. A., Hätönen, K. A., Henry, C. J., Hertzler, S., Hull, S., Jerling, J., Johnston, K. L., Lightowler, H., Mann, N., Morgan, L., Panlasigui, L. N., Pelkman, C., Perry, T., Pfeiffer, A. F. H., Pieters, M., Dan Ramdath, D., Ramsingh, R. T., Robert, S. D., Robinson, C., Sarkkinen, E., Scazzina, F., Sison, D. C. D., Sloth, B., Staniforth, J., Tapola, N., Valsta, L. M., Verkooijen, I., Weickert, M. O., Weseler, A. R., Wilkie, P., Zhang, J.: Measuring the glycemic index of foods: interlaboratory study. Am. J. Clin. Nutr. 87(Suppl), 247S-257S (2008).

Beulens, J. W. J., van Loon, L. J. C., Kok, F. J., Pelsers, M., Bobbert, T., Spranger, J., Helander, A., Hendriks, H. F. J.: The effects of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: a human intervention study. Diabetologia 50, 1388-1392 (2007).

Birringer, M., Kuhlow, D., Pfluger, P. T., Landes, N., Schulz, T. J., Glaubitz, M., Florian, S., Pfeiffer, A., Schuelke, M., Brigelius-Flohé, R., Ristow, M.: Improved glucose metabolism in mice lacking α-tocopherol transfer protein. Eur. J. Nutr. 46, 397-405 (2007).

Engl, J., Bobbert, T., Ciardi, C., Laimer, M., Tatarczyk, T., Kaser, S., Weiss, H., Molnar, C., Tilg, H., Patsch, J. R., Spranger, J., Ebenbichler, C. F.: Effects of pronounced weight loss on adiponectin oligomer composition and metabolic parameters. Obesity 15, 1172-1178 (2007).

Mai, K., Andres, J., Bobbert, T., Maser-Gluth, C., Möhlig, M., Bähr, V., Pfeiffer, A. F. H., Spranger, J., Diederich, S.: Rosiglitazone decreases 11β-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue. Clin. Endocrinol. 67, 419-425 (2007).

Nitz, I., Fisher, E., Grallert, H., Li. Y., Gieger, C., Rubin, D., Boeing, H., Spranger, J., Lindner, I., Schreiber, S., Rathmann, W., Gohlke, H., Döring, A., Wichmann, H.-E., Schrezenmeir, J., Döring, F., Illig, T.: Association of prostaglandin E Synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations. J. Clin. Endocrinol. Metab. 92, 3183-3188 (2007).

Nitz, I., Fisher, E., Weikert, C., Burwinkel, B., Li, Y., Möhlig, M., Boeing, H., Schreiber, S., Schrezenmeir, J., Döring, F.: Association analyses of GIP and GIPR polymorphisms with traits of the metabolic syndrome. Mol. Nutr. Food Res. 51, 1046-1052 (2007).

Otto, C., Otto, B., Frost, R. J. A., Vogeser, M., Pfeiffer, A. F. H., Spranger, J., Parhofer, K. G.: Short-term therapy with atorvastatin or fenofibrate does not affect plasma ghrelin, resistin or adiponectin levels in type 2 diabetic patients with mixed hyperlipoproteinaemia. Acta Diabetol. 44, 65-68 (2007).

Pfluger, P. T., Kampe, J., Castaneda, T. R., Vahl, T., D'Alessio, D. A., Kruthaupt, T., Benoit, S. C., Cuntz, U., Rochlitz, H. J., Moehlig, M., Pfeiffer, A. F. H., Koebnick, C., Weickert, M. O., Spranger, J., Tschöp, M. H.: Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36. J. Clin. Endocrinol. Metab. 92, 583-588 (2007).

Raila, J., Henze, A., Spranger, J., Möhlig, M., Pfeiffer, A. F. H., Schweigert, F. J.: Microalbuminuria is a major determinant of elevated plasma retinol-binding protein 4 in type 2 diabetes patients. Kidney Int. 72, 505-511 (2007).

Zarse, K., Schulz, T. J., Birringer, M., Ristow, M.: Impaired respiration is positively correlatde with decreased life span in Caenorhabditis elegans models of Friedreich ataxia. FASEB J. 21, 1271-1275 (2007).

Huth, C., Heid, I. M., Vollmert, C., Gieger, C., Grallert, H., Wolford, J. K., Langer, B., Thorand, B., Klopp, N., Hamid, Y. H., Pedersen, O., Hansen, T., Lyssenko, V., Groop, L., Meisinger, C., Döring, A., Löwel, H., Lieb, W., Hengstenberg, C., Rathmann, W., Martin, S., Stephens, J. W., Ireland, H., Mather, H., Miller, G. J., Stringham, H. M., Boehnke, M., Tuomilehto, J., Boeing, H., Möhlig, M., Spranger, J., Pfeiffer, A., Wernstedt, I., Niklason, A., López-Bermejo, A., Fernández-Real, J.-M., Hanson, R. L., Gallart, L., Vendrell, J., Tsiavou, A., Hatziagelaki, E., Humphries, S. E., Wichmann, H.-E., Herder, C., Illig, T. : IL6 Gene promoter polymorphisms and type 2 diabetes: Joint analysis of individual participants’ data from 21 studies. Diabetes 55, 2915-2921 (2006).

Li, Y., Fisher, E., Klapper, M., Boeing, H., Pfeiffer, A., Hampe, J., Schreiber, S., Burwinkel, B., Schrezenmeir, J., Döring, F.: Association between functional FABP2 promoter haplotype and type 2 Diabetes. Horm. Metab. Res. 38, 300-307 (2006).

Otto, C., Otto, B., Göke, B., Pfeiffer, A. F. H. , Lehrke, M., Vogeser, M., Spranger, J., Parhofer, K. G.: Increase in adiponectin levels during pioglitazone therapy in relation to glucose control, insulin resistance as well as ghrelin and resistin levles. J. Endocrinol. Invest. 29, 231-236 (2006).

Rubin, D., Helwig, U., Pfeuffer, M., Schreiber, S., Boeing, H., Fisher, E., Pfeiffer, A., Freitag-Wolf, S., Foelsch, U. R., Doering, F., Schrezenmeir, J.: A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels. J. Hum. Genet. 51, 567-574 (2006).

Kopp, H.-P., Krzyzanowska, K., Möhlig, M., Spranger, J., Pfeiffer, A. F. H., Schernthaner, G.: Effects of marked weight loss on plasma levels of adiponectin, markers of chronic subclinical inflammation and insulin resistance in morbidly obese women. Int. J. Obes. 29, 766-771 (2005).

Lindner, I., Helwig, U., Rubin, D., Li, Y., Fisher, E., Boeing, H., Möhlig, M., Spranger, J., Pfeiffer, A., Hampe, J., Schreiber, S., Döring, F., Schrezenmeir, J.: Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations. Mol. Nutr. Food Res. 49, 972-976 (2005).

Mai, K., Kullmann, V., Bobbert, T., Maser-Gluth, C., Möhlig, M., Bähr, V., Pfeiffer, A. F. H., Spranger, J., Diederich, S.: In vivo activity of 11β-hydroxysteroid dehydrogenase type 1 and free fatty acid-induced insulin resistance. Clin. Endocrinol. 63, 442-449 (2005).

Übersichtsarbeiten

Klaus, S., Pfeiffer, A. F. H., Boeing, H., Laeger, T., Grune, T.: Das Proteinparadox: Viel oder wenig Nahrungsprotein - was ist besser für die Gesundheit? [The protein paradox: how much dietary protein is good for health?]. Ernaehr.-Umsch. 65, 42-47 (2018).

Pfeiffer, A. F. H., Keyhani-Nejad, F.: High glycemic index metabolic damage - a pivotal role of GIP and GLP-1. Trends. Endocrinol. Metab. 29, 289-299 (2018).

Weickert, M. O., Pfeiffer, A. F. H.: Impact of dietary fiber consumption on insulin resistance and the prevention of type 2 diabetes. J. Nutr. 148, 7-12 (Open Access) (2018).

Peters, H. P. F., Schrauwen, P., Verhoef, P., Byrne, C. D., Mela, D. J., Pfeiffer, A. F. H., Risérus, U., Rosendaal, F. R., Schrauwen-Hinderling, V.: Liver fat: a relevant target for dietary intervention? Summary of a Unilever workshop. J. Nutr. 6:e15 (Open Access) (2017).

Pfeiffer, A. F. H.: Hepatogenous diabetes. Diabetologe 12, 468-472 (2016).

Pfeiffer, A. F. H.: Microbiome. Diabetologe 12, 384-385 (Editorial) (2016).

Pfeiffer, A. F. H., Gebauer, S., Rubin, D., Schulze, M., Buchholz, G., Klein, H., von Lilienfeld-Toal, H., Reinert, G., Simon, M. C., Mussig, K., Skurk, T., Hauner, H., Tombek, A., Mueller, M. J., Fischer, S., Weickert, M. O., Hoffmann, D.: Ernährungsempfehlungen zur Behandlung des Diabetes mellitus – Empfehlungen zur Proteinzufuhr [Nutritional recommendations for the treatment of diabetes mellitus - recommendations for protein intake]. Diabetol. Stoffw. 11, 272-282 (2016).

Pivovarova, O., Höhn, A., Grune, T., Pfeiffer, A. F. H., Rudovich, N.: Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer’s disease?. Ann. Med. 48, 614-624 (2016).

Gebauer, S., Pfeiffer, A. F. H.: Diabetes und Ernährung. Diabetologe 10, 390-395 (2014).

Pfeiffer, A. F. H., Klein, H. H.: The treatment of type 2 diabetes. Dtsch. Arztebl. Int. 111, 69-82 (2014).

Birringer, M., Ristow, M.: Effektivität und Risiken der Supplementierung mit Antioxidanzien, Teil 1. Ernaehr. Umsch. 59, 10-14 (2012).

Birringer, M., Ristow, M.: Effektivität und Risiken der Supplementierung mit Antioxidanzien, Teil 2. Ernaehr. Umsch. 59, 142-146 (2012).

Thomas, T., Pfeiffer, A. F. H.: Foods for the prevention of diabetes: How do they work?. Diabetes Metab. Res. Rev. 28, 25-49 (2012).

Pfeiffer, A. F. H., Rudovich, N., Weickert, M. O., Isken, F.: Role of the gut peptide glucose-induced insulinomimetric peptide in energy balance. In: Meyerhof, W., Beisiegel, U., Joost, H.-G. (eds.) Sensory and Metabolic Control of Energy Balance (Results and Problems in Cell Differentiation; 52), Springer, pp 183-188 (2010).

Weickert, M. O., Pfeiffer, A. F.: Metabolic effects of dietary fiber consumption and prevention of diabetes. J. Nutr. 138, 439-442 (2008).

Pfeiffer, A. F. H.: Adipose tissue and diabetes therapy: Do we hit the target?. Horm. Metab. Res. 39, 734-738 (2007).

Pfeiffer, A. F. H., Bramlage, P.: Rimonabant zur Behandlung des diabetes mellitus Typ 2 - Serenade-Studie. Diabetologe 3, 270-277 (2007).

Pfeiffer, A. F. H., Kohl, A.: Komplexe diätetische und Pharmakotherapie beim metabolischen Syndrom. Internist 48, 164-172 (2007).

Weickert, M. O., Pfeiffer, A. F. H.: Ballaststoffe, glykämischer Index und Diabetesprävention. Aktuel. Ernaehr. Med. 32, 175-180 (2007).

Regitz-Zagrosek, V., Lehmkuhl, E., Weickert, M. O.: Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clin. Res. Cardiol. 95, 136-147 (2006).

Weickert, M. O., Pfeiffer, A. F.,: Signalling mechanisms linking hepatic glucose and lipid metabolism. Diabetologia 49, 1732-1741 (2006).

Weickert, M. O., Pfeiffer, A. F. H.: Ballaststoffe und Prävention des Typ-2-Diabetes. Ernährung & Medizin 20, 185-189 (2005).

Weickert, M. O., Pfeiffer, A. F.: Unlösliche Ballaststoffe schützen vor Typ-2-Diabetes. MMW Fortschr. Med. 147, 28-30 (2005).

Ristow, M.: Neurodegenerative disorders associated with diabetes mellitus. J. Mol. Med. 82, 510-529 (2004).

Schumm-Draeger, P.-M., Diederich, S., Dören, M., Faßbender, W. J., Mann, B., Raue, F., Schilling, T., Weber, M. M., Pfeiffer, A. F. H.: Endokrinologie - Teil I. Med. Klin. 99, 293-308 (2004).

Schumm-Draeger, P.-M., Diederich, S., Dören, M., Faßbender, W. J., Mann, B., Raue, F., Schilling, T., Weber, M. M., Pfeiffer, A. F. H.: Endokrinologie - Teil II. Med. Klin. 99, 372-382 (2004).

Spranger, J., Möhlig, M., Pfeiffer, A. F. H.: Das metabolische Syndrom: Bedeutung von Zytokinen als endokrine und metabolische Signalmoleküle. Aktuel. Ernaehr. Med. 28, 143-150 (2003).

Bähr, V., Diederich, S., Pfeiffer, A. F.: The metabolic syndrome X and peripheral cortisol synthesis. Exp. Clin. Endocrinol. Diabetes 110, 313-318 (2002).

Fiehn, O., Spranger, J.: Can metabolomics be used for assessing nutritive-dependent human diseases?. Phytochem. Rev. 1, 223-230 (2002).

Pfeiffer, A. F., Einig, C.: Prävention mit Vitaminen und Spurenelementen. Dtsch. Med. Wochenschr. 127, 2251-2252 (German) (2002).

Müller-Wieland, D., Knebel, B., Avci, H., Lehr, S., Laudes, M., Ristow, M., Krone, W., Kotzka, J.: Insulin-regulated transcription factors: molecular link between insulin resistance and cardiovascular risk factors. Int. J. Obes. Relat. Metab. Disord. 25, Suppl 1, S35-S37 (2001).

Spranger, J., Pfeiffer, A. F. H.: New concepts in pathogenesis and treatment of diabetic retinopathy. Exp. Clin. Endocrinol. Diabetes 109, Suppl. 2, S438-S450 (2001).

Buchbeiträge

Pfeiffer, A. F. H.: Kohlenhydrate und Zuckerstoffwechsel des Menschen. In: Koesling, V., Spierling, R. (Hrsg.) Alles Zucker! Nahrung - Werkstoff - Energie. be.bra Verlag, Berlin, S. 131-140 (2017).

Hillmann, H., Meyer, S., Dunkel, A., Behrens, M., Kemper, M., Ley, J., Reichelt, K., Pfeiffer, A. F. H., Meyerhof, W., Hofmann, T.: Influence of taste stimuli on peptide hormones and metabolites of the carbohydrate metabolism. In: Hofmann, T., Krautwurst, D., Schieberle, P. (eds.) Current Topics in Flavor Chemistry and Biology (Proceedings of the 10th Wartburg Symposium on Flavor Chemistry & Biology) Deutsche Forschungsanstalt für Lebensmittelchemie, Freising, pp. 270-273 (2014).

Kabisch, S., Pfeiffer, A. F. H.: Genetik des Diabetes mellitus. In: Schatz, H., Pfeiffer, A. F. H. (Hrsg.) Diabetologie kompakt. Grundlagen und Praxis. 5. Aufl., Springer, Berlin Heidelberg, S. 4-8 (2014).

Pfeiffer, A. F. H.: Ernährung, Stoffwechsel und Gesundheit. In: Schärer-Züblin, E. V. (Hrsg.) Forschung und Ernährung - ein Dialog. Alimentarium, Wiley-Blackwell, Weinheim, 2009, S. 161-164 (2009).

Pfeiffer, A. F. H.: Regulation des Essverhaltens. In: Schauder, P., Ollenschläger, G. (Hrsg.) Ernährungsmedizin - Prävention und Therapie. 3. Aufl., Urban & Fischer, München, S. 45-50 (2006).

Pfeiffer, A. F. H.: Die verschiendenen Formen der Zuckerkrankheit und deren Genetik. In: Schauder, P., Ollenschläger, G. (Hrsg.) Ernährungsmedizin - Prävention und Therapie. 3. Aufl., Urban & Fischer, München, S. 829-834 (2006).

Fiehn, O., Spranger, J.: Use of metabolomics to discover metabolic patterns associated with human diseases. In: Harrigan, G. G., Godacre, R. (eds.) Metabolic profiling. Its role in biomarker discovery and gene function analysis. Kluwer Academic Publishers, Boston/Dordrecht/London Chapter 11, pp 199-215 (2003).

Pfeiffer, A. F. H.: Regulation des Eßverhaltens. In: Schauder, P., Ollenschläger, G. (Hrsg.) Ernährungsmedizin - Prävention und Therapie. 2. Aufl., Urban & Fischer, München, S. 35-39 (2003).

Spranger, J., Pfeiffer, A.: Diabetische Retinopathie. In: Hasslacher, S. (Hrsg.) Diabetische Nephropathie - Prävention und Therapie. Vol. 1. Uni-Med, Bremen, S. 56-60 (2003).

Pfeiffer, A. F. H.: Die verschiedenen Formen der Zuckerkrankheit und deren Genetik. In: Schatz, H. (Hrsg.) Diabetologie kompakt. Berlin, Wien 2001, S. 5-13 (2002).

Pfeiffer, A. F. H.: Künstliches Pankreas. In: Schatz, H. (Hrsg.) Diabetologie kompakt. Berlin, Wien 2001, S. 91-92 (2002).

Pfeiffer, A. F. H.: Perspektiven des biotechnologischen Ersatzes insulinsezernierender Zellen. In: Schatz, H. (Hrsg.) Diabetologie kompakt. Berlin, Wien 2001, S. 100-103 (2002).

Spranger, J., Pfeiffer, A.: Diabetic microvascular complications. In: Mogensen, C. (ed.) Hypertension & Diabetes. Volume 1. London, Lippincott Williams & Wilkins,, pp 57-68 (2002).

Herausgeber

Schatz, H., Pfeiffer, A. F. H.: Diabetologie kompakt. Grundlagen und Praxis. 5. Aufl., Springer, Berlin Heidelberg (2014).

sonstige Arbeiten

Keyhani-Nejad, F., Kemper, M., Schueler, R., Pivovarova, O., Rudovich, N., Pfeiffer, A. F. H.: Effects of palatinose and sucrose intake on glucose metabolism and incretin secretion in subjects with type 2 diabetes. Diabetes Care 39:e38-39 (e-Letter) (2016).

Rudovich, N. N., Weickert, M. O., Machann, J., Pfeiffer, A. F. H.: Combination of acarbose and ezetimibe prevents non-alcoholic fatty liver disease: A break of intestinal insulin resistance? . J. Hepatol. 52, 952-952 (Letter to the Editor) (2010).

Pfeiffer, A. F. H., Nitschmann, S.: Längerfristige Effektivität unterschiedlicher Diätstragetien: Vergleich unterschiedlich hoher Fett-, Protein- bzw. Kohlenhydratanteile [Long-term effectiveness of different dietary strategies: comparision of different compositions of fat, protein and carbohydrates]. Internist 50, 1290-1292 (2009).

Weickert, M. O., Pfeiffer, A. F. H.: Low-glycemic index vs high-cereal fiber diet in type 2 diabetes. JAMA 301, 1538 (Letter to the editor) (2009).

Bähr, V., Pfeiffer, A. F. H.: Is there a need for vitamin C supplementation of the normal diet? Effects of in vivo ascorbate depletion on adrenal function. Am. J. Clin. Nutr. 87, 191 (Letter) (2008).

Pfeiffer, A. F. H., Gerbracht, C.: Gleichzeitige Einnahme von Magnesium- und Eisenpräparaten bei Schwangeren. Gynäkol. Prax. 32, 733-734 (2008).

Bähr, V., Oelkers, W., Pfeiffer, A. F. H., Diederich, S.: Metabolism of synthetic steroids by the human placenta. Placenta 28, 588-589 (Letter) (2007).

Schulze, M. B., Hoffmann, K., Boeing, H., Linseisen, J., Pfeiffer, A. F. H., Fritsche, A., Häring, H.-U., Joost, H.-G.: Eine einfache, präzise und validierte Bestimmung des Typ-2-Diabetes-Risikos. Der Deutsche Diabetes-Risiko-Score (DRS). Diabetologie Stoffwechsel 2, 86-89 (2007).

Weickert, M. O., Pfeiffer, A. F. H. : Reply to comment on: Weickert, M. O., Pfeiffer, A. F. H. (2006) Signalling mechanisms linking hepatic glucose and lipid metabolism. Diabetologia 49:1732-1741. Diabetologia 50, 495-496 (Letter) (2007).

Hauner, H., Landgraf, R., Schulze, J., Spranger, J., Standl, E.: Prävention des Typ-2-Diabetes mellitus. Dtsch. Med. Wochenschr. 130, 1053-1054 (2005).

Jacobs, B., Muller, M. K., Pfeiffer, A. F. : Diabetes mellitus und massive Unterschenkelödeme ohne Herzinsuffizienz. Dtsch. Med. Wochenschr. 130, 1074-1077 (2005).

Pfeiffer, A. F.: Präventionsstrategien für Prädiabetes(Editorial). Dtsch. Med. Wochenschr. 130, 1059-1060 (2005).

Bahr, V., Bumke-Vogt, C., Götze, J., Pfeiffer, A. F., Diederich, S.: Function of human mineralocorticoid receptor splice variant. Eur. J. Endocrinol. 151, 295 (2004).

Reschke, K., Pfeiffer, A. F., Lehnert, H.: Substitutionstherapie mit Hormonen: Was ist gesichert?. Internist 44, 98-109 (2003).

Ristow, M., Mulder, H., Pomplun, D., Krause, A., Schulz, T. J., Fex, M., Puccio, H., Stamenkovic, D., Spranger, J., Müller-Wieland, D., Magnuson, M. A., Möhlig, M., Koenig, M., Pfeiffer, A. F. H.: β-cell specific disruption of the frataxin gene in mice leads to impaired insulin secretion and diabetes mellitus caused by reactive oxygen species. Diabetes 51, Suppl. 2, A372, 1523-P (2002).

Ziemssen, F., Bellanne-Chantelot, C., Osterhoff, M., Schatz, H., Pfeiffer, A. F.: To: Lindner, T., Cockburn, B. N., Bell, G. I. (1999) Molecular genetics of MODY in Germany. Diabetologia 45, 286-287 (2002).

Behre, A., Janott, J., Pfohl, M., Schatz, H., Pfeiffer, A. F.: [Clinical value of urinary pyridinium crosslinks as osteoporosis markers: evaluation of a population survey of vertebral osteoporosis]. Med. Klin. 96, 378-382 (German) (2001).

Ziemssen, F., Schnepf, R., Pfeiffer, A. F.: [SSCP (single strand conformation polymorphism) analysis for detection of point mutations. A technique and its limits exemplified by dominantly inherited forms of diabetes (MODY)]. Med. Klin. 96, 515-520 (German) (2001).

Abstracts

Möhlig, M., Kopp, H. P., Spranger, J., Krzyzanowska, K., Kriwanek, S., Osterhoff, M., Ristow, M., Schernthaner, G., Pfeiffer, A. F. H.: Who profits most from weight reduction? Weight reduction decreases IL-6 levels dependent on the C-174G polymorphism within the IL-6 promotor. Diabetologia 46, Suppl. 2, 759 (2003).

Rudovich, N. N., Rochlitz, H., Dieken, M. G. L., Pfeiffer, A. F. H.: Comparison of effects of repaglinide and nateglinide on insulin secretion and postloading glucose excursions in patients with Type 2 diabetes. Diabetologia 48, Suppl. 2, 816 (2003).

Ortmann, S., Ristow, M., Klaus, S.: Selektive Leptin-Resistenz bei transgenen UCP-DTA Mäusen mit zerstörtem braunen Fettgewebe. Aktuel. Ernaehr. Med. 27, 347 (2002).

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