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Status: 12.12.2018 08:00:34

Laboratory, Department of Experimental Diabetology (© Till Budde/Zukunftsagentur Brandenburg; This picture was financed by the European Regional Development Fund.)

New Marker Provides Insights into the Development of Type 2 Diabetes

Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes increase the risk of type 2 diabetes. Moreover, people with high blood levels of the binding protein IGFBP2 are less likely to develop this metabolic disorder. The changes in the blood are already detectable a few years prior to the onset of the disease.

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German Institute of Human Nutrition

The mission of the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) is to conduct experimental and clinical research in the field of nutrition and health. Scientists at the DIfE pursue these scientific goals by interdisciplinary cooperation comprising a broad spectrum of experimental, medical and epidemiological methods.

Therefore the researchers focus on three areas:

The aim is to understand the molecular basis of nutrition-dependent diseases, and to develop new strategies for prevention, treatment, and nutritional recommendations.

DIfE is an independent foundation and member of the Leibniz Association, an alliance of scientific institutions.

© 2018 DIfE - German Institute of Human Nutrition. All rights reserved. // as of 09.11.2018

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