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Status: 12.08.2020 16:58:50
As an internationally renowned research institute for nutrition-associated diseases, the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) is one of the five founding partners of the DZD. In cooperation with other DZD partners, DIfE scientists elucidate the pathogenesis of type 2 diabetes in order to develop new strategies for the prevention and therapy of this disease.
Together with Helmholtz Zentrum München, DIfE pursues a particularly innovative research approach in collaboration with the German Mouse Clinic. Here scientists use mouse models to identify genes associated with diabetes and to characterize these as to their function. In this way they obtain profound insight into the molecular mechanisms involved in the development of diabetes. Through a better understanding of these mechanisms the researchers seek to develop new approaches for drug therapies.
Based on the data of the Potsdam EPIC (European Prospective Investigation into Cancer and Nutrition) Study, epidemiologists at DIfE have developed the German Diabetes Risk Score (DIfE – DEUTSCHER DIABETES-RISIKO-TEST®) to investigate the links between lifestyle, biomarkers and diabetes risk. The cooperation between the partners in the DZD enables the joint evaluation of the data of the Potsdam EPIC Study and KORA (Cooperative Health Research in the Augsburg Region) Study. Findings from these studies are promptly incorporated into the German Diabetes Risk Score.
Furthermore, the DIfE contributes its expertise to multicenter DZD studies for primary and secondary prevention of diabetes.
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