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Status: 24.01.2018 02:43:08
Carbohydrates, proteins and fats are the three macronutrients in our diets. They provide our bodies with energy and with building blocks, and thus play an important role in the development of obesity and its associated health problems (such as insulin insensitivity). However, not only nutrient amount and composition are decisive but also their interactions with genetic factors play an integral role. These interactions are the basis for our studies in which we focus on the metabolic regulation of the interplay of important organs such as the intestinal tract, liver, skeletal muscle, and adipose tissue. Using mainly animal models, we examine how macronutrients interact with energy and substrate metabolism in order to identify and characterize in detail the physiological and molecular mechanisms leading to obesity development. The ultimate aim is to find new and efficient approaches to obesity prevention and therapy.
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