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Status: 31.05.2016 09:39:02
Investigation of the role of nutrient-dependent factors in the pathogenesis of major diseases of industrialized countries (e.g.: obesity, fatty liver disease, diabetes mellitus, atherosclerosis and metabolic syndrome).
Obesity appears to be a central constellation inducing the components of the metabolic syndrome, which includes important genetic effects. The metabolic syndrome describes the frequent clustering of the risk components which provide the common soil for atherosclerosis, type 2 diabetes, and at least several types of cancer. The metabolic syndrome includes the following components: disturbed glucose metabolism, central obesity, dyslipidemia with low HDL-cholesterol and raised triglycerides, hypertension, microalbuminuria, and disturbed fibrinolysis.
The department (together with the departments DIAB and MEP) is a member of the German Center for Diabetes Research (DZD). The DZD was founded in 2009 as one of six national health centers by the Federal Ministry of Education and Research. The DZD is a national research consortium in which basic researchers, clinicians and epidemiologists closely collaborate in order to clarify the causes and pathophysiology of diabetes and to develop individualized approaches to prevention and treatments.
The main focus of our studies is the prevention of metabolic syndrome through personalized nutrition based on an understanding of the molecular mechanisms governing metabolism.
In addition, Prof. Pfeiffer treats patients at the Medical Department of Endocrinology, Diabetes and Nutritional Medicine of the Charité Berlin (Campus Benjamin Franklin).